Effects of ATP depletion and phosphate analogues on P-glycoprotein conformation in live cells (Q42677720)

4 November 2017

title

Effects of ATP depletion and phosphate analogues on P-glycoprotein conformation in live cells (English)

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4 November 2017

Katalin Goda

1

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4 November 2017

Henrietta Nagy

2

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4 November 2017

Eugene Mechetner

3

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4 November 2017

Maurizio Cianfriglia

4

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4 November 2017

Gábor Szabó

5

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4 November 2017

language of work or name

English

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publication date

1 June 2002

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4 November 2017

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4 November 2017

volume

269

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4 November 2017

issue

11

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4 November 2017

page(s)

2672-2677

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Biochemistry of multidrug resistance mediated by the multidrug transporter

4 November 2017

cites work

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https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Clinical relevance of P-glycoprotein expression in haematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Genetic analysis of the multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Characterization of phosphorylation-defective mutants of human P-glycoprotein expressed in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

A general pattern for substrate recognition by P-glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Transition-state formation in ATPase-negative mutants of human MDR1 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

P-glycoprotein Is Stably Inhibited by Vanadate-induced Trapping of Nucleotide at a Single Catalytic Site

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Mechanism of action of human P-glycoprotein ATPase activity. Photochemical cleavage during a catalytic transition state using orthovanadate reveals cross-talk between the two ATP sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Human P-glycoprotein exhibits reduced affinity for substrates during a catalytic transition state

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

P-glycoprotein function involves conformational transitions detectable by differential immunoreactivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Nucleotide-induced conformational changes in P-glycoprotein and in nucleotide binding site mutants monitored by trypsin sensitivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

P-Glycoprotein conformational changes detected by antibody competition

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Use of vanadate as protein-phosphotyrosine phosphatase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Flow cytometric resonance energy transfer measurements support the association of a 95-kDa peptide termed T27 with the 55-kDa Tac peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Calcein accumulation as a fluorometric functional assay of the multidrug transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Analysis of MDR1 P-glycoprotein conformational changes in permeabilized cells using differential immunoreactivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Cysteine-scanning mutagenesis provides no evidence for the extracellular accessibility of the nucleotide-binding domains of the multidrug resistance transporter P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

GTP-stimulated phosphorylation of P-glycoprotein in transporting vesicles from KB-V1 multidrug resistant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Both ATP sites of human P-glycoprotein are essential but not symmetric

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Structural flexibility of the linker region of human P-glycoprotein permits ATP hydrolysis and drug transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Competition of hydrophobic peptides, cytotoxic drugs, and chemosensitizers on a common P-glycoprotein pharmacophore as revealed by its ATPase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Membrane fluidization by ether, other anesthetics, and certain agents abolishes P-glycoprotein ATPase activity and modulates efflux from multidrug-resistant cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Effects of cardiovascular drugs on ATPase activity of P-glycoprotein in plasma membranes and in purified reconstituted form

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Inhibition of P-glycoprotein ATPase activity by procedures involving trapping of nucleotide in catalytic sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Inhibition of P-glycoprotein ATPase activity by beryllium fluoride

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Modulation of human P-glycoprotein epitope expression by temperature and/or resistance-modulating agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Hydrophobic adsorption chromatography to reduce nonspecific staining by rhodamine-labeled antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

Intracellular pH does not affect drug extrusion by P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

P-glycoprotein-independent decrease in drug accumulation by phorbol ester treatment of tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1432-1033.2002.02929.X

10.1046/J.1432-1033.2002.02929.X

21 January 2018

Identifiers

DOI

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4 November 2017

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