The effect of simvastatin treatment on the amyloid precursor protein and brain cholesterol metabolism in patients with Alzheimer's disease (Q42651492)

4 November 2017

The effect of simvastatin treatment on the amyloid precursor protein and brain cholesterol metabolism in patients with Alzheimer's disease (English)

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4 November 2017

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Blennow K

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4 November 2017

7

Vanmechelen E

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4 November 2017

1

Hoglund K

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4 November 2017

4

Sjogren M

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4 November 2017

Thelen KM

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4 November 2017

Syversen S

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4 November 2017

von Bergmann K

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4 November 2017

Wallin A

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4 November 2017

Vanderstichele H

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4 November 2017

Lutjohann D

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4 November 2017

21 March 2005

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Dementia and Geriatric Cognitive Disorders

4 November 2017

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4 November 2017

19

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4 November 2017

256-265

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4 November 2017

5-6

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APOE genotype: no influence on galantamine treatment efficacy nor on rate of decline in Alzheimer's disease

4 November 2017

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Removal of cholesterol from extrahepatic sources by oxidative mechanisms

21 January 2018

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Cholesterol metabolism in the brain

21 January 2018

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Diet and risk of dementia: Does fat matter?: The Rotterdam Study

21 January 2018

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Cholesterol-dependent modulation of tau phosphorylation in cultured neurons

21 January 2018

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Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

21 January 2018

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Effects of statins on human cerebral cholesterol metabolism and secretion of Alzheimer amyloid peptide

21 January 2018

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21 January 2018

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Treatment with controlled-release lovastatin decreases serum concentrations of human beta-amyloid (A beta) peptide

21 January 2018

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MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial

21 January 2018

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Plasma levels of beta-amyloid(1-40), beta-amyloid(1-42), and total beta-amyloid remain unaffected in adult patients with hypercholesterolemia after treatment with statins

21 January 2018

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Pravastatin at 10 mg/day does not decrease plasma levels of either amyloid-β (Aβ) 40 or Aβ 42 in humans

21 January 2018

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Statins and the risk of dementia

21 January 2018

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Effect of atorvastatin treatment on lipoprotein lipase mass in the pre-heparin plasma in Japanese hyperlipidemic subjects

21 January 2018

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Reduction of plasma 24S-hydroxycholesterol (cerebrosterol) levels using high-dosage simvastatin in patients with hypercholesterolemia: evidence that simvastatin affects cholesterol metabolism in the human brain

21 January 2018

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Caloric intake and the risk of Alzheimer disease.

21 January 2018

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Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

21 January 2018

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Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

21 January 2018

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Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease.

21 January 2018

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Amyloid beta protein 1-40 and 1-42 levels in matched cerebrospinal fluid and plasma from patients with Alzheimer disease.

21 January 2018

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Blockade of HMG-CoA reductase activity causes changes in microtubule-stabilizing protein tau via suppression of geranylgeranylpyrophosphate formation: implications for Alzheimer's disease

21 January 2018

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Regulation of amyloid precursor protein cleavage.

21 January 2018

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Dietary fats and the risk of incident Alzheimer disease

21 January 2018

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Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease

21 January 2018

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Measurement of alpha- and beta-secretase cleaved amyloid precursor protein in cerebrospinal fluid from Alzheimer patients

21 January 2018

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24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia

21 January 2018

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Mild hypercholesterolemia is an early risk factor for the development of Alzheimer amyloid pathology

21 January 2018

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Lovastatin enhances Abeta production and senile plaque deposition in female Tg2576 mice

21 January 2018

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Changes in Apolipoprotein E Expression in Response to Dietary and Pharmacological Modulation of Cholesterol

21 January 2018

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Apolipoprotein E and cholesterol metabolism in the pathogenesis and treatment of Alzheimer's disease

21 January 2018

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Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

21 January 2018

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Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls

21 January 2018

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Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial

21 January 2018

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Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

21 January 2018

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Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial

21 January 2018

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Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol.

21 January 2018

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A longitudinal study of Alzheimer's disease: measurement, rate, and predictors of cognitive deterioration.

21 January 2018

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Amyloid beta protein in plasma from patients with sporadic Alzheimer's disease.

21 January 2018

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Plasma total cholesterol level as a risk factor for Alzheimer disease: the Framingham Study

21 January 2018

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Cognitive deterioration in Alzheimer's disease: behavioral and health factors.

21 January 2018

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Dose-response effects of atorvastatin and simvastatin on high-density lipoprotein cholesterol in hypercholesterolaemic patients: a review of five comparative studies

21 January 2018

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Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

21 January 2018

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No association between the α2-macroglobulin (A2M) deletion and Alzheimer's disease, and no change in A2M mRNA, protein, or protein expression

21 January 2018

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21 January 2018

Identifiers

DOI

10.1159/000084550

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4 November 2017

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