Mutant N-RAS induces erythroid lineage dysplasia in human CD34+ cells (Q42947898)

11 November 2017

Mutant N-RAS induces erythroid lineage dysplasia in human CD34+ cells (English)

1 reference

11 November 2017

R L Darley

1

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11 November 2017

T G Hoy

2

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11 November 2017

P Baines

3

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11 November 2017

R A Padua

4

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11 November 2017

A K Burnett

5

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11 November 2017

language of work or name

English

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publication date

1 April 1997

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Journal of Experimental Medicine

11 November 2017

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11 November 2017

185

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11 November 2017

7

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11 November 2017

1337-1347

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Mutations of ras genes in human tumors (review).

11 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Involvement of the protein tyrosine phosphatase SHP-1 in Ras-mediated activation of the mitogen-activated protein kinase pathway.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Ras and myelodysplasia: lessons from the last decade.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Erythropoiesis in myelodysplastic syndrome: expression of receptors for erythropoietin and kit ligand

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Mutant ras promotes haemopoietic cell proliferation or differentiation in a cell-specific manner.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Induction of monocytic differentiation and tumorigenicity by v-Ha-ras in differentiation arrested hematopoietic cells.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Blast colony-forming cells in myelodysplastic syndrome: decreased potential to generate erythroid precursors.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Loss of erythropoietin responsiveness in erythroid progenitors due to expression of the Evi-1 myeloid-transforming gene

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Regulation of heme biosynthesis: distinct regulatory features in erythroid cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Apoptosis in erythroid progenitors deprived of erythropoietin occurs during the G1 and S phases of the cell cycle without growth arrest or stabilization of wild-type p53.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Activation of the mitogen-activated protein kinase pathway by the erythropoietin receptor.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Alterations in differentiation and behavior of monocytic phagocytes in transgenic mice that express dominant suppressors of ras signaling

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Ras target proteins in eukaryotic cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Interaction of the erythropoietin and stem-cell-factor receptors

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Fluorescence-activated cell analysis and sorting of viable mammalian cells based on beta-D-galactosidase activity after transduction of Escherichia coli lacZ

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Flow cytometric analysis of human bone marrow: I. Normal erythroid development.

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Reversible abrogation of IL-3 dependence by an inducible H-ras oncogene

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Erythropoietin retards DNA breakdown and prevents programmed death in erythroid progenitor cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Expression of the CD11/CD18, leukocyte adhesion molecule 1, and CD44 adhesion molecules during normal myeloid and erythroid differentiation in humans

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Molecular Genetic Aspects of Myelodysplastic Syndromes

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Three new cases of chromosome 3 rearrangement in bands q21 and q26 with abnormal thrombopoiesis bring further evidence to the existence of a 3q21q26 syndrome

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Activation of EVI1 gene expression in human acute myelogenous leukemias by translocations spanning 300-400 kilobases on chromosome band 3q26

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Erythropoietin induces p21ras activation and p120GAP tyrosine phosphorylation in human erythroleukemia cells

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Evi-1 expression in leukemic patients with rearrangements of the 3q25-q28 chromosomal region

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Growth factor-dependent inhibition of normal hematopoiesis by N-ras antisense oligodeoxynucleotides

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

The two-step liquid culture: a novel procedure for studying maturation of human normal and pathological erythroid precursors

27 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Genetic analysis is consistent with the hypothesis that NF1 limits myeloid cell growth through p21ras

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Proliferation and differentiation of myelodysplastic CD34+ cells: phenotypic subpopulations of marrow CD34+ cells.

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

Proliferative activity of bone marrow cells in primary dysmyelopoietic (preleukemic) syndromes

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

A pragmatic approach to the analysis of DNA histograms with a definable G1 peak

16 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2196261

A quantitative evaluation of erythropoiesis in myelodysplastic syndromes using multiparameter flow cytometry

16 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1084%2FJEM.185.7.1337

Clonal analysis of myelodysplastic syndromes: evidence of multipotent stem cell origin

21 January 2018

1 reference

12 December 2020

Expression of normal and mutant ras proteins in human acute leukemia

1 reference

12 December 2020

Aberrant expression of p21RAS but not p120GAP is a common feature of myelodysplasia

1 reference

12 December 2020

Abnormal erythroid progenitor cells in human preleukemia

1 reference

12 December 2020

Erythroid and granulocyte-macrophage colony formation in myelodysplastic syndromes

1 reference

12 December 2020

Apoptosis in bone marrow biopsy samples involving stromal and hematopoietic cells in 50 patients with myelodysplastic syndromes

1 reference

12 December 2020

Tumor necrosis factor (TNF)-alpha directly inhibits human erythropoiesis in vitro: role of p55 and p75 TNF receptors

1 reference

12 December 2020

The myelodysplastic syndrome: analysis of laboratory characteristics in relation to the FAB classification

1 reference

12 December 2020

Cell-cycle progression rates and sister chromatid exchange frequencies in the bone marrow of patients with myelodysplastic syndrome and acute myeloid leukemia

1 reference

12 December 2020

Stem cell factor retards differentiation of normal human erythroid progenitor cells while stimulating proliferation

1 reference

12 December 2020

Mechanistic options of erythropoietin-stimulated erythropoiesis

1 reference

12 December 2020

Haemopoietic colony-forming cells from peripheral blood stem cell harvests: cytokine requirements and lineage potential

1 reference

12 December 2020

A novel assay to measure loss of plasma membrane asymmetry during apoptosis of adherent cells in culture

1 reference

12 December 2020

Transforming growth factor beta (TGF-beta), a potent inhibitor of erythropoiesis: neutralizing TGF-beta antibodies show erythropoietin as a potent stimulator of murine burst-forming unit erythroid colony formation in the absence of a burst-promoting

1 reference

12 December 2020

Expression and extracellular release of transferrin receptors during peripheral erythroid progenitor cell differentiation in liquid culture

1 reference

12 December 2020

Hematologic abnormalities of the immunodeficient mouse mutant, viable motheaten (mev)

1 reference

12 December 2020

Human neutrophils lose their surface Fc gamma RIII and acquire Annexin V binding sites during apoptosis in vitro

1 reference

12 December 2020

Changes in cell surface antigen expressions during proliferation and differentiation of human erythroid progenitors

1 reference

12 December 2020

Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene

1 reference

12 December 2020

Retrovirus-mediated gene transduction into canine peripheral blood repopulating cells

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.185.7.1337

1 reference

11 November 2017

1 reference

11 November 2017

1 reference