Transmitochondrial mice carrying resistance to chloramphenicol on mitochondrial DNA: developing the first mouse model of mitochondrial DNA disease. (Q42812725)

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scientific article published on August 1999

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English	Transmitochondrial mice carrying resistance to chloramphenicol on mitochondrial DNA: developing the first mouse model of mitochondrial DNA disease.	scientific article published on August 1999

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scholarly article

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10 December 2019

Transmitochondrial mice carrying resistance to chloramphenicol on mitochondrial DNA: developing the first mouse model of mitochondrial DNA disease (English)

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10 December 2019

mitochondrial DNA

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inferred from title

chloramphenicol

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3

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10 December 2019

author name string

Marchington DR

1

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10 December 2019

Barlow D

2

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10 December 2019

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publication date

1 August 1999

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10 December 2019

Nature Medicine

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10 December 2019

5

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10 December 2019

957-960

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10 December 2019

8

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10 December 2019

https://scigraph.springernature.com/pub.10.1038/11403

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A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator

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Random genetic drift in the female germline explains the rapid segregation of mammalian mitochondrial DNA.

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Mitochondria transfer into mouse ova by microinjection

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Altered ribosomal RNA genes in mitochondria from mammalian cells with chloramphenicol resistance

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Mitochondrial chloramphenicol-resistant mutants can have deficiencies in energy metabolism

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Nondroplet ultrastructural demonstration of cytochrome oxidase activity with a polymerizing osmiophilic reagent, diaminobenzidine (DAB).

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Evidence from mtDNA sequences that common laboratory strains of inbred mice are descended from a single female

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Mitochondrial ribosomal RNA mutation associated with both antibiotic-induced and non-syndromic deafness

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Mitochondrial ribosomal RNA gene mutation in a patient with sporadic aminoglycoside ototoxicity.

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Biochemical evidence for nuclear gene involvement in phenotype of non-syndromic deafness associated with mitochondrial 12S rRNA mutation

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Defects in mitochondrial protein synthesis and respiratory chain activity segregate with the tRNA(Leu(UUR)) mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes

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Identifiers

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Europe PubMed Central

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10 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10426324%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

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