Selection of a histidine-containing inhibitor of gelatinases through deconvolution of combinatorial tetrapeptide libraries (Q42803020)

7 November 2017

Selection of a histidine-containing inhibitor of gelatinases through deconvolution of combinatorial tetrapeptide libraries (English)

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7 November 2017

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G Ferry

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7 November 2017

J A Boutin

2

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7 November 2017

G Atassi

3

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7 November 2017

J L Fauchère

4

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7 November 2017

G C Tucker

5

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7 November 2017

1 January 1997

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7 November 2017

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2

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7 November 2017

3

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7 November 2017

135-146

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https://scigraph.springernature.com/pub.10.1007/bf01682201

7 November 2017

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Matrix metalloproteinases cleave at two distinct sites on human cartilage link protein

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Rapid identification of highly active and selective substrates for stromelysin and matrilysin using bacteriophage peptide display libraries

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Overexpression of metalloproteinase inhibitor in B16F10 cells does not affect extravasation but reduces tumor growth.

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A new type of synthetic peptide library for identifying ligand-binding activity

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Protein design: novel metal-binding sites

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One-bead-one-structure combinatorial libraries

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12 December 2020

Applications of combinatorial technologies to drug discovery. 1. Background and peptide combinatorial libraries

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12 December 2020

Inhibition of tumor cell invasion by a highly conserved peptide sequence from the matrix metalloproteinase enzyme prosegment

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Melanoma-mediated dissolution of extracellular matrix: contribution of urokinase-dependent and metalloproteinase-dependent proteolytic pathways.

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Novel zinc chelators with dual activity in the inhibition of the kappa B site-binding proteins HIV-EP1 and NF-kappa B.

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Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells

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General method for rapid synthesis of multicomponent peptide mixtures

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Galectin-3 is a novel substrate for human matrix metalloproteinases-2 and -9.

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Messenger RNA for two type IV collagenases is located in stromal cells in human colon cancer.

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A synthetic matrix metalloproteinase inhibitor decreases tumor burden and prolongs survival of mice bearing human ovarian carcinoma xenografts

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Identification of substrate-analog trypsin inhibitors through the screening of synthetic peptide combinatorial libraries

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Tumor Cell Invasion Inhibited by TIMP-2

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Inhibition of human type IV collagenase by a highly conserved peptide sequence derived from its prosegment

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Identification of highest-affinity ligands by affinity selection from equimolar peptide mixtures generated by robotic synthesis

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Combinatorial peptide libraries: robotic synthesis and analysis by nuclear magnetic resonance, mass spectrometry, tandem mass spectrometry, and high-performance capillary electrophoresis techniques.

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Potent peptide inhibitors of stromelysin based on the prodomain region of matrix metalloproteinases

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Synthetic library techniques: subjective (biased and generic) thoughts and views

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Suppression of the tumorigenic and metastatic abilities of murine B16-F10 melanoma cells in vivo by the overexpression of the tissue inhibitor of the metalloproteinases-1

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Matrix metalloproteinases and their inhibitors in connective tissue remodeling

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Characterization of Extracellular Alkaline Proteases and Collagenase Induction in Vibrio alginolyticus

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Secretion of type IV collagenolytic protease and metastatic phenotype: induction by transfection with c-Ha-ras but not c-Ha-ras plus Ad2-E1a

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The rapid identification of HIV protease inhibitors through the synthesis and screening of defined peptide mixtures

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Zinc coordination, function, and structure of zinc enzymes and other proteins

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Angiogenesis inhibition: a review

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Stromal involvement in malignant growth

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Purification of human collagenases with a hydroxamic acid affinity column

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Metal binding peptide inhibitors of vertebrate collagenase

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Effect of tissue inhibitor of the matrix metalloproteinases-2 expression on the growth and spontaneous metastasis of a human melanoma cell line.

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Site-directed mutations that alter the inhibitory activity of the tissue inhibitor of metalloproteinases-1: importance of the N-terminal region between cysteine 3 and cysteine 13

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Mutational analysis of residues in and around the active site of human fibroblast-type collagenase

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Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substrates

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The matrix-degrading metalloproteinases

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Inhibition by human recombinant tissue inhibitor of metalloproteinases of human amnion invasion and lung colonization by murine B16-F10 melanoma cells

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Cyclic peptide template combinatorial libraries: synthesis and identification of chymotrypsin inhibitors

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Protease inhibitors: role and potential therapeutic use in human cancer

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Quantitative zymography: detection of picogram quantities of gelatinases

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12 December 2020

A high throughput fluorogenic substrate for interstitial collagenase (MMP-1) and gelatinase (MMP-9)

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12 December 2020

The broad utility of soluble peptide libraries for drug discovery

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12 December 2020

Type IV collagenases in tumor invasion and metastasis

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12 December 2020

Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery

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12 December 2020

Functional domains of human TIMP-1 (tissue inhibitor of metalloproteinases)

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12 December 2020

Extracellular matrix 6: role of matrix metalloproteinases in tumor invasion and metastasis.

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12 December 2020

Applications of combinatorial technologies to drug discovery. 2. Combinatorial organic synthesis, library screening strategies, and future directions

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12 December 2020

Identifiers

DOI

10.1007/BF01682201

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7 November 2017

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