Molecular dynamics simulations of human cystatin C and its L68Q varient to investigate the domain swapping mechanism (Q42629832)

4 November 2017

title

Molecular dynamics simulations of human cystatin C and its L68Q varient to investigate the domain swapping mechanism (English)

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4 November 2017

Hsuan-Liang Liu

1

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4 November 2017

Yuan-Min Lin

2

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4 November 2017

Jian-Hua Zhao

3

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4 November 2017

Man-Ching Hsieh

4

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4 November 2017

Hsin-Yi Lin

5

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4 November 2017

Chih-Hung Huang

6

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4 November 2017

Hsu-Wei Fang

7

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4 November 2017

Yih Ho

8

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4 November 2017

Wen-Yih Chen

9

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4 November 2017

publication date

1 October 2007

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Journal of Biomolecular Structure and Dynamics

4 November 2017

published in

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4 November 2017

volume

25

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4 November 2017

issue

2

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4 November 2017

page(s)

135-144

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Cystatin-C and mortality in elderly persons with heart failure.

4 November 2017

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Increased body temperature accelerates aggregation of the Leu-68-->Gln mutant cystatin C, the amyloid-forming protein in hereditary cystatin C amyloid angiopathy.

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A proposed structural model for amyloid fibril elongation: domain swapping forms an interdigitating beta-structure polymer

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Prevention of domain swapping inhibits dimerization and amyloid fibril formation of cystatin C: use of engineered disulfide bridges, antibodies, and carboxymethylpapain to stabilize the monomeric form of cystatin C.

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Cystatin C. Icelandic-like mutation in an animal model of cerebrovascular beta-amyloidosis

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Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping

21 January 2018

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Domain swapping: entangling alliances between proteins

21 January 2018

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Two stable unfolding intermediates of the disease-causing L68Q variant of human cystatin C.

21 January 2018

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Insight into ribonuclease A domain swapping by molecular dynamics unfolding simulations

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Increasing temperature accelerates protein unfolding without changing the pathway of unfolding

21 January 2018

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The molecular basis of the temperature- and pH-induced conformational transitions in elastin-based peptides

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Derivation of class II force fields. VI. Carbohydrate compounds and anomeric effects

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Thermal and guanidine hydrochloride-induced denaturation of human cystatin C.

21 January 2018

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Protein under pressure: molecular dynamics simulation of the arc repressor.

21 January 2018

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Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

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Distinct properties of wild-type and the amyloidogenic human cystatin C variant of hereditary cerebral hemorrhage with amyloidosis, Icelandic type

21 January 2018

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Hydrophobicity of amino acid residues in globular proteins.

21 January 2018

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Recent atomic models of amyloid fibril structure

21 January 2018

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NMR structural studies of human cystatin C dimers and monomers

21 January 2018

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Expression of a selenomethionyl derivative and preliminary crystallographic studies of human cystatin C

21 January 2018

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Conformational Variability of Chicken Cystatin

21 January 2018

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Checking the conformational stability of cystatin C and its L68Q variant by molecular dynamics studies: Why is the L68Q variant amyloidogenic?

21 January 2018

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3D domain-swapped human cystatin C with amyloidlike intermolecular β-sheets

21 January 2018

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10.1080/07391102.2007.10507162

21 January 2018

Identifiers

DOI

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4 November 2017

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