Overexpression of Runx2 and MKP-1 stimulates transdifferentiation of 3T3-L1 preadipocytes into bone-forming osteoblasts in vitro (Q42815602)

7 November 2017

Overexpression of Runx2 and MKP-1 stimulates transdifferentiation of 3T3-L1 preadipocytes into bone-forming osteoblasts in vitro (English)

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7 November 2017

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Tomihisa Takahashi

1

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PubMed ID

21258786

7 November 2017

language of work or name

English

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publication date

23 January 2011

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Calcified Tissue International

7 November 2017

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7 November 2017

88

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7 November 2017

4

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7 November 2017

336-347

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https://scigraph.springernature.com/pub.10.1007/s00223-011-9461-9

7 November 2017

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Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts

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Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene

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Transcriptional regulation of osteopontin gene in vivo by PEBP2alphaA/CBFA1 and ETS1 in the skeletal tissues

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Cloning of a 2.5 kb murine bone sialoprotein promoter fragment and functional analysis of putative Osf2 binding sites

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Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation

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Cell-type-dependent up-regulation of in vitro mineralization after overexpression of the osteoblast-specific transcription factor Runx2/Cbfal

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Exogenous Runx2 expression enhances in vitro osteoblastic differentiation and mineralization in primary bone marrow stromal cells

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Glucocorticoid-induced osteogenesis is negatively regulated by Runx2/Cbfa1 serine phosphorylation.

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Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development

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Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures

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High bone resorption in adult aging transgenic mice overexpressing cbfa1/runx2 in cells of the osteoblastic lineage

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Structural organization of mouse peroxisome proliferator-activated receptor gamma (mPPAR gamma) gene: alternative promoter use and different splicing yield two mPPAR gamma isoforms

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The DNA binding domain of the rat liver nuclear protein C/EBP is bipartite

21 January 2018

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Cascade regulation of terminal adipocyte differentiation by three members of the C/EBP family of leucine zipper proteins

21 January 2018

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Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells

21 January 2018

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CCAAT/enhancer binding protein gene promoter: binding of nuclear factors during differentiation of 3T3-L1 preadipocytes

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CAAT/enhancer binding proteins directly modulate transcription from the peroxisome proliferator-activated receptor gamma 2 promoter

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CCAAT/enhancer binding protein alpha is sufficient to initiate the 3T3-L1 adipocyte differentiation program

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Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor

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Subcutaneous adipocytes can differentiate into bone-forming cells in vitro and in vivo

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Runx2 overexpression enhances osteoblastic differentiation and mineralization in adipose--derived stem cells in vitro and in vivo

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Mature adipocyte-derived dedifferentiated fat cells can trans-differentiate into osteoblasts in vitro and in vivo only by all-trans retinoic acid

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An established pre-adipose cell line and its differentiation in culture.

21 January 2018

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Formation of normally differentiated subcutaneous fat pads by an established preadipose cell line

21 January 2018

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Dexamethasone promotes DMP1 mRNA expression by inhibiting negative regulation of Runx2 in multipotential mesenchymal progenitor, ROB-C26.

21 January 2018

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Cbfa1 isoforms exert functional differences in osteoblast differentiation

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IL-1alpha affects mineralized nodule formation by rat osteoblasts

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Netoglitazone is a PPAR-gamma ligand with selective effects on bone and fat.

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Ectopic overexpression of adipogenic transcription factors induces transdifferentiation of MC3T3-E1 osteoblasts

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The role of C/EBP genes in adipocyte differentiation.

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TAZ, a transcriptional modulator of mesenchymal stem cell differentiation

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Core-binding factor beta interacts with Runx2 and is required for skeletal development

21 January 2018

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The core-binding factor beta subunit is required for bone formation and hematopoietic maturation

21 January 2018

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Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12.

21 January 2018

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A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia

21 January 2018

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Stat1 functions as a cytoplasmic attenuator of Runx2 in the transcriptional program of osteoblast differentiation

21 January 2018

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Dominance of SOX9 function over RUNX2 during skeletogenesis

21 January 2018

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Characterization of a novel KRAB/C2H2 zinc finger transcription factor involved in bone development.

21 January 2018

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Nrf2 negatively regulates osteoblast differentiation via interfering with Runx2-dependent transcriptional activation

21 January 2018

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SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation

21 January 2018

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Nuclear phosphatases and the proteasome in suppression of STAT1 activity in hepatocytes

21 January 2018

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Bone morphogenetic protein and retinoic acid signaling cooperate to induce osteoblast differentiation of preadipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00223-011-9461-9

10.1007/S00223-011-9461-9

21 January 2018

Identifiers

DOI

1 reference

PubMed ID

21258786

Dimensions Publication ID

7 November 2017

0 references

1 reference

PubMed ID

21258786