Mechanism of inhibition of P-glycoprotein-mediated drug transport by protein kinase C blockers (Q42808368)

7 November 2017

title

Mechanism of inhibition of P-glycoprotein-mediated drug transport by protein kinase C blockers (English)

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7 November 2017

A F Castro

1

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7 November 2017

J K Horton

series ordinal

2

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7 November 2017

C G Vanoye

series ordinal

3

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7 November 2017

G A Altenberg

series ordinal

4

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7 November 2017

language of work or name

English

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publication date

1 December 1999

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7 November 2017

published in

Biochemical Pharmacology

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7 November 2017

volume

58

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7 November 2017

issue

11

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7 November 2017

page(s)

1723-1733

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Biochemistry of multidrug resistance mediated by the multidrug transporter

7 November 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0006-2952%2899%2900288-9

The P-glycoprotein efflux pump: how does it transport drugs?

7 January 2021

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Effects of phosphorylation of P-glycoprotein on multidrug resistance

7 January 2021

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Differential modulation of P-glycoprotein transport by protein kinase inhibition

7 January 2021

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Staurosporine, a potent inhibitor of C-kinase, enhances drug accumulation in multidrug-resistant cells.

7 January 2021

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Modulation of P-glycoprotein phosphorylation and drug transport by sodium butyrate

7 January 2021

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Comparison of staurosporine and four analogues: their effects on growth, rhodamine 123 retention and binding to P-glycoprotein in multidrug-resistant MCF-7/Adr cells

7 January 2021

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Circumvention of P-glycoprotein-mediated multiple drug resistance by phosphorylation modulators is independent of protein kinases

7 January 2021

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Staurosporine derivatives reverse multidrug resistance without correlation with their protein kinase inhibitory activities.

7 January 2021

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Changes in intra- or extracellular pH do not mediate P-glycoprotein-dependent multidrug resistance.

7 January 2021

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Inhibition of drug transport by genistein in multidrug-resistant cells expressing P-glycoprotein

7 January 2021

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P-glycoprotein is not a swelling-activated Cl- channel; possible role as a Cl- channel regulator.

7 January 2021

1 reference

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P-glycoprotein-associated chloride currents revealed by specific block by an anti-P-glycoprotein antibody

7 January 2021

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Unidirectional fluxes of rhodamine 123 in multidrug-resistant cells: evidence against direct drug extrusion from the plasma membrane

7 January 2021

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Characterization of a novel bisacridone and comparison with PSC 833 as a potent and poorly reversible modulator of P-glycoprotein.

7 January 2021

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A new method for a quantitative assessment of P-glycoprotein-related multidrug resistance in tumour cells

7 January 2021

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Kinetic analysis of calcein and calcein-acetoxymethylester efflux mediated by the multidrug resistance protein and P-glycoprotein

7 January 2021

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Preparing nuclei from cells in monolayer cultures suitable for counting and for following synchronized cells through the cell cycle

7 January 2021

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Phosphorylation by protein kinase C and cyclic AMP-dependent protein kinase of synthetic peptides derived from the linker region of human P-glycoprotein

7 January 2021

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Phosphorylation site mutations in the human multidrug transporter modulate its drug-stimulated ATPase activity

7 January 2021

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An N-myristoylated protein kinase C-alpha pseudosubstrate peptide that functions as a multidrug resistance reversal agent in human breast cancer cells is not a P-glycoprotein substrate

7 January 2021

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Partial Inhibition of Multidrug Resistance by Safingol Is Independent of Modulation of P-glycoprotein Substrate Activities and Correlated with Inhibition of Protein Kinase C

7 January 2021

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Protein kinase-independent inhibition of muscarinic K+ channels by staurosporine

7 January 2021

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Characterization of phosphorylation-defective mutants of human P-glycoprotein expressed in mammalian cells

7 January 2021

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Protein kinase C-mediated phosphorylation does not regulate drug transport by the human multidrug resistance P-glycoprotein

7 January 2021

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Effects of sphingosine stereoisomers on P-glycoprotein phosphorylation and vinblastine accumulation in multidrug-resistant MCF-7 cells.

7 January 2021

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Potent induction of human colon cancer cell uptake of chemotherapeutic drugs by N-myristoylated protein kinase C-alpha (PKC-alpha) pseudosubstrate peptides through a P-glycoprotein-independent mechanism

7 January 2021

1 reference

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Protein kinase C phosphorylation disengages human and mouse-1a P-glycoproteins from influencing the rate of activation of swelling-activated chloride currents

7 January 2021

1 reference

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Phosphorylation of P-glycoprotein by PKA and PKC modulates swelling-activated Cl- currents.

7 January 2021

1 reference

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10.1016/S0006-2952(99)00288-9

7 January 2021

Identifiers

DOI

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7 November 2017

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