Transplanted hypothalamic neurons restore leptin signaling and ameliorate obesity in db/db mice. (Q42601745)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116886%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Transplanted hypothalamic neurons restore leptin signaling and ameliorate obesity in db/db mice (English)

1 reference

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17 January 2020

0 references

2

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17 January 2020

6

Jeffrey S Flier

1 reference

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17 January 2020

author name string

Artur Czupryn

1

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17 January 2020

Xi Chen

3

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17 January 2020

David McNay

4

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17 January 2020

Matthew P Anderson

5

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17 January 2020

Jeffrey D Macklis

7

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17 January 2020

language of work or name

English

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publication date

1 November 2011

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17 January 2020

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17 January 2020

volume

334

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17 January 2020

page(s)

1133-1137

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17 January 2020

issue

6059

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Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility

17 January 2020

cites work

1 reference

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Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits

28 May 2018

1 reference

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Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy.

28 May 2018

1 reference

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Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion

28 May 2018

1 reference

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AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons

28 May 2018

1 reference

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Adult neurogenesis and cellular brain repair with neural progenitors, precursors and stem cells

28 May 2018

1 reference

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Mash1 is required for generic and subtype differentiation of hypothalamic neuroendocrine cells

28 May 2018

1 reference

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Cholinergic modulation of appetite-related synapses in mouse lateral hypothalamic slice

28 May 2018

1 reference

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Neurogenesis in the hypothalamus of adult mice: potential role in energy balance

28 May 2018

1 reference

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Obesity wars: molecular progress confronts an expanding epidemic

28 May 2018

1 reference

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STAT3 signalling is required for leptin regulation of energy balance but not reproduction

28 May 2018

1 reference

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Late-stage immature neocortical neurons reconstruct interhemispheric connections and form synaptic contacts with increased efficiency in adult mouse cortex undergoing targeted neurodegeneration.

28 May 2018

1 reference

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Functional neurogenesis in the adult hippocampus

28 May 2018

1 reference

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Selective deletion of leptin receptor in neurons leads to obesity

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770458

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770458

Transplanted neuroblasts differentiate appropriately into projection neurons with correct neurotransmitter and receptor phenotype in neocortex undergoing targeted projection neuron degeneration.

28 May 2018

1 reference

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Targeted neuronal death affects neuronal replacement and vocal behavior in adult songbirds.

28 May 2018

1 reference

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Leptin receptor activation of SH2 domain containing protein tyrosine phosphatase 2 modulates Ob receptor signal transduction

28 May 2018

1 reference

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Leptin and the regulation of body weight in mammals

28 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770458

Embryonic neurons transplanted to regions of targeted photolytic cell death in adult mouse somatosensory cortex re-form specific callosal projections

28 May 2018

1 reference

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Time of neuron origin in mouse hypothalamic nuclei.

28 May 2018

1 reference

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Electrophysiological properties and glucose responsiveness of guinea-pig ventromedial hypothalamic neurones in vitro.

28 May 2018

1 reference

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Evidence for constitutive neural cell proliferation in the adult murine hypothalamus.

28 May 2018

1 reference

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Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity.

16 August 2018

1 reference

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Characterization of glucosensing neuron subpopulations in the arcuate nucleus: integration in neuropeptide Y and pro-opio melanocortin networks?

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770458

IGF-I specifically enhances axon outgrowth of corticospinal motor neurons.

16 August 2018

1 reference

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Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis.

16 August 2018

1 reference

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Orexigen-sensitive NPY/AgRP pacemaker neurons in the hypothalamic arcuate nucleus

16 August 2018

1 reference

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Role of Signal Transducer and Activator of Transcription 3 in Regulation of Hypothalamic Proopiomelanocortin Gene Expression by Leptin

16 August 2018

1 reference

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Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels

16 August 2018

1 reference

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Cholecystokinin tunes firing of an electrically distinct subset of arcuate nucleus neurons by activating A-Type potassium channels.

16 August 2018

1 reference

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ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3770458

Transgenic complementation of leptin-receptor deficiency. I. Rescue of the obesity/diabetes phenotype of LEPR-null mice expressing a LEPR-B transgene

16 August 2018

1 reference

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16 August 2018

Identifiers

DOI

10.1126/SCIENCE.1209870

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116886%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22116886%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference