A switch from p130Cas/Crk to Gab1/Crk signaling correlates with anchorage independent growth and JNK activation in cells transformed by the Met receptor oncoprotein (Q42832806)

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scientific article published on December 2000

Language	Label	Description	Also known as
English	A switch from p130Cas/Crk to Gab1/Crk signaling correlates with anchorage independent growth and JNK activation in cells transformed by the Met receptor oncoprotein	scientific article published on December 2000

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scholarly article

1 reference

Europe PubMed Central

8 November 2017

A switch from p130Cas/Crk to Gab1/Crk signaling correlates with anchorage independent growth and JNK activation in cells transformed by the Met receptor oncoprotein (English)

1 reference

Europe PubMed Central

8 November 2017

author name string

Lamorte L

1

1 reference

Europe PubMed Central

8 November 2017

Kamikura DM

2

1 reference

Europe PubMed Central

8 November 2017

Park M

3

1 reference

Europe PubMed Central

8 November 2017

language of work or name

0 references

publication date

1 December 2000

1 reference

Europe PubMed Central

8 November 2017

1 reference

Europe PubMed Central

8 November 2017

19

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Europe PubMed Central

8 November 2017

52

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Europe PubMed Central

8 November 2017

5973-5981

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Europe PubMed Central

8 November 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1203977

0 references

Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Anchorage-dependent cell cycle progression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

The adaptor protein Crk connects multiple cellular stimuli to the JNK signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Interaction with the phosphotyrosine binding domain/phosphotyrosine interacting domain of SHC is required for the transforming activity of the FLT4/VEGFR3 receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Efficient cellular transformation by the Met oncoprotein requires a functional Grb2 binding site and correlates with phosphorylation of the Grb2-associated proteins, Cbl and Gab1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Met-induced JNK activation is mediated by the adapter protein Crk and correlates with the Gab1 - Crk signaling complex formation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Organization and regulation of mitogen-activated protein kinase signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

A point mutation in the MET oncogene abrogates metastasis without affecting transformation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Cloning of p97/Gab2, the major SHP2-binding protein in hematopoietic cells, reveals a novel pathway for cytokine-induced gene activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

The activated insulin-like growth factor I receptor induces depolarization in breast epithelial cells characterized by actin filament disassembly and tyrosine dephosphorylation of FAK, Cas, and paxillin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Signaling through focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130Cas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Enhanced transformation by a plasma membrane-associated met oncoprotein: activation of a phosphoinositide 3'-kinase-dependent autocrine loop involving hyaluronic acid and CD44.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Identification of tyrosine 489 in the carboxy terminus of the Tpr-Met oncoprotein as a major site of autophosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Emerging components of the Crk oncogene product: the first identified adaptor protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Integrin-mediated activation of focal adhesion kinase is required for signaling to Jun NH2-terminal kinase and progression through the G1 phase of the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Mechanism of met oncogene activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Phosphorylation of tyrosine residues 31 and 118 on paxillin regulates cell migration through an association with CRK in NBT-II cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

DOS, a novel pleckstrin homology domain-containing protein required for signal transduction between sevenless and Ras1 in Drosophila.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Dimerization mediated through a leucine zipper activates the oncogenic potential of the met receptor tyrosine kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Activation of the JNK pathway is essential for transformation by the Met oncogene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Integrin signalling and tyrosine phosphorylation: just the FAKs?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Bidirectional signaling between the cytoskeleton and integrins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Integrins, oncogenes, and anchorage independence.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Downstream of Crk adaptor signaling pathway: activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

The stress-activated protein kinase pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Introduction of p130cas signaling complex formation upon integrin-mediated cell adhesion: a role for Src family kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Tyrosine phosphorylation of p130Cas and cortactin accompanies integrin-mediated cell adhesion to extracellular matrix

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

21 January 2018

Protein tyrosine kinases and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

7 January 2021

based on heuristic

inferred from DOI database lookup

The Cbl protooncogene product: from an enigmatic oncogene to center stage of signal transduction.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203977

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1203977

1 reference

Europe PubMed Central

8 November 2017

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1 reference

Europe PubMed Central

8 November 2017

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