Secretory pathways generating immunosuppressive NKG2D ligands: New targets for therapeutic intervention. (Q42702237)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25050215%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

Secretory pathways generating immunosuppressive NKG2D ligands: New targets for therapeutic intervention (English)

1 reference

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10 March 2020

author

Aroa Baragaño Raneros

series ordinal

1

1 reference

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10 March 2020

Carlos López-Larrea

series ordinal

3

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10 March 2020

author name string

Beatriz Suarez-Álvarez

series ordinal

2

1 reference

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10 March 2020

publication date

25 April 2014

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10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25050215%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

volume

3

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10 March 2020

page(s)

e28497

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25050215%20AND%20SRC:MED&resulttype=core&format=json

New prospects on the NKG2D/NKG2DL system for oncology

10 March 2020

cites work

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27 May 2018

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27 May 2018

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Hypoxia induces escape from innate immunity in cancer cells via increased expression of ADAM10: role of nitric oxide

27 May 2018

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Palmitoylation of MICA, a ligand for NKG2D, mediates its recruitment to membrane microdomains and promotes its shedding

27 May 2018

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27 May 2018

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Combinatorial cytotoxicity of gemcitabine and cytokine-activated killer cells in hepatocellular carcinoma via the NKG2D-MICA/B system.

27 May 2018

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Upregulation of NKG2D ligands and enhanced natural killer cell cytotoxicity by hydralazine and valproate.

27 May 2018

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27 May 2018

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Major histocompatibility complex class I-related chain A/B (MICA/B) expression in tumor tissue and serum of pancreatic cancer: role of uric acid accumulation in gemcitabine-induced MICA/B expression

27 May 2018

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Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells

27 May 2018

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Novel role for STAT3 in transcriptional regulation of NK immune cell targeting receptor MICA on cancer cells

27 May 2018

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Exosomes and cancer: a newly described pathway of immune suppression

27 May 2018

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MMP9 mediates MICA shedding in human osteosarcomas

27 May 2018

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The human cytomegalovirus microRNA miR-UL112 acts synergistically with a cellular microRNA to escape immune elimination

27 May 2018

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Roles of GRP78 in physiology and cancer

27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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27 May 2018

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Natural killer cell cytotoxicity is suppressed by exposure to the human NKG2D ligand MICA*008 that is shed by tumor cells in exosomes

27 May 2018

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ULBP6/RAET1L is an additional human NKG2D ligand

27 May 2018

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Tumour-experienced T cells promote NK cell activity through trogocytosis of NKG2D and NKp46 ligands

27 May 2018

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Dendritic cell-derived exosomes promote natural killer cell activation and proliferation: a role for NKG2D ligands and IL-15Ralpha

27 May 2018

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Cellular expression, trafficking, and function of two isoforms of human ULBP5/RAET1G.

27 May 2018

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Obstructing shedding of the immunostimulatory MHC class I chain-related gene B prevents tumor formation

27 May 2018

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Cutting edge: the metalloproteinase ADAM17/TNF-alpha-converting enzyme regulates proteolytic shedding of the MHC class I-related chain B protein

27 May 2018

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Cutting edge: down-regulation of MHC class I-related chain A on tumor cells by IFN-gamma-induced microRNA

27 May 2018

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Interferon-gamma down-regulates NKG2D ligand expression and impairs the NKG2D-mediated cytolysis of MHC class I-deficient melanoma by natural killer cells

27 May 2018

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Human microRNAs regulate stress-induced immune responses mediated by the receptor NKG2D.

27 May 2018

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Tumor-associated MICA is shed by ADAM proteases

27 May 2018

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Human tumor-derived exosomes down-modulate NKG2D expression.

27 May 2018

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27 May 2018

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27 May 2018

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Augmented serum level of major histocompatibility complex class I-related chain A (MICA) protein and reduced NKG2D expression on NK and T cells in patients with cervical cancer and precursor lesions

27 May 2018

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Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands.

27 May 2018

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RAET1E2, a soluble isoform of the UL16-binding protein RAET1E produced by tumor cells, inhibits NKG2D-mediated NK cytotoxicity

27 May 2018

1 reference

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Trogocytosis-based generation of suppressive NK cells

27 May 2018

1 reference

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Transcriptional regulation of ULBP1, a human ligand of the NKG2D receptor

27 May 2018

1 reference

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TGF-beta and metalloproteinases differentially suppress NKG2D ligand surface expression on malignant glioma cells

27 May 2018

1 reference

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Transfer of NKG2D and MICB at the cytotoxic NK cell immune synapse correlates with a reduction in NK cell cytotoxic function

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063154

Immunobiology of human NKG2D and its ligands

27 May 2018

1 reference

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Downregulation and/or release of NKG2D ligands as immune evasion strategy of human neuroblastoma

27 May 2018

1 reference

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TGF-beta-induced upregulation of MMP-2 and MMP-9 depends on p38 MAPK, but not ERK signaling in MCF10A human breast epithelial cells

27 May 2018

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Metalloproteinase inhibitors: biological actions and therapeutic opportunities.

27 May 2018

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A GPI anchor explains the unique biological features of the common NKG2D-ligand allele MICA*008.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4063154

Diagnostic and prognostic impact of serum-soluble UL16-binding protein 2 in lung cancer patients.

16 August 2018

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High ERp5/ADAM10 expression in lymph node microenvironment and impaired NKG2D ligands recognition in Hodgkin lymphomas.

16 August 2018

1 reference

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Clinical significance of serum levels of immune-associated molecules, uric acid and soluble MHC class I chain-related molecules A and B, as diagnostic tumor markers for pancreatic ductal adenocarcinoma.

16 August 2018

1 reference

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Clinical significance of the immunostimulatory MHC class I chain-related molecule A and NKG2D receptor on NK cells in pancreatic cancer

16 August 2018

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Anticancer chemotherapy inhibits MHC class I-related chain a ectodomain shedding by downregulating ADAM10 expression in hepatocellular carcinoma

16 August 2018

1 reference

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Differential clinical significance of individual NKG2D ligands in melanoma: soluble ULBP2 as an indicator of poor prognosis superior to S100B.

16 August 2018

1 reference

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Proteolytic release of soluble UL16-binding protein 2 from tumor cells

16 August 2018

1 reference

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BCR/ABL promotes dendritic cell-mediated natural killer cell activation

16 August 2018

1 reference

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Cutting Edge: Down-Regulation of MICA on Human Tumors by Proteolytic Shedding

16 August 2018

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Crossref

https://api.crossref.org/works/10.4161%2FONCI.28497

Functional expression and release of ligands for the activating immunoreceptor NKG2D in leukemia

21 January 2018

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Crossref

https://api.crossref.org/works/10.4161%2FONCI.28497

Serum soluble MICB (sMICB) correlates with disease progression and survival in melanoma patients

21 January 2018

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12 December 2020

The prognostic significance of soluble NKG2D ligands in B-cell chronic lymphocytic leukemia

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12 December 2020

Expression of ERp5 and GRP78 on the membrane of chronic lymphocytic leukemia cells: association with soluble MICA shedding

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12 December 2020

Soluble MICB serum levels correlate with disease stage and survival rate in patients with oral squamous cell carcinoma

1 reference

12 December 2020

Major histocompatibility complex class I-related chain A and UL16-binding protein expression on tumor cell lines of different histotypes: analysis of tumor susceptibility to NKG2D-dependent natural killer cell cytotoxicity

1 reference

12 December 2020

Impairment of natural killer cell and dendritic cell functions by the soluble form of MHC class I-related chain A in advanced human hepatocellular carcinomas

1 reference

12 December 2020

Soluble MICA as an independent prognostic factor for the overall survival and progression-free survival of multiple myeloma patients

1 reference

12 December 2020

Post-transcriptional regulation of ULBP1 ligand for the activating immunoreceptor NKG2D involves 3' untranslated region

1 reference

12 December 2020

Identifiers

DOI

10.4161/ONCI.28497

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25050215%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25050215%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25050215%20AND%20SRC:MED&resulttype=core&format=json