Geldanamycin induces ErbB-2 degradation by proteolytic fragmentation (Q42800575)

7 November 2017

Geldanamycin induces ErbB-2 degradation by proteolytic fragmentation (English)

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7 November 2017

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Tikhomirov O

1

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PubMed ID

10862618

7 November 2017

Carpenter G

series ordinal

2

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PubMed ID

10862618

7 November 2017

language of work or name

English

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publication date

1 August 2000

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Journal of Biological Chemistry

7 November 2017

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7 November 2017

275

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7 November 2017

34

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7 November 2017

26625-26631

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Specificity within the EGF family/ErbB receptor family signaling network

7 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.M003114200

The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand-receptor interactions

21 January 2018

1 reference

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Interaction between the adhesion receptor, CD44, and the oncogene product, p185HER2, promotes human ovarian tumor cell activation

21 January 2018

1 reference

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The p185(neu)-containing glycoprotein complex of a microfilament-associated signal transduction particle. Purification, reconstitution, and molecular associations with p58(gag) and actin

21 January 2018

1 reference

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Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells

21 January 2018

1 reference

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Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.

21 January 2018

1 reference

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erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells

21 January 2018

1 reference

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Increased expression of the putative growth factor receptor p185HER2 causes transformation and tumorigenesis of NIH 3T3 cells

21 January 2018

1 reference

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Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

21 January 2018

1 reference

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Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

21 January 2018

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Herbimycin, a new antibiotic produced by a strain of Streptomyces

21 January 2018

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The hsp90-based chaperone system: involvement in signal transduction from a variety of hormone and growth factor receptors

21 January 2018

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The role of the hsp90-based chaperone system in signal transduction by nuclear receptors and receptors signaling via MAP kinase

21 January 2018

1 reference

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p185erbB2 binds to GRP94 in vivo. Dissociation of the p185erbB2/GRP94 heterocomplex by benzoquinone ansamycins precedes depletion of p185erbB2.

21 January 2018

1 reference

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Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin

21 January 2018

1 reference

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21 January 2018

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Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

21 January 2018

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All ErbB receptors other than the epidermal growth factor receptor are endocytosis impaired

21 January 2018

1 reference

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Oncogenic activation of p185neu stimulates tyrosine phosphorylation in vivo

21 January 2018

1 reference

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21 January 2018

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The HER-2/neu receptor tyrosine kinase gene encodes a secreted autoinhibitor

21 January 2018

1 reference

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p50(cdc37) binds directly to the catalytic domain of Raf as well as to a site on hsp90 that is topologically adjacent to the tetratricopeptide repeat binding site

21 January 2018

1 reference

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p50(cdc37) acting in concert with Hsp90 is required for Raf-1 function

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M003114200

1 reference

7 November 2017

1 reference

PubMed ID

10862618