Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells. (Q42775682)

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21 February 2020

title

Megakaryocytes maintain homeostatic quiescence and promote post-injury regeneration of hematopoietic stem cells (English)

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21 February 2020

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8

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21 February 2020

author name string

Meng Zhao

1

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21 February 2020

John M Perry

2

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21 February 2020

Heather Marshall

3

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21 February 2020

Aparna Venkatraman

4

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21 February 2020

Pengxu Qian

5

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21 February 2020

Xi C He

6

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21 February 2020

Jasimuddin Ahamed

7

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21 February 2020

language of work or name

English

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publication date

19 October 2014

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21 February 2020

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21 February 2020

volume

20

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21 February 2020

issue

11

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21 February 2020

page(s)

1321-1326

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Identification of the haematopoietic stem cell niche and control of the niche size

21 February 2020

cites work

1 reference

Osteoblastic cells regulate the haematopoietic stem cell niche

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SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

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Maintenance of the hematopoietic stem cell pool by CXCL12-CXCR4 chemokine signaling in bone marrow stromal cell niches

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Mesenchymal and haematopoietic stem cells form a unique bone marrow niche

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Endothelial and perivascular cells maintain haematopoietic stem cells

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TGF-beta as a candidate bone marrow niche signal to induce hematopoietic stem cell hibernation.

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FGF signaling facilitates postinjury recovery of mouse hematopoietic system.

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FGF-2 expands murine hematopoietic stem and progenitor cells via proliferation of stromal cells, c-Kit activation, and CXCL12 down-regulation.

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Coexistence of quiescent and active adult stem cells in mammals

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Bone marrow macrophages maintain hematopoietic stem cell (HSC) niches and their depletion mobilizes HSCs.

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Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche

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CD169⁺ macrophages provide a niche promoting erythropoiesis under homeostasis and stress

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Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after marrow radioablation.

21 January 2018

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Megakaryocytes promote murine osteoblastic HSC niche expansion and stem cell engraftment after radioablative conditioning.

21 January 2018

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A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

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A Cre-inducible diphtheria toxin receptor mediates cell lineage ablation after toxin administration.

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Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients.

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IFNalpha activates dormant haematopoietic stem cells in vivo.

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Fatty acid binding protein 4 is a target of VEGF and a regulator of cell proliferation in endothelial cells.

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Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis

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TGFβ restores hematopoietic homeostasis after myelosuppressive chemotherapy.

21 January 2018

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Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells.

21 January 2018

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Cooperation between both Wnt/{beta}-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion

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Lineage tracing of Pf4-Cre marks hematopoietic stem cells and their progeny

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Generation of mice with a conditional allele for transforming growth factor beta 1 gene

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Platelet TGF-β1 contributions to plasma TGF-β1, cardiac fibrosis, and systolic dysfunction in a mouse model of pressure overload.

21 January 2018

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Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche

21 January 2018

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Differential regulation of myeloid leukemias by the bone marrow microenvironment

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In vitro generation of long-term repopulating hematopoietic stem cells by fibroblast growth factor-1

21 January 2018

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12 December 2020

Megakaryocytes regulate hematopoietic stem cell quiescence through CXCL4 secretion.

1 reference

12 December 2020

Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo

1 reference

12 December 2020

Generation of Fgfr1 conditional knockout mice

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12 December 2020

Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche

1 reference

12 December 2020