Mutant Met-mediated transformation is ligand-dependent and can be inhibited by HGF antagonists (Q42810535)

7 November 2017

title

Mutant Met-mediated transformation is ligand-dependent and can be inhibited by HGF antagonists (English)

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7 November 2017

8

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7 November 2017

Bardelli A

7

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author name string

Michieli P

1

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7 November 2017

Basilico C

2

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7 November 2017

Pennacchietti S

3

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7 November 2017

Maffè A

4

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7 November 2017

Tamagnone L

5

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7 November 2017

Giordano S

6

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7 November 2017

language of work or name

English

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publication date

1 September 1999

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7 November 2017

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7 November 2017

volume

18

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7 November 2017

issue

37

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7 November 2017

page(s)

5221-5231

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A natural hepatocyte growth factor/scatter factor autocrine loop in myoblast cells and the effect of the constitutive Met kinase activation on myogenic differentiation

7 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Uncoupling signal transducers from oncogenic MET mutants abrogates cell transformation and inhibits invasive growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

"Invasive-growth" signaling by the Met/HGF receptor: the hereditary renal carcinoma connection.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Essential role for the c-met receptor in the migration of myogenic precursor cells into the limb bud

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Full activation of MEN2B mutant RET by an additional MEN2A mutation or by ligand GDNF stimulation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Glial cell line-derived neurotrophic factor differentially stimulates ret mutants associated with the multiple endocrine neoplasia type 2 syndromes and Hirschsprung's disease.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Identification of a Competitive HGF Antagonist Encoded by an Alternative Transcript

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Insights into the structure of hepatocyte growth factor/scatter factor (HGF/SF) and implications for receptor activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Targeting of the SF/HGF receptor to the basolateral domain of polarized epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Inhibition of tumor growth and invasion by a four-kringle antagonist (HGF/NK4) for hepatocyte growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

HGF/NK4 is a specific antagonist for pleiotrophic actions of hepatocyte growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Hepatocyte growth factor/scatter factor is an axonal chemoattractant and a neurotrophic factor for spinal motor neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Duplication and overexpression of the mutant allele of the MET proto-oncogene in multiple hereditary papillary renal cell tumours

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Hepatocyte growth factor induces proliferation and differentiation of multipotent and erythroid hemopoietic progenitors.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

A point mutation in the MET oncogene abrogates metastasis without affecting transformation.

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Scatter factor induces blood vessel formation in vivo

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

A mutation in the RET proto-oncogene associated with multiple endocrine neoplasia type 2B and sporadic medullary thyroid carcinoma

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

The mutationally activated Met receptor mediates motility and metastasis

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Activating mutations for the met tyrosine kinase receptor in human cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

ONCOGENESIS: Landscaping the Cancer Terrain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Somatic c-KIT activating mutation in urticaria pigmentosa and aggressive mastocytosis: establishment of clonality in a human mast cell neoplasm

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Uncoupling of Grb2 from the Met receptor in vivo reveals complex roles in muscle development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Role of aspartic acid 814 in the function and expression of c-kit receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Biological Activation of pro-HGF (Hepatocyte Growth Factor) by Urokinase Is Controlled by a Stoichiometric Reaction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Familial gastrointestinal stromal tumours with germline mutation of the KIT gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Hepatocyte growth factor/scatter factor effects on epithelia. Regulation of intercellular junctions in transformed and nontransformed cell lines, basolateral polarization of c-met receptor in transformed and natural intestinal epithelia, and inducti

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Hepatocyte growth factor/scatter factor and its receptor, the c-met proto-oncogene product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Scatter factor/hepatocyte growth factor is essential for liver development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Heparin induces dimerization and confers proliferative activity onto the hepatocyte growth factor antagonists NK1 and NK2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Scatter factor is a fibroblast-derived modulator of epithelial cell mobility

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Control of invasive growth by hepatocyte growth factor (HGF) and related scatter factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Evidence for the identity of human scatter factor and human hepatocyte growth factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephros

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Sequential requirement of hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Trisomy 7-harbouring non-random duplication of the mutant MET allele in hereditary papillary renal carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1202899

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1202899

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Dimensions Publication ID

7 November 2017

1028275437

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