Calmodulin inhibitor W13 induces sustained activation of ERK2 and expression of p21(cip1). (Q42827172)

8 November 2017

Calmodulin inhibitor W13 induces sustained activation of ERK2 and expression of p21(cip1). (English)

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8 November 2017

2

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8 November 2017

4

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8 November 2017

M Bosch

1

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PubMed ID

9705360

8 November 2017

O Bachs

series ordinal

3

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PubMed ID

9705360

8 November 2017

language of work or name

English

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publication date

1 August 1998

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Journal of Biological Chemistry

8 November 2017

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8 November 2017

273

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8 November 2017

34

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8 November 2017

22145-22150

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Mitogen-activated protein kinase pathways

8 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

The pathways connecting G protein-coupled receptors to the nucleus through divergent mitogen-activated protein kinase cascades

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

cPLA2 is phosphorylated and activated by MAP kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Epidermal growth factor (EGF) receptor T669 peptide kinase from 3T3-L1 cells is an EGF-stimulated "MAP" kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Phosphorylation of transcription factor p62TCF by MAP kinase stimulates ternary complex formation at c-fos promoter

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Transcriptional regulation by extracellular signals: mechanisms and specificity

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Activation of the MAP kinase pathway by the protein kinase raf

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Activation of Raf as a result of recruitment to the plasma membrane

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Physical association with ras enhances activation of membrane-bound raf (RafCAAX).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Regulation of p21ras by GTPase activating proteins and guanine nucleotide exchange proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

High-intensity Raf signal causes cell cycle arrest mediated by p21Cip1.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Raf-induced proliferation or cell cycle arrest is determined by the level of Raf activity with arrest mediated by p21Cip1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Isolation and characterization of a novel dual specific phosphatase, HVH2, which selectively dephosphorylates the mitogen-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Control of MAP kinase activation by the mitogen-induced threonine/tyrosine phosphatase PAC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Regulation of mitogen-activated protein kinase phosphatase-1 expression by extracellular signal-related kinase-dependent and Ca2+-dependent signal pathways in Rat-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Regulation of epidermal growth factor receptor signaling by phosphorylation of the ras exchange factor hSOS1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

The multifunctional Ca2+/calmodulin-dependent protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Calmodulin regulates DNA polymerase alpha activity during proliferative activation of NRK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

New nuclear functions for calmodulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Activation of Raf-1 by Ras in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Minimal Ras-binding domain of Raf1 can be used as an activation-specific probe for Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Sustained activation of extracellular-signal-regulated kinase 1 (ERK1) is required for the continued expression of cyclin D1 in G1 phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

New functional activities for the p21 family of CDK inhibitors

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Calcium inhibits epidermal growth factor-induced activation of p21ras in human primary keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

The human epidermal growth factor receptor contains a juxtamembrane calmodulin-binding site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Phosphorylation-dependent activation of the Ras-GRF/CDC25Mm exchange factor by muscarinic receptors and G-protein beta gamma subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

The N-terminal moiety of CDC25(Mm), a GDP/GTP exchange factor of Ras proteins, controls the activity of the catalytic domain. Modulation by calmodulin and calpain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Calmodulin modulates the interaction between IQGAP1 and Cdc42. Identification of IQGAP1 by nanoelectrospray tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Calmodulin-dependent protein kinase II mediates inactivation of MPF and CSF upon fertilization of Xenopus eggs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Overexpression of the myristoylated alanine-rich C-kinase substrate in Rat1 cells increases sensitivity to calmodulin antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Changes in calmodulin and its mRNA accompany reentry of quiescent (G0) cells into the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Calmodulin stimulates DNA synthesis by rat liver cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Calmodulin and the cell cycle: involvement in regulation of cell-cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Low concentrations of trifluoperazine arrest the cell division cycle of Saccharomyces cerevisiae at two specific stages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Identification of an essential signaling cascade for mitogen-activated protein kinase activation by angiotensin II in cultured rat vascular smooth muscle cells. Possible requirement of Gq-mediated p21ras activation coupled to a Ca2+/calmodulin-sensi

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Calcium/calmodulin-dependent protein kinase IIalpha mediates activation of mitogen-activated protein kinase and cytosolic phospholipase A2 in norepinephrine-induced arachidonic acid release in rabbit aortic smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Addition of calmodulin antagonists to NRK cells during G1 inhibits proliferating cell nuclear antigen expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

Calmodulin is involved in the induction of DNA polymerases alpha and delta activities in normal rat kidney cells activated to proliferate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.273.34.22145

21 January 2018

Identifiers

DOI

10.1074/JBC.273.34.22145

1 reference

8 November 2017

1 reference

PubMed ID

9705360