Sphingosine-1-Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic Preconditioning (Q42746435)

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English	Sphingosine-1-Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic Preconditioning	scientific article

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6 November 2017

Sphingosine-1-Phosphate Receptor 1 Regulates Cardiac Function by Modulating Ca2+ Sensitivity and Na+/H+ Exchange and Mediates Protection by Ischemic Preconditioning (English)

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6 November 2017

Jan Sebastian Schulte

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6 June 2020

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6 June 2020

Arie O. Verkerk

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6 June 2020

Wolfgang A Linke

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Wolfgang A Linke

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Petra Keul

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6 June 2020

Marcel M G J van Borren

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6 June 2020

Alexander Ghanem

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6 June 2020

Frank Ulrich Müller

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6 June 2020

Antonius Baartscheer

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6 June 2020

Frank Stümpel

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6 June 2020

Nazha Hamdani

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6 June 2020

Pieter van Loenen

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6 June 2020

Marek Matus

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6 June 2020

Wilhelm Schmitz

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6 June 2020

Jörg Stypmann

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6 June 2020

Klaus Tiemann

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6 June 2020

Jan-Hindrik Ravesloot

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6 June 2020

Astrid E Alewijnse

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6 June 2020

Sven Hermann

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6 June 2020

Léon J A Spijkers

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6 June 2020

Karl-Heinz Hiller

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6 June 2020

Gerd Heusch

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6 June 2020

Michael Schäfers

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6 June 2020

Stephan L M Peters

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6 June 2020

Jerold Chun

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6 June 2020

Bodo Levkau

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6 June 2020

publication date

20 May 2016

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6 November 2017

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease

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6 June 2020

5

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6 June 2020

5

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6 June 2020

Sphingosine-1-Phosphate Receptor Agonist Fingolimod Increases Myocardial Salvage and Decreases Adverse Postinfarction Left Ventricular Remodeling in a Porcine Model of Ischemia/Reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

HDL-S1P: cardiovascular functions, disease-associated alterations, and therapeutic applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

Immunosuppression With FTY720 Reverses Cardiac Dysfunction in Hypomorphic ApoE Mice Deficient in SR-BI Expression That Survive Myocardial Infarction Caused by Coronary Atherosclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

The relationship between the high-density lipoprotein (HDL)-associated sphingosine-1-phosphate (S1P) and coronary in-stent restenosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

Molecular basis of cardioprotection: signal transduction in ischemic pre-, post-, and remote conditioning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

The immunosuppressant FTY720 prolongs survival in a mouse model of diet-induced coronary atherosclerosis and myocardial infarction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

β1-adrenergic receptor and sphingosine-1-phosphate receptor 1 (S1PR1) reciprocal downregulation influences cardiac hypertrophic response and progression to heart failure: protective role of S1PR1 cardiac gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

Serum sphingolipids level as a novel potential marker for early detection of human myocardial ischaemic injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

Cardiovascular effects of sphingosine-1-phosphate (S1P).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

S1P, dihydro-S1P and C24:1-ceramide levels in the HDL-containing fraction of serum inversely correlate with occurrence of ischemic heart disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

Sphingosine 1-phosphate is an important endogenous cardioprotectant released by ischemic pre- and postconditioning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

Sphingosine-1-phosphate receptor signalling in the heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

Sphingosine kinase and sphingosine 1-phosphate in cardioprotection

1 reference

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27 May 2018

Gene variants associated with ischemic stroke: the cardiovascular health study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

Survivin determines cardiac function by controlling total cardiomyocyte number

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

S1P1 receptor localization confers selectivity for Gi-mediated cAMP and contractile responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

Signal transduction and Ca2+ signaling in intact myocardium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.

1 reference

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27 May 2018

Sphingosine 1-phosphate stimulates Na+/H+ exchange in thyroid FRTL-5 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

27 May 2018

Molecular physiology of vertebrate Na+/H+ exchangers

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27 May 2018

Defects of High-Density Lipoproteins in Coronary Artery Disease Caused by Low Sphingosine-1-Phosphate Content: Correction by Sphingosine-1-Phosphate-Loading

1 reference

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16 August 2018

Deranged myofilament phosphorylation and function in experimental heart failure with preserved ejection fraction

1 reference

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16 August 2018

Sphingosine 1-phosphate levels in plasma and HDL are altered in coronary artery disease

1 reference

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16 August 2018

Pushing and pulling the cardiac sodium/hydrogen exchanger

1 reference

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16 August 2018

Activation of Na+/H+ exchanger 1 is sufficient to generate Ca2+ signals that induce cardiac hypertrophy and heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

16 August 2018

Mechanisms of the negative inotropic effects of sphingosine-1-phosphate on adult mouse ventricular myocytes.

1 reference

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16 August 2018

Sphingosine 1-phosphate S1P2 and S1P3 receptor-mediated Akt activation protects against in vivo myocardial ischemia-reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

16 August 2018

Sphingosine kinase activation mediates ischemic preconditioning in murine heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

16 August 2018

Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4889204

16 August 2018

No ischemic preconditioning in heterozygous connexin43-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/27207969

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HDL-bound sphingosine 1-phosphate (S1P) predicts the severity of coronary artery atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/27207969

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-density lipoproteins and their constituent, sphingosine-1-phosphate, directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/27207969

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1161/JAHA.116.003393

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27207969%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

PMC publication ID

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6 June 2020

PubMed publication ID

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27207969%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

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