Aberrantly activated EGFR contributes to enhanced IL-8 expression in COPD airways epithelial cells via regulation of nuclear FoxO3A. (Q42715110)

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title

Aberrantly activated EGFR contributes to enhanced IL-8 expression in COPD airways epithelial cells via regulation of nuclear FoxO3A (English)

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1

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Peter Mancuso

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Fernando J Martinez

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author name string

Benjamin L Unger

2

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Adam T Comstock

3

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Kristen A Angel

4

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Umadevi S Sajjan

7

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language of work or name

English

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publication date

25 October 2012

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volume

68

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page(s)

131-141

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issue

2

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Bacterial endotoxin is an active component of cigarette smoke

16 February 2020

cites work

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12 December 2020

New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway

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IkappaB kinases alpha and beta show a random sequential kinetic mechanism and are inhibited by staurosporine and quercetin

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Effects of luteolin and quercetin, inhibitors of tyrosine kinase, on cell growth and metastasis-associated properties in A431 cells overexpressing epidermal growth factor receptor

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Epidermal growth factor receptor-dependent Akt activation by oxidative stress enhances cell survival

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Oxidants/antioxidants and COPD.

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

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Nicotine-induced phosphorylation of Akt through epidermal growth factor receptor and Src in PC12h cells

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Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells

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Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

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Tobacco smoke control of mucin production in lung cells requires oxygen radicals AP-1 and JNK.

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12 December 2020

Regulation of NF-kappaB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a

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12 December 2020

Regulation of FoxO activity by CBP/p300-mediated acetylation.

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12 December 2020

Cigarette smoke synergistically enhances respiratory mucin induction by proinflammatory stimuli

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12 December 2020

Elevated concentrations of endotoxin in indoor air due to cigarette smoking

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12 December 2020

Quercetin blocks airway epithelial cell chemokine expression

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12 December 2020

Inhibition of forkhead box class O family member transcription factors in rheumatoid synovial tissue

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12 December 2020

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12 December 2020

Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells

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12 December 2020

The transcription of FOXO genes is stimulated by FOXO3 and repressed by growth factors

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12 December 2020

Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells

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12 December 2020

Deregulation of FOXO3A during prostate cancer progression

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12 December 2020

LPS-stimulated MUC5AC production involves Rac1-dependent MMP-9 secretion and activation in NCI-H292 cells

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12 December 2020

Tumor suppressor FOXO3 participates in the regulation of intestinal inflammation

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12 December 2020

Elastase- and LPS-exposed mice display altered responses to rhinovirus infection

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12 December 2020

Targeting phosphoinositide-3-kinase-delta with theophylline reverses corticosteroid insensitivity in chronic obstructive pulmonary disease.

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12 December 2020

Increased cytokine response of rhinovirus-infected airway epithelial cells in chronic obstructive pulmonary disease

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12 December 2020

Forkhead homeobox type O transcription factors in the responses to oxidative stress

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12 December 2020

Highly specialized role of Forkhead box O transcription factors in the immune system.

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12 December 2020

Quercetin prevents progression of disease in elastase/LPS-exposed mice by negatively regulating MMP expression

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12 December 2020

Rhinovirus-induced barrier dysfunction in polarized airway epithelial cells is mediated by NADPH oxidase 1.

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12 December 2020

Regulation of cigarette smoke-mediated mucin expression by hypoxia-inducible factor-1α via epidermal growth factor receptor-mediated signaling pathways

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12 December 2020

FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary disease

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12 December 2020

Novel outcomes and end points: biomarkers in chronic obstructive pulmonary disease clinical trials

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12 December 2020

Elastase/LPS-exposed mice exhibit impaired innate immune responses to bacterial challenge: role of scavenger receptor A.

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12 December 2020

Relationship between flavonoid structure and inhibition of phosphatidylinositol 3-kinase: a comparison with tyrosine kinase and protein kinase C inhibition.

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12 December 2020

10.1136/THORAXJNL-2012-201719

Identifiers

DOI

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