Anoxia-induced NMDA receptor activation opens pannexin channels via Src family kinases (Q42666777)

22956847

4 November 2017

title

Anoxia-induced NMDA receptor activation opens pannexin channels via Src family kinases (English)

1 reference

4 November 2017

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621249&resulttype=core&format=json

15 May 2020

author name string

Nicholas L Weilinger

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621249&resulttype=core&format=json

15 May 2020

Peter L Tang

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621249&resulttype=core&format=json

15 May 2020

language of work or name

English

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publication date

1 September 2012

1 reference

22956847

4 November 2017

published in

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621249&resulttype=core&format=json

15 May 2020

volume

32

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621249&resulttype=core&format=json

15 May 2020

issue

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621249&resulttype=core&format=json

15 May 2020

page(s)

12579-12588

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The changing landscape of ischaemic brain injury mechanisms.

15 May 2020

cites work

1 reference

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Pathobiology of ischaemic stroke: an integrated view

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The effect of transient global ischemia on the interaction of Src and Fyn with the N-methyl-D-aspartate receptor and postsynaptic densities: possible involvement of Src homology 2 domains

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Ischemic cell death in brain neurons

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Glutamate release in severe brain ischaemia is mainly by reversed uptake.

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Calcium ion transients in peri-infarct depolarizations may deteriorate ion homeostasis and expand infarction in focal cerebral ischemia in cats

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Enhanced spontaneous transmitter release is the earliest consequence of neocortical hypoxia that can explain the disruption of normal circuit function.

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A key role for TRPM7 channels in anoxic neuronal death

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12 December 2020

Activation of voltage-sensitive sodium channels during oxygen deprivation leads to apoptotic neuronal death

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12 December 2020

Pharmacological properties of homomeric and heteromeric pannexin hemichannels expressed in Xenopus oocytes.

1 reference

12 December 2020

Involvement of TRP-like channels in the acute ischemic response of hippocampal CA1 neurons in brain slices.

1 reference

12 December 2020

Ischemia opens neuronal gap junction hemichannels

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12 December 2020

Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor

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12 December 2020

Astrocyte metabolism and signaling during brain ischemia

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12 December 2020

Two-photon imaging of stroke onset in vivo reveals that NMDA-receptor independent ischemic depolarization is the major cause of rapid reversible damage to dendrites and spines

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Role for nitric oxide in permeability of hippocampal neuronal hemichannels during oxygen glucose deprivation

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Distribution of Wfs1 protein in the central nervous system of the mouse and its relation to clinical symptoms of the Wolfram syndrome

1 reference

12 December 2020

P2X7 receptor-Pannexin1 complex: pharmacology and signaling

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12 December 2020

Probenecid, a gout remedy, inhibits pannexin 1 channels

1 reference

12 December 2020

Connexin and pannexin hemichannels of neurons and astrocytes.

1 reference

12 December 2020

Activation of pannexin-1 hemichannels augments aberrant bursting in the hippocampus.

1 reference

12 December 2020

Ca2+-dependent induction of TRPM2 currents in hippocampal neurons

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12 December 2020

Pannexin 1 contributes to ATP release in airway epithelia.

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12 December 2020

The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death

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Non-junction functions of pannexin-1 channels

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12 December 2020

Metabolic autocrine regulation of neurons involves cooperation among pannexin hemichannels, adenosine receptors, and KATP channels

1 reference

12 December 2020

The role of pannexin hemichannels in the anoxic depolarization of hippocampal pyramidal cells

1 reference

12 December 2020

Pannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosis

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12 December 2020

Targeting pannexin1 improves seizure outcome

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12 December 2020

Dysregulated Src upregulation of NMDA receptor activity: a common link in chronic pain and schizophrenia

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12 December 2020

Pannexins in ischemia-induced neurodegeneration

1 reference

12 December 2020

Examining protection from anoxic depolarization by the drugs dibucaine and carbetapentane using whole cell recording from CA1 neurons

1 reference

12 December 2020

Pannexin 1, an ATP release channel, is activated by caspase cleavage of its pore-associated C-terminal autoinhibitory region

1 reference

12 December 2020

Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis

1 reference

12 December 2020

Sustained dendritic gradients of Ca2+ induced by excitatory amino acids in CA1 hippocampal neurons

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12 December 2020

Differential expression of three gap junction proteins in developing and mature brain tissues

1 reference

12 December 2020

Direct evidence that excitotoxicity in cultured neurons is mediated via N-methyl-D-aspartate (NMDA) as well as non-NMDA receptors

1 reference

12 December 2020

Selective neuronal vulnerability: morphological and molecular characteristics

1 reference

12 December 2020

Effect of anoxia on ion distribution in the brain

1 reference

12 December 2020

Characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus (pp60v-src) and its normal cellular homologue (pp60c-src)

1 reference

12 December 2020

Analysis of the sequence of amino acids surrounding sites of tyrosine phosphorylation

1 reference

12 December 2020

Regional cerebral blood flow and glucose metabolism following transient forebrain ischemia

1 reference

12 December 2020

Binding of the Src SH2 domain to phosphopeptides is determined by residues in both the SH2 domain and the phosphopeptides

1 reference

12 December 2020

The early events of oxygen and glucose deprivation: setting the scene for neuronal death?

1 reference

12 December 2020

SH2 domains recognize specific phosphopeptide sequences

1 reference

12 December 2020

Correlation between peri-infarct DC shifts and ischaemic neuronal damage in rat.

1 reference

12 December 2020

Cerebral energy metabolism during severe ischemia of varying duration and following reperfusion

1 reference

12 December 2020

NMDA channel regulation by channel-associated protein tyrosine kinase Src.

1 reference

12 December 2020

Anoxia-induced neuronal injury: role of Na+ entry and Na+-dependent transport

1 reference

12 December 2020

Transient ischemia differentially increases tyrosine phosphorylation of NMDA receptor subunits 2A and 2B.

1 reference

12 December 2020

Factors that reverse the persistent depolarization produced by deprivation of oxygen and glucose in rat hippocampal CA1 neurons in vitro

1 reference

12 December 2020

Early sodium elevations induced by combined oxygen and glucose deprivation in pyramidal cortical neurons

1 reference

12 December 2020

10.1523/JNEUROSCI.1267-12.2012

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621249&resulttype=core&format=json

15 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621249&resulttype=core&format=json

15 May 2020

22956847

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6621249&resulttype=core&format=json