Inhibiting lung lining fluid glutathione metabolism with GGsTop as a novel treatment for asthma. (Q42759041)

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12 March 2020

title

Inhibiting lung lining fluid glutathione metabolism with GGsTop as a novel treatment for asthma (English)

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12 March 2020

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7

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12 March 2020

author name string

Marina Tuzova

1

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12 March 2020

Jyh-Chang Jean

2

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12 March 2020

Rebecca P Hughey

3

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12 March 2020

Lou Ann S Brown

4

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12 March 2020

William W Cruikshank

5

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12 March 2020

Jun Hiratake

6

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12 March 2020

publication date

31 July 2014

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Frontiers in Pharmacology

12 March 2020

published in

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volume

5

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12 March 2020

page(s)

179

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Contribution by polymorphonucleate granulocytes to elevated gamma-glutamyltransferase in cystic fibrosis sputum

12 March 2020

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Gamma-glutamyl transpeptidase-deficient mice are resistant to the nephrotoxic effects of cisplatin

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Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

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Requirement for IL-13 independently of IL-4 in experimental asthma

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A Phase I and pharmacological study of the glutamine antagonist acivicin with the amino acid solution aminosyn in patients with advanced solid malignancies

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gamma-Glutamyl transpeptidase, a glutathionase: its expression and function in carcinogenesis

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Pulmonary oxidative stress response in young children with cystic fibrosis

27 May 2018

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Nitrogen dioxide exposure activates gamma-glutamyl transferase gene expression in rat lung.

27 May 2018

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Mice with genetic gamma-glutamyl transpeptidase deficiency exhibit glutathionuria, severe growth failure, reduced life spans, and infertility

27 May 2018

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27 May 2018

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Alveolar lining layer is thin and continuous: low-temperature scanning electron microscopy of rat lung

27 May 2018

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27 May 2018

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Glutathione metabolism in the lung: inhibition of its synthesis leads to lamellar body and mitochondrial defects

27 May 2018

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27 May 2018

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Crossref

https://api.crossref.org/works/10.3389%2FFPHAR.2014.00179

Normal alveolar epithelial lining fluid contains high levels of glutathione

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12 December 2020

Synthesis and release of amphipathic gamma-glutamyl transferase by the pulmonary alveolar type 2 cell. Its redistribution throughout the gas exchange portion of the lung indicates a new role for surfactant

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12 December 2020

Glutathione turnover is increased during the acute phase of sepsis in rats

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12 December 2020

gamma-Glutamyl transferase (GGT) deficiency in the GGTenu1 mouse results from a single point mutation that leads to a stop codon in the first coding exon of GGT mRNA

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12 December 2020

Increased levels of glutathione in bronchoalveolar lavage fluid from patients with asthma

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12 December 2020

Gamma-(monophenyl)phosphono glutamate analogues as mechanism-based inhibitors of gamma-glutamyl transpeptidase

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12 December 2020

Preventive effect of GGsTop, a novel and selective γ-glutamyl transpeptidase inhibitor, on ischemia/reperfusion-induced renal injury in rats

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12 December 2020

Identifiers

DOI

10.3389/FPHAR.2014.00179

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25132819%20AND%20SRC:MED&resulttype=core&format=json

12 March 2020

1 reference

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12 March 2020

PubMed publication ID

25132819

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25132819%20AND%20SRC:MED&resulttype=core&format=json