Pharmacological separation of early afterdepolarizations from arrhythmogenic substrate in DeltaKPQ Scn5a murine hearts modelling human long QT 3 syndrome (Q42729116)

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scientific article published on 31 October 2007

Language	Label	Description	Also known as
English	Pharmacological separation of early afterdepolarizations from arrhythmogenic substrate in DeltaKPQ Scn5a murine hearts modelling human long QT 3 syndrome	scientific article published on 31 October 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

Pharmacological separation of early afterdepolarizations from arrhythmogenic substrate in DeltaKPQ Scn5a murine hearts modelling human long QT 3 syndrome (English)

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

1 reference

based on heuristic

inferred from title

author name string

G Thomas

1

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

M J Killeen

2

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

A A Grace

3

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

C L-H Huang

4

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

publication date

31 October 2007

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Europe PubMed Central

PMC publication ID

5 November 2017

Acta Physiologica

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Europe PubMed Central

PMC publication ID

5 November 2017

192

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Europe PubMed Central

PMC publication ID

5 November 2017

4

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

505-517

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

Separation of early afterdepolarizations from arrhythmogenic substrate in the isolated perfused hypokalaemic murine heart through modifiers of calcium homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Arrhythmogenic mechanisms in the isolated perfused hypokalaemic murine heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Optical mapping of ventricular arrhythmias in LQTS mice with SCN5A mutation N1325S

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Paced electrogram fractionation analysis of arrhythmogenic tendency in DeltaKPQ Scn5a mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Association of long QT syndrome loci and cardiac events among patients treated with beta-blockers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Electrogram prolongation and nifedipine-suppressible ventricular arrhythmias in mice following targeted disruption of KCNE1

1 reference

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27 May 2018

Possible bradycardic mode of death and successful pacemaker treatment in a large family with features of long QT syndrome type 3 and Brugada syndrome

1 reference

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27 May 2018

Cellular and ionic mechanisms responsible for the Brugada syndrome

1 reference

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27 May 2018

Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Progress in the understanding of cardiac early afterdepolarizations and torsades de pointes: time to revise current concepts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Differential effects of beta-adrenergic agonists and antagonists in LQT1, LQT2 and LQT3 models of the long QT syndrome.

1 reference

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27 May 2018

Effectiveness and limitations of beta-blocker therapy in congenital long-QT syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Experimental models of torsade de pointes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Management of patients with the hereditary long QT syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Cellular basis for QT dispersion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Cardiac sodium channel mutations in patients with long QT syndrome, an inherited cardiac arrhythmia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Early afterdepolarizations in cardiac myocytes: mechanism and rate dependence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Electrophysiologic actions of high plasma concentrations of propranolol in human subjects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Effects of propranolol and a number of its analogues on sodium channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Effects of propranolol on the transmembrane potentials of ventricular muscle and Purkinje fibers of the dog.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Early afterdepolarizations: mechanism of induction and block. A role for L-type Ca2+ current

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Sodium channel block produces opposite electrophysiological effects in canine ventricular epicardium and endocardium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Ventricular fibrillation in hypertrophic cardiomyopathy is associated with increased fractionation of paced right ventricular electrograms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

Relationship of nonspecific antiarrhythmic and negative inotropic activity with physicochemical parameters of propranolol analogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

27 May 2018

A quantitative analysis of the effect of cycle length on arrhythmogenicity in hypokalaemic Langendorff-perfused murine hearts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

16 August 2018

Effects of L-type Ca2+ channel antagonism on ventricular arrhythmogenesis in murine hearts containing a modification in the Scn5a gene modelling human long QT syndrome 3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

16 August 2018

Mechanisms of ventricular arrhythmogenesis in mice following targeted disruption of KCNE1 modelling long QT syndrome 5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

16 August 2018

Mechanisms underlying variations in excitation-contraction coupling across the mouse left ventricular free wall

1 reference

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16 August 2018

Cellular and ionic mechanism for drug-induced long QT syndrome and effectiveness of verapamil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

16 August 2018

Spatial dispersion of repolarization is a key factor in the arrhythmogenicity of long QT syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

16 August 2018

Implications of ventricular arrhythmia vulnerability during murine electrophysiology studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

16 August 2018

Effect of pacing and mexiletine on dispersion of repolarisation and arrhythmias in DeltaKPQ SCN5A (long QT3) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

16 August 2018

Prolonged action potential durations, increased dispersion of repolarization, and polymorphic ventricular tachycardia in a mouse model of proarrhythmia

1 reference

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16 August 2018

Abrupt rate accelerations or premature beats cause life-threatening arrhythmias in mice with long-QT3 syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

16 August 2018

Action potential characteristics and arrhythmogenic properties of the cardiac conduction system of the murine heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268972

16 August 2018

Phase 2 early afterdepolarization as a trigger of polymorphic ventricular tachycardia in acquired long-QT syndrome : direct evidence from intracellular recordings in the intact left ventricular wall

1 reference

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16 August 2018

Electrotonic suppression of early afterdepolarizations in isolated rabbit Purkinje myocytes.

1 reference

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16 August 2018

Enhanced dispersion of repolarization and refractoriness in transgenic mouse hearts promotes reentrant ventricular tachycardia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17973950

12 December 2020

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inferred from PubMed ID database lookup

Monophasic action potential recordings from intact mouse heart: validation, regional heterogeneity, and relation to refractoriness

1 reference

https://pubmed.ncbi.nlm.nih.gov/17973950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of endogenous catecholamines and norepinephrine administration on the performance of the isolated canine heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/17973950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of chronic ventricular arrhythmias with propranolol

1 reference

https://pubmed.ncbi.nlm.nih.gov/17973950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Propranolol effects on membrane repolarization time in isolated canine Purkinje fibers: threshold tissue content and the influence of exposure time

1 reference

https://pubmed.ncbi.nlm.nih.gov/17973950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of pacing on triggered activity induced by early afterdepolarizations

1 reference

https://pubmed.ncbi.nlm.nih.gov/17973950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sudden death risk in overt coronary heart disease: the Framingham Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17973950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circadian variation in the incidence of sudden cardiac death in the Framingham Heart Study population

1 reference

https://pubmed.ncbi.nlm.nih.gov/17973950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of Torsades de Pointes with verapamil in patients with atrio-ventricular block

1 reference

https://pubmed.ncbi.nlm.nih.gov/17973950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differences in the electrophysiological response of canine ventricular epicardium and endocardium to ischemia. Role of the transient outward current

1 reference

https://pubmed.ncbi.nlm.nih.gov/17973950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous catecholamines are not necessary for ischaemic preconditioning in the isolated perfused rat heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/17973950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transmural dispersion in LQT3 and arrhythmogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17973950

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based on heuristic

inferred from PubMed ID database lookup

Effects of flecainide and quinidine on arrhythmogenic properties of Scn5a+/Delta murine hearts modelling long QT syndrome 3

1 reference

https://pubmed.ncbi.nlm.nih.gov/17973950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dispersion of repolarization and refractoriness are determinants of arrhythmia phenotype in transgenic mice with long QT

1 reference

https://pubmed.ncbi.nlm.nih.gov/17973950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repolarization gradients and arrhythmogenicity in the murine heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/17973950

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1748-1716.2007.01770.X

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

5 November 2017

ResearchGate publication ID

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