Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex (Q42912317)

11 November 2017

Terminal transport of lytic granules to the immune synapse is mediated by the kinesin-1/Slp3/Rab27a complex (English)

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11 November 2017

8

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Geneviève de Saint Basile

11 November 2017

series ordinal

7

object named as

Geneviève de Saint Basile

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Jérôme Garin

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5

object named as

Jérôme Garin

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Magali Court

series ordinal

4

object named as

Magali Court

1 reference

11 November 2017

3

Nadine T Nehme

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11 November 2017

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Alain Fischer

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11 November 2017

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Mathieu Kurowska

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11 November 2017

2

Nicolas Goudin

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11 November 2017

language of work or name

English

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publication date

3 February 2012

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119

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17

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3879-3889

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describes a project that uses

11 November 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3824283/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Kinesin 5B is necessary for delivery of membrane and receptors during FcγR-mediated phagocytosis

1 reference

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Kinesin I transports tetramerized Kv3 channels through the axon initial segment via direct binding

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Molecular mechanisms of centrosome and cytoskeleton anchorage at the nuclear envelope.

27 May 2018

1 reference

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Targeted inactivation of kinesin-1 in pancreatic β-cells in vivo leads to insulin secretory deficiency

27 May 2018

1 reference

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Molecular mechanisms of biogenesis and exocytosis of cytotoxic granules

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Rapid lytic granule convergence to the MTOC in natural killer cells is dependent on dynein but not cytolytic commitment

27 May 2018

1 reference

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The synapse and cytolytic machinery of cytotoxic T cells

27 May 2018

1 reference

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Kinetics of early T cell receptor signaling regulate the pathway of lytic granule delivery to the secretory domain

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

The strength of T cell receptor signal controls the polarization of cytotoxic machinery to the immunological synapse

27 May 2018

1 reference

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A newly identified isoform of Slp2a associates with Rab27a in cytotoxic T cells and participates to cytotoxic granule secretion

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Myosin IIA is required for cytolytic granule exocytosis in human NK cells

27 May 2018

1 reference

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Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4

27 May 2018

1 reference

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Perforin-mediated target-cell death and immune homeostasis

27 May 2018

1 reference

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Recruitment of dynein to the Jurkat immunological synapse

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Calsyntenin-1 docks vesicular cargo to kinesin-1

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

CRMP-2 is involved in kinesin-1-dependent transport of the Sra-1/WAVE1 complex and axon formation

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

The ciliary rootlet interacts with kinesin light chains and may provide a scaffold for kinesin-1 vesicular cargos

27 May 2018

1 reference

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Tubulin and CRMP-2 complex is transported via Kinesin-1

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Syntabulin is a microtubule-associated protein implicated in syntaxin transport in neurons

27 May 2018

1 reference

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Real-time visualization of the cytoskeleton and effector functions in T cells.

27 May 2018

1 reference

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The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain

27 May 2018

1 reference

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Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

A mutation in Rab27a causes the vesicle transport defects observed in ashen mice

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Mutations in RAB27A cause Griscelli syndrome associated with haemophagocytic syndrome

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Novel rabphilin-3-like protein associates with insulin-containing granules in pancreatic beta cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Chromosomal localization reveals three kinesin heavy chain genes in mouse

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Kinesin and dynein superfamily proteins and the mechanism of organelle transport

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Lytic granules from cytotoxic T cells exhibit kinesin-dependent motility on microtubules in vitro.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Suppression of kinesin expression in cultured hippocampal neurons using antisense oligonucleotides.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

KIF5B and KIF3A/KIF3B kinesins drive MT1-MMP surface exposure, CD44 shedding, and extracellular matrix degradation in primary macrophages

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Anterograde transport of TrkB in axons is mediated by direct interaction with Slp1 and Rab27.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Centrosome polarization delivers secretory granules to the immunological synapse.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Distinct Rab27A binding affinities of Slp2-a and Slac2-a/melanophilin: Hierarchy of Rab27A effectors.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Dynamic polarization of the microtubule cytoskeleton during CTL-mediated killing.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

The immunological synapse of CTL contains a secretory domain and membrane bridges.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Rab27a is required for regulated secretion in cytotoxic T lymphocytes

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

Kinesin-1 plays a role in transport of SNAP-25 to the plasma membrane

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3824283

10.1182/BLOOD-2011-09-382556

1 December 2018

Identifiers

DOI

1 reference

11 November 2017

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11 November 2017

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