The 8ab protein of SARS-CoV is a luminal ER membrane-associated protein and induces the activation of ATF6. (Q42615665)

3 November 2017

The 8ab protein of SARS-CoV is a luminal ER membrane-associated protein and induces the activation of ATF6. (English)

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protein non-structural 8a [SARS-Cov]

3 November 2017

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protein non-structural 8b [SARS-Cov]

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5

Michael M C Lai

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3 November 2017

3

King-Song Jeng

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3 November 2017

Shu-Chiun Sung

1

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3 November 2017

Che-Yi Chao

series ordinal

2

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3 November 2017

Jyh-Yuan Yang

series ordinal

4

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3 November 2017

language of work or name

English

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publication date

21 March 2009

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3 November 2017

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3 November 2017

387

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3 November 2017

2

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3 November 2017

402-413

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Modulation of the unfolded protein response by the severe acute respiratory syndrome coronavirus spike protein

3 November 2017

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the Golgi

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Molecular evolution of the SARS coronavirus during the course of the SARS epidemic in China

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Perk is essential for translational regulation and cell survival during the unfolded protein response

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Viruses, endoplasmic reticulum stress, and interferon responses

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

The hepatitis C virus RNA-dependent RNA polymerase membrane insertion sequence is a transmembrane segment

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

The human severe acute respiratory syndrome coronavirus (SARS-CoV) 8b protein is distinct from its counterpart in animal SARS-CoV and down-regulates the expression of the envelope protein in infected cells

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Activation of the grp78 and grp94 promoters by hepatitis C virus E2 envelope protein

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Topology of the Membrane-Associated Hepatitis C Virus Protein NS4B

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

The Genome sequence of the SARS-associated coronavirus

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

The 29-nucleotide deletion present in human but not in animal severe acute respiratory syndrome coronaviruses disrupts the functional expression of open reading frame 8.

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Roles of CHOP/GADD153 in endoplasmic reticulum stress

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2alpha kinase PERK

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Coronavirus as a possible cause of severe acute respiratory syndrome

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Characterization of a novel coronavirus associated with severe acute respiratory syndrome

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

A trip to the ER: coping with stress

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Enhanced green fluorescent protein expression may be used to monitor murine coronavirus spread in vitro and in the mouse central nervous system

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

The mammalian unfolded protein response

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

ER stress signaling by regulated proteolysis of ATF6

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Stable binding of ATF6 to BiP in the endoplasmic reticulum stress response

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

ERdj3, a stress-inducible endoplasmic reticulum DnaJ homologue, serves as a cofactor for BiP's interactions with unfolded substrates

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Engineering the transmissible gastroenteritis virus genome as an expression vector inducing lactogenic immunity

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

SARS--beginning to understand a new virus

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Understanding the accessory viral proteins unique to the severe acute respiratory syndrome (SARS) coronavirus.

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Hepatitis C virus suppresses the IRE1-XBP1 pathway of the unfolded protein response

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Hepatitis C virus subgenomic replicons induce endoplasmic reticulum stress activating an intracellular signaling pathway

12 September 2020

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Hepatitis C virus, ER stress, and oxidative stress

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Cloning of mammalian Ire1 reveals diversity in the ER stress responses

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response.

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

A time-dependent phase shift in the mammalian unfolded protein response

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

ATF6 activated by proteolysis binds in the presence of NF-Y (CBF) directly to the cis-acting element responsible for the mammalian unfolded protein response

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

Severe acute respiratory syndrome coronavirus group-specific open reading frames encode nonessential functions for replication in cell cultures and mice

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

12 September 2020

1 reference

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103415

10.1016/J.VIROL.2009.02.021

12 September 2020

Identifiers

DOI

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3 November 2017

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