The Akt inhibitor KP372-1 suppresses Akt activity and cell proliferation and induces apoptosis in thyroid cancer cells. (Q42705524)

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11 January 2020

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29 December 2023

https://doi.org/10.1038/s41416-021-01299-9

title

The Akt inhibitor KP372-1 suppresses Akt activity and cell proliferation and induces apoptosis in thyroid cancer cells (English)

1 reference

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11 January 2020

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1

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11 January 2020

author name string

S Kim

2

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11 January 2020

M N Younes

3

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S A Jasser

4

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11 January 2020

A K El-Naggar

5

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11 January 2020

G B Mills

6

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11 January 2020

J N Myers

7

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11 January 2020

language of work or name

English

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publication date

1 May 2005

1 reference

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British Journal of Cancer

11 January 2020

published in

1 reference

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volume

92

1 reference

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issue

10

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11 January 2020

page(s)

1899-1905

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Akt activation and localisation correlate with tumour invasion and oncogene expression in thyroid cancer

11 January 2020

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Suppression of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated aryl hydrocarbon receptor transformation and CYP1A1 induction by the phosphatidylinositol 3-kinase inhibitor 2-(4-morpholinyl)-8-phenyl-4H-1- benzopyran-4-one (LY294002).

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Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor.

27 May 2018

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Phosphatidylinositol 3-kinase, protein kinase B and ribosomal S6 kinases in the stimulation of thyroid epithelial cell proliferation by cAMP and growth factors in the presence of insulin

27 May 2018

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Insulin and TSH promote growth in size of PC Cl3 rat thyroid cells, possibly via a pathway different from DNA synthesis: comparison with FRTL-5 cells

27 May 2018

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27 May 2018

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Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

27 May 2018

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The oncogenic versions of the Ret and Trk tyrosine kinases bind Shc and Grb2 adaptor proteins

27 May 2018

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Phosphatidylinositol-3-OH kinase as a direct target of Ras

27 May 2018

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A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

27 May 2018

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Inhibition of the phosphatidylinositol 3'-kinase-AKT pathway induces apoptosis in pancreatic carcinoma cells in vitro and in vivo

27 May 2018

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BCR-ABL gene mutations in relation to clinical resistance of Philadelphia-chromosome-positive leukaemia to STI571: a prospective study

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Bcl-2 Prevents CD95 (Fas/APO-1)-induced Degradation of Lamin B and Poly(ADP-ribose) Polymerase and Restores the NF-κB Signaling Pathway

16 August 2018

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Crossref

https://api.crossref.org/works/10.1038%2FSJ.BJC.6602595

Overexpression and overactivation of Akt in thyroid carcinoma

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15870708

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/SJ.BJC.6602595

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15870708%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15870708%20AND%20SRC:MED&resulttype=core&format=json

11 January 2020

PubMed publication ID

15870708

1 reference