Influence of inoculum size and marbofloxacin plasma exposure on the amplification of resistant subpopulations of Klebsiella pneumoniae in a rat lung infection model. (Q42612081)

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scientific article published on 8 September 2009

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English	Influence of inoculum size and marbofloxacin plasma exposure on the amplification of resistant subpopulations of Klebsiella pneumoniae in a rat lung infection model.	scientific article published on 8 September 2009

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7 February 2020

Influence of inoculum size and marbofloxacin plasma exposure on the amplification of resistant subpopulations of Klebsiella pneumoniae in a rat lung infection model (English)

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7 February 2020

Klebsiella pneumoniae

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2

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7 February 2020

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7 February 2020

Alain Bousquet-Mélou

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7 February 2020

Pierre-Louis Toutain

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Pierre-Louis Toutain

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7 February 2020

Anne-Sylvie Kesteman

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Anne-Sylvie Kesteman

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7 February 2020

Michel Laurentie

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Michel Laurentie

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7 February 2020

Agnès Perrin-Guyomard

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Agnès Perrin-Guyomard

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7 February 2020

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8 September 2009

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7 February 2020

Antimicrobial Agents and Chemotherapy

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7 February 2020

53

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7 February 2020

11

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7 February 2020

4740-4748

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7 February 2020

Pharmacokinetic/pharmacodynamic analysis of the influence of inoculum size on the selection of resistance in Escherichia coli by a quinolone in a mouse thigh bacterial infection model

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Enrichment of fluoroquinolone-resistant Staphylococcus aureus: oscillating ciprofloxacin concentrations simulated at the upper and lower portions of the mutant selection window

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In vitro infection model characterizing the effect of efflux pump inhibition on prevention of resistance to levofloxacin and ciprofloxacin in Streptococcus pneumoniae

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Mutant selection window hypothesis updated.

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Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs: an update

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Mutant selection window in levofloxacin and moxifloxacin treatments of experimental pneumococcal pneumonia in a rabbit model of human therapy.

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In vitro pharmacodynamic evaluation of the mutant selection window hypothesis using four fluoroquinolones against Staphylococcus aureus.

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Pharmacodynamics of the new fluoroquinolone gatifloxacin in murine thigh and lung infection models

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Selection of Streptococcus pneumoniae mutants having reduced susceptibility to moxifloxacin and levofloxacin.

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Restricting the selection of antibiotic-resistant mutants: a general strategy derived from fluoroquinolone studies

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Mutant prevention concentrations of fluoroquinolones for clinical isolates of Streptococcus pneumoniae.

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Effects of bacterial endotoxin on drug pharmacokinetics.

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Topoisomerase IV is a target of quinolones in Escherichia coli

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Pharmacodynamics of a fluoroquinolone antimicrobial agent in a neutropenic rat model of Pseudomonas sepsis

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Correlation of antimicrobial pharmacokinetic parameters with therapeutic efficacy in an animal model

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Standardization of pharmacokinetic/pharmacodynamic (PK/PD) terminology for anti-infective drugs

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clarification of MPC and the mutant selection window concept

1 reference

https://pubmed.ncbi.nlm.nih.gov/19738020

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.00608-09

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19738020%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PMC publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19738020%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19738020%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

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