Ras inactivation of the retinoblastoma pathway by distinct mechanisms in NIH 3T3 fibroblast and RIE-1 epithelial cells (Q42795734)

7 November 2017

Ras inactivation of the retinoblastoma pathway by distinct mechanisms in NIH 3T3 fibroblast and RIE-1 epithelial cells (English)

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7 November 2017

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Pruitt K

1

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7 November 2017

Pestell RG

series ordinal

2

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7 November 2017

Der CJ

series ordinal

3

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7 November 2017

language of work or name

English

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publication date

1 December 2000

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Journal of Biological Chemistry

7 November 2017

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7 November 2017

275

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7 November 2017

52

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7 November 2017

40916-40924

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Understanding Ras: 'it ain't over 'til it's over'.

7 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Mechanisms and consequences of activation of protein kinase B/Akt

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

ras-transformed cells: altered levels of phosphatidylinositol-4,5-bisphosphate and catabolites

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Evidence for a Ras/Ral signaling cascade

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Ras caught in another affair: the exchange factors for Ral.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Multiple Ras functions can contribute to mammalian cell transformation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Cell cycle: routine role for Ras.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Cell cycle targets of Ras/Raf signalling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

How do small GTPase signal transduction pathways regulate cell cycle entry?

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Ras transformation results in an elevated level of cyclin D1 and acceleration of G1 progression in NIH 3T3 cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Induction of cell proliferation in quiescent NIH 3T3 cells by oncogenic c-Raf-1.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Multiple ras effector pathways contribute to G(1) cell cycle progression

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Cooperating oncogenes converge to regulate cyclin/cdk complexes.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Signals from Ras and Rho GTPases interact to regulate expression of p21Waf1/Cip1.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

The absence of p21Cip1/WAF1 alters keratinocyte growth and differentiation and promotes ras-tumor progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006682200

Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006682200

Ras activity late in G1 phase required for p27kip1 downregulation, passage through the restriction point, and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006682200

An analysis of Mek1 signaling in cell proliferation and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006682200

Ras induces anchorage-independent growth by subverting multiple adhesion-regulated cell cycle events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006682200

Ras signals to the cell cycle machinery via multiple pathways to induce anchorage-independent growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006682200

Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006682200

Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

rasH mutants deficient in GTP binding

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

p21ras is modified by a farnesyl isoprenoid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006682200

ras-induced neuronal differentiation of PC12 cells: possible involvement of fos and jun

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006682200

Biological assays for Ras transformation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Multiple DNA elements are required for the growth regulation of the mouse E2F1 promoter

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Assay for activity of mammalian cyclin D-dependent kinases CDK4 and CDK6.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006682200

Ras, but not Src, transformation of RIE-1 epithelial cells is dependent on activation of the mitogen-activated protein kinase cascade.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006682200

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006682200

Lack of relationship between CDK activity and G1 cyclin expression in breast cancer cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

New functional activities for the p21 family of CDK inhibitors

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M006682200

The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006682200

RhoA stimulates p27(Kip) degradation through its regulation of cyclin E/CDK2 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006682200

Ras-stimulated extracellular signal-related kinase 1 and RhoA activities coordinate platelet-derived growth factor-induced G1 progression through the independent regulation of cyclin D1 and p27

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M006682200

21 January 2018

Identifiers

DOI

10.1074/JBC.M006682200

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7 November 2017

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