Antibodies to insulin receptor tyrosine kinase stimulate its activity towards exogenous substrates without inducing receptor autophosphorylation. (Q42836425)

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scientific article published on June 1989

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English	Antibodies to insulin receptor tyrosine kinase stimulate its activity towards exogenous substrates without inducing receptor autophosphorylation.	scientific article published on June 1989

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2764902%20AND%20SRC:MED&resulttype=core&format=json

4 October 2019

Antibodies to insulin receptor tyrosine kinase stimulate its activity towards exogenous substrates without inducing receptor autophosphorylation (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2764902%20AND%20SRC:MED&resulttype=core&format=json

4 October 2019

Nathalie Rochet

3

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4 October 2019

Robert Ballotti

4

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4 October 2019

author name string

V Baron

1

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4 October 2019

N Gautier

2

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4 October 2019

B Rossi

5

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4 October 2019

S Saint-Pierre

6

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4 October 2019

E Van Obberghen

7

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4 October 2019

J Dolais-Kitabgi

8

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4 October 2019

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publication date

1 June 1989

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4 October 2019

Biochemical Journal

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4 October 2019

260

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4 October 2019

3

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4 October 2019

749-756

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4 October 2019

Biochemical and morphological evidence that the insulin receptor is internalized with insulin in hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138740

27 May 2018

Synthetic tyrosine polymers as substrates and inhibitors of tyrosine-specific protein kinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138740

27 May 2018

Receptor-mediated phosphorylation of the hepatic insulin receptor: Evidence that the M r 95,000 receptor subunit is its own kinase

1 reference

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27 May 2018

Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells

1 reference

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27 May 2018

Insulin activates a tyrosine-specific protein kinase in extracts of 3T3-L1 adipocytes and human placenta.

1 reference

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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27 May 2018

Solid-phase peptide synthesis

1 reference

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27 May 2018

Acute insulin action requires insulin receptor kinase activity: introduction of an inhibitory monoclonal antibody into mammalian cells blocks the rapid effects of insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138740

27 May 2018

A mutant insulin receptor with defective tyrosine kinase displays no biologic activity and does not undergo endocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138740

27 May 2018

A thousand and one protein kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138740

27 May 2018

Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138740

27 May 2018

Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors

1 reference

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27 May 2018

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138740

27 May 2018

Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138740

27 May 2018

A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138740

27 May 2018

The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138740

27 May 2018

An antipeptide antibody that specifically inhibits insulin receptor autophosphorylation and protein kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138740

27 May 2018

Protein thiolation and reversible protein-protein conjugation. N-Succinimidyl 3-(2-pyridyldithio)propionate, a new heterobifunctional reagent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138740

27 May 2018

Insulin receptor tyrosine kinase is defective in skeletal muscle of insulin-resistant obese mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138740

27 May 2018

Defect in Phosphorylation of Insulin Receptors in Cells from an Insulin-Resistant Patient with Normal Insulin Binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138740

16 August 2018

A cascade of tyrosine autophosphorylation in the beta-subunit activates the phosphotransferase of the insulin receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1138740

16 August 2018

Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system

1 reference

https://pubmed.ncbi.nlm.nih.gov/2764902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of the hepatic insulin receptor: stimulating effect of insulin on intact cells and in a cell-free system

1 reference

https://pubmed.ncbi.nlm.nih.gov/2764902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-stimulated tyrosine phosphorylation of the insulin receptor in detergent extracts of human placental membranes. Comparison to epidermal growth factor-stimulated phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2764902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphorylation of synthetic insulin receptor peptides by the insulin receptor kinase and evidence that the preferred sequence containing Tyr-1150 is phosphorylated in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/2764902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophosphorylation of the insulin receptor in vitro. Designation of phosphorylation sites and correlation with receptor kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2764902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2764902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiphosphotyrosine antibodies modulate insulin receptor kinase activity and insulin action

1 reference

https://pubmed.ncbi.nlm.nih.gov/2764902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of antireceptor antibodies in stimulating phosphorylation of the insulin receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/2764902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defect in insulin receptor phosphorylation in erythrocytes and fibroblasts associated with severe insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/2764902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antibodies to deduced sequences of the insulin receptor distinguish conserved and nonconserved regions in the IGF-I receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/2764902

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ2600749

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2764902%20AND%20SRC:MED&resulttype=core&format=json

4 October 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2764902%20AND%20SRC:MED&resulttype=core&format=json

4 October 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:2764902%20AND%20SRC:MED&resulttype=core&format=json

4 October 2019

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