A conserved aspartate determines pore properties of anion channels associated with excitatory amino acid transporter 4 (EAAT4). (Q42680906)

4 November 2017

A conserved aspartate determines pore properties of anion channels associated with excitatory amino acid transporter 4 (EAAT4). (English)

1 reference

4 November 2017

4

1 reference

4 November 2017

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Peter Kovermann

1

1 reference

4 November 2017

Jan-Philipp Machtens

series ordinal

2

1 reference

4 November 2017

David Ewers

series ordinal

3

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4 November 2017

language of work or name

English

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publication date

2 June 2010

1 reference

Journal of Biological Chemistry

4 November 2017

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4 November 2017

285

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4 November 2017

31

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4 November 2017

23676-23686

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Transport mechanism of a bacterial homologue of glutamate transporters.

4 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Gating of human ClC-2 chloride channels and regulation by carboxy-terminal domains

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Slips, leaks and channels in glutamate transporters

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Glutamate forward and reverse transport: from molecular mechanism to transporter-mediated release after ischemia

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Neuronal glutamate transporters vary in substrate transport rate but not in unitary anion channel conductance

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Cooperation of the conserved aspartate 439 and bound amino acid substrate is important for high-affinity Na+ binding to the glutamate transporter EAAC1

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Intersubunit interactions in EAAT4 glutamate transporters.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Neutralization of the aspartic acid residue Asp-367, but not Asp-454, inhibits binding of Na+ to the glutamate-free form and cycling of the glutamate transporter EAAC1.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

A dynamic switch between inhibitory and excitatory currents in a neuronal glutamate transporter

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Principles of selective ion transport in channels and pumps

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

The glutamate transporter subtypes EAAT4 and EAATs 1-3 transport glutamate with dramatically different kinetics and voltage dependence but share a common uptake mechanism

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Sulfhydryl modification of cysteine mutants of a neuronal glutamate transporter reveals an inverse relationship between sodium dependent conformational changes and the glutamate-gated anion conductance

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Small-scale molecular motions accomplish glutamate uptake in human glutamate transporters

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Structure of a glutamate transporter homologue from Pyrococcus horikoshii

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Fluorometric measurements of conformational changes in glutamate transporters

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Glutamate modifies ion conduction and voltage-dependent gating of excitatory amino acid transporter-associated anion channels

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Comparison of coupled and uncoupled currents during glutamate uptake by GLT-1 transporters.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Excitatory amino acid transporters: keeping up with glutamate.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

The anion conductance of the glutamate transporter EAAC1 depends on the direction of glutamate transport

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Early intermediates in the transport cycle of the neuronal excitatory amino acid carrier EAAC1

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Functional diversity of excitatory amino acid transporters: ion channel and transport modes.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Single-channel characteristics of wild-type IKs channels and channels formed with two minK mutants that cause long QT syndrome

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Pore-forming segments in voltage-gated chloride channels

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

A mutation in autosomal dominant myotonia congenita affects pore properties of the muscle chloride channel

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

An excitatory amino-acid transporter with properties of a ligand-gated chloride channel

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

The size of gating charge in wild-type and mutant Shaker potassium channels

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

The glial cell glutamate uptake carrier countertransports pH-changing anions

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Ion channels. Analysis of nonstationary single-channel currents

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Mutations in transmembrane domains 5 and 7 of the human excitatory amino acid transporter 1 affect the substrate-activated anion channel

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Structure and function of prokaryotic glutamate transporters from Escherichia coli and Pyrococcus horikoshii

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

The chloride permeation pathway of a glutamate transporter and its proximity to the glutamate translocation pathway.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

Ion fluxes associated with excitatory amino acid transport.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911312

The uncoupled chloride conductance of a bacterial glutamate transporter homolog

16 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M110.126557

K+ channels close more slowly in the presence of external K+ and Rb+

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M110.126557

Evidence for voltage-dependent S4 movement in sodium channels

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20519505

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.126557

1 reference

4 November 2017

1 reference

4 November 2017

PubMed publication ID

20519505

1 reference