Mitochondrial damage: a possible mechanism of the "topical" phase of NSAID induced injury to the rat intestine (Q42747553)

6 November 2017

Mitochondrial damage: a possible mechanism of the "topical" phase of NSAID induced injury to the rat intestine (English)

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6 November 2017

S Somasundaram

1

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6 November 2017

S Rafi

2

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6 November 2017

J Hayllar

3

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6 November 2017

G Sigthorsson

4

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6 November 2017

M Jacob

5

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6 November 2017

A B Price

6

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6 November 2017

A Macpherson

7

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6 November 2017

T Mahmod

8

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6 November 2017

D Scott

9

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6 November 2017

J M Wrigglesworth

10

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6 November 2017

I Bjarnason

11

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6 November 2017

language of work or name

English

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publication date

1 September 1997

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6 November 2017

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6 November 2017

41

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6 November 2017

3

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6 November 2017

344-353

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Protein measurement with the Folin phenol reagent

6 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Novel nonsteroidal anti-inflammatory drug derivatives with markedly reduced ulcerogenic properties in the rat

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

The 1994 Merck Frosst Award. Mechanisms of nonsteroidal anti-inflammatory drug (NSAID) induced gastrointestinal damage--potential for development of gastrointestinal tract safe NSAIDs

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Review: The Biochemical Basis of Non-Steroidal Anti-Inflammatory Drug-Induced Damage to the Gastrointestinal Tract: A Review and a Hypothesis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Non-steroidal anti-inflammatory drugs (NSAIDs) associate with zwitterionic phospholipids: Insight into the mechanism and reversal of NSAID-induced gastrointestinal injury

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Investigation of tissue organelles by a combination of analytical subcellular fractionation and enzymic microanalysis: a new approach to pathology

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Ultrastructural observations on the pathogenesis of aspirin-induced gastric erosions.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Aspirin- and taurocholate-induced metabolic damage in mammalian gastric mucosa in vitro

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Anti-inflammatory/anti-pyretic salicylic acid esters with low gastric ulcerogenic activity

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Small intestinal ulcers and intestinal flora in rats given indomethacin

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Indomethacin-induced intestinal lesions in the rat

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Effect of non-steroidal anti-inflammatory drugs and prostaglandins on the permeability of the human small intestine

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Recent insight into the mechanism of gastrointestinal tract ulceration

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Intracellular calcium homeostasis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Mechanisms of gastrointestinal toxicity of non-steroidal anti-inflammatory drugs

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Non-steroidal anti-inflammatory drug-induced gastropathy. Mechanisms and management

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Abolition by omeprazole of aspirin induced gastric mucosal injury in man.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Nonsteroidal antiinflammatory drugs--differences and similarities

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Importance of local versus systemic effects of non-steroidal anti-inflammatory drugs in increasing small intestinal permeability in man

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Injury-induced inhibition of small intestinal protein and nucleic acid synthesis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Mechanisms underlying gastric mucosal damage induced by indomethacin and bile-salts, and the actions of prostaglandins

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Prostaglandin and cimetidine inhibit the formation of ulcers produced by parenteral salicylates

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Effect of acetylsalicylic acid on gastric mucosa. II. Mucosal ATP and phosphocreatine content, and salicylate effects on mitochondrial metabolism

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

In vitro effects of nonsteroidal anti-inflammatory drugs on oxidative phosphorylation in rat liver mitochondria

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Gastric Mucosal Lesions Produced by Intravenous Infusion of Aspirin in Cats

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Effects of nonsteroidal, antiinflammatory drugs on gastrointestinal injury and prostanoid generation in healthy volunteers

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

Chemical hypoxia increases junctional permeability and activates electrogenic ion transport in human intestinal epithelial monolayers.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891477

NSAIDs, Cox-2 inhibitors, and the gut

16 August 2018

1 reference

12 December 2020

BIOCHEMICAL PROPERTIES OF ANTI-INFLAMMATORY DRUGS--III. UNCOUPLING OF OXIDATIVE PHOSPHORYLATION IN A CONNECTIVE TISSUE (CARTILAGE) AND LIVER MITOCHONDRIA BY SALICYLATE ANALOGUES: RELATIONSHIP OF STRUCTURE TO ACTIVITY

1 reference

12 December 2020

Analytical subcellular fractionation of jejunal biopsy specimens: enzyme activities, organelle pathology and response to corticosteroids in patients with non-responsive coeliac disease

1 reference

12 December 2020

Parietal cells of the stomach trap salicylates during absorption

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12 December 2020

Acute effect of systemic aspirin on gastric mucosa in man

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12 December 2020

The respiratory chain and oxidative phosphorylation

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12 December 2020

Endogenous gastric mucosal prostaglandins: their role in mucosal integrity

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12 December 2020

Early histological features of small intestinal injury induced by indomethacin

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12 December 2020

Relationship of the Enterohepatic Cycle to Ulcerogenesis in the Rat Small Bowel with Flufenamic Acid

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12 December 2020

New understandings of NSAID gastropathy

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12 December 2020

A Possible Basis for the Anti-inflammatory Activity of Salicylates and other Non-Hormonal Anti-Rheumatic Drugs

1 reference

12 December 2020

Effects of anionic surfactants on hamster small intestinal membrane structure and function: relationship to surface activity

1 reference

12 December 2020

Aspirin can inhibit gastric mucosal cyclo-oxygenase without causing lesions in rat

1 reference

12 December 2020

Aspirin-induced ultrastructural changes in human gastric mucosa: correlation with potential difference

1 reference

12 December 2020

Misoprostol reduces indomethacin-induced changes in human small intestinal permeability

1 reference

12 December 2020

Controversies in the detection and management of nonsteroidal antiinflammatory drug-induced side effects of the upper gastrointestinal tract

1 reference

12 December 2020

Laxative-like effects of nonsteroidal anti-inflammatory drugs on intestinal fluid movement and membrane integrity

1 reference

12 December 2020

Antiinflammatory and gastrointestinal effects of nabumetone or its active metabolite, 6-methoxy-2-naphthylacetic acid (6MNA). Comparative studies with indomethacin

1 reference

12 December 2020

Biochemical gastroprotection from acute ulceration induced by aspirin and related drugs

1 reference

12 December 2020

Oxidative phosphorylation and respiration by rat liver mitochondria from aspirin-treated rats

1 reference

12 December 2020

Inactivation of rat small intestinal brush-border membrane alkaline phosphatase by oxygen free radicals

1 reference

12 December 2020

Identifiers

DOI

10.1136/GUT.41.3.344

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6 November 2017

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6 November 2017

PubMed publication ID

9378390

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