Neoantigens in complement component C3 as detected by monoclonal antibodies. Mapping of the recognized epitopes by synthetic peptides. (Q42794180)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1693076%20AND%20SRC:MED&resulttype=core&format=json

16 September 2019

title

Neoantigens in complement component C3 as detected by monoclonal antibodies. Mapping of the recognized epitopes by synthetic peptides (English)

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16 September 2019

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5

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16 September 2019

1

B Nilsson

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16 September 2019

author name string

K Nilsson Ekdahl

series ordinal

2

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16 September 2019

D Avila

series ordinal

3

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16 September 2019

U R Nilsson

series ordinal

4

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16 September 2019

language of work or name

English

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publication date

1 May 1990

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16 September 2019

number of pages

7

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inferred from page(s)

published in

Biochemical Journal

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16 September 2019

volume

268

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16 September 2019

issue

1

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16 September 2019

page(s)

55-61

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1693076%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

16 September 2019

1 reference

The binding of complement component C3 to antibody-antigen aggregates after activation of the alternative pathway in human serum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Unique role of the complement receptor CR1 in the degradation of C3b associated with immune complexes

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Covalent binding and hemolytic activity of complement proteins

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Physiologic inactivation of fluid phase C3b: isolation and structural analysis of C3c, C3d,g (alpha 2D), and C3g

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

The binding of human complement proteins C5, factor B, beta 1H and properdin to complement fragment C3b on zymosan

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Kinetic and thermodynamic analysis of the control of C3b by the complement regulatory proteins factors H and I

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Identification of functionally relevant determinants on the complement component C3 with monoclonal antibodies

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Breakdown of C3 after complement activation. Identification of a new fragment C3g, using monoclonal antibodies

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Structural analysis of the asparagine-linked oligosaccharides of human complement component C3.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Purification and characterization of a membrane protein (gp45-70) that is a cofactor for cleavage of C3b and C4b.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Detection of disulphide bonds and localization of interchain linkages in the third (C3) and the fourth (C4) components of human complement

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Molecular modelling of human complement component C3 and its fragments by solution scattering.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Membrane complement receptors specific for bound fragments of C3.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

The multifunctional role of C3, the third component of complement

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Identification of the C3b receptor-binding domain in third component of complement

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Monoclonal antibodies against complement 3 neoantigens for detection of immune complexes and complement activation. Relationship between immune complex levels, state of C3, and numbers of receptors for C3b.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Human complement component C3: cDNA coding sequence and derived primary structure

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Cell surface proteins reacting with activated complement components

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Monoclonal antibodies as probes of conformational changes in protein-engineered cytochrome c.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Influence of protein flexibility and peptide conformation on reactivity of monoclonal anti-peptide antibodies with a protein alpha-helix

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Functional and antigenic properties of complement receptor type 2, CR2.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Mapping of the C3d receptor (CR2)-binding site and a neoantigenic site in the C3d domain of the third component of complement

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

The role of C4-binding protein and {beta }1H in proteolysis of C4b and C3b

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Activation of the alternative complement pathway due to resistance of zymosan-bound amplification convertase to endogenous regulatory mechanisms

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Physico-chemical and antigenic properties of human C3

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1131390

Human C3 and C5: subunit structure and modifications by trypsin and C42-C423

27 May 2018

1 reference

12 December 2020

Characterization of tryptic fragments of human complement factor C3

1 reference

12 December 2020

Location of the inter-chain disulfide bonds of the third component of human complement

1 reference

12 December 2020

Suppression of T lymphocyte functions by human C3 fragments. I. Inhibition of human T cell proliferative responses by a kallikrein cleavage fragment of human iC3b

1 reference

12 December 2020

Selective inhibition of functional sites of cell-bound C3b by hybridoma-derived antibodies

1 reference

12 December 2020

Analogous antigenic alterations elicited in C3 by physiologic binding and by denaturation in the presence of sodium dodecylsulfate

1 reference

12 December 2020

Conformational changes accompanying proteolytic cleavage of human complement protein C3b by the regulatory enzyme factor I and its cofactor H. Spectroscopic and enzymological studies

1 reference

12 December 2020

Large scale isolation of functionally active components of the human complement system

1 reference

12 December 2020

Generation of the bioactive kallikrein-derived fragment, C3d-k, by HANE-plasma

1 reference

12 December 2020

Isolation of rabbit C3, Factor B, and Factor H and comparison of their properties with those of the human analog

1 reference

12 December 2020

The multifunctional role of C3: Structural analysis of its interactions with physiological ligands

1 reference

12 December 2020

A discontinuous factor H binding site in the third component of complement as delineated by synthetic peptides

1 reference

12 December 2020

Distinctive expression of neoantigenic C3(D) epitopes on bound C3 following activation and binding to different target surfaces in normal and pathological human sera

1 reference

12 December 2020

The C terminus of the anaphylatoxin C3a generated upon complement activation represents a neoantigenic determinant with diagnostic potential

1 reference

12 December 2020

Characterization of a Monoclonal Antibody MoAb bH6 Reacting with a Neoepitope of Human C3 Expressed on C3b, iC3b, and C3c

1 reference

12 December 2020

Characterization of three monoclonal antibodies against C3 with selective specificities

1 reference

12 December 2020

Production of mouse monoclonal antibodies that detect distinct neoantigenic epitopes on bound C3b and iC3b but not on the corresponding soluble fragments

1 reference

12 December 2020

An assessment of the extent of antigenic analogy between physiologically bound C3 and C3 denatured by sodium dodecyl sulphate

1 reference

12 December 2020

Detection of a neoantigen on human C3bi and C3d by monoclonal antibody

1 reference

12 December 2020

A 34-amino acid peptide of the third component of complement mediates properdin binding

1 reference

12 December 2020

The structure and function of the third component of human complement—I. The nature and extent of conformational changes accompanying C3 activation

1 reference

12 December 2020

Characterization of the human complement (c3b) receptor with a fluid phase C3b dimer

1 reference

12 December 2020

Identifiers

DOI

10.1042/BJ2680055

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1693076%20AND%20SRC:MED&resulttype=core&format=json

16 September 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:1693076%20AND%20SRC:MED&resulttype=core&format=json

16 September 2019

1 reference