The proinflammatory cytokines IL-1beta and TNF-alpha induce the expression of Synoviolin, an E3 ubiquitin ligase, in mouse synovial fibroblasts via the Erk1/2-ETS1 pathway (Q42962015)

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scientific article published on January 2006

Language	Label	Description	Also known as
English	The proinflammatory cytokines IL-1beta and TNF-alpha induce the expression of Synoviolin, an E3 ubiquitin ligase, in mouse synovial fibroblasts via the Erk1/2-ETS1 pathway	scientific article published on January 2006

Statements

scholarly article

1 reference

Europe PubMed Central

11 November 2017

The proinflammatory cytokines IL-1beta and TNF-alpha induce the expression of Synoviolin, an E3 ubiquitin ligase, in mouse synovial fibroblasts via the Erk1/2-ETS1 pathway (English)

1 reference

Europe PubMed Central

11 November 2017

author name string

Beixue Gao

1

1 reference

Europe PubMed Central

11 November 2017

Karen Calhoun

2

1 reference

Europe PubMed Central

11 November 2017

Deyu Fang

3

1 reference

Europe PubMed Central

11 November 2017

publication date

1 January 2006

1 reference

Europe PubMed Central

11 November 2017

Arthritis Research and Therapy

1 reference

Europe PubMed Central

11 November 2017

8

1 reference

Europe PubMed Central

11 November 2017

6

1 reference

Europe PubMed Central

11 November 2017

R172

1 reference

Europe PubMed Central

11 November 2017

https://scigraph.springernature.com/pub.10.1186/ar2081

0 references

Rheumatoid arthritis as a hyper-endoplasmic-reticulum-associated degradation disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Tumour necrosis factor activates the mitogen-activated protein kinases p38alpha and ERK in the synovial membrane in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Identification of a crucial site for synoviolin expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Matrix metalloproteinase-1 up-regulation by hepatocyte growth factor in human dermal fibroblasts via ERK signaling pathway involves Ets1 and Fli1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Essential role of synoviolin in embryogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Prostaglandin E2 enhances pancreatic cancer invasiveness through an Ets-1-dependent induction of matrix metalloproteinase-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Selective inhibition of NF-kappa B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo

1 reference

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26 May 2018

The role of interleukin-1 in bone resorption in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Regulation of c-Jun N-terminal kinase by MEKK-2 and mitogen-activated protein kinase kinase kinases in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Migration inhibitory factor mediates angiogenesis via mitogen-activated protein kinase and phosphatidylinositol kinase.

1 reference

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26 May 2018

Identification of the critical features of a small peptide inhibitor of JNK activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Selective in vivo inhibition of mitogen-activated protein kinase activation using cell-permeable peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Endoplasmic reticulum degradation requires lumen to cytosol signaling. Transmembrane control of Hrd1p by Hrd3p.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Jun N-terminal kinase in rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Signal transduction and transcription factors in rheumatic disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Pyrroles and other heterocycles as inhibitors of p38 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Pro- and anti-inflammatory cytokines in rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Tumor necrosis factor-α, interleukin 1, and phorbol myristate acetate are independent activators of NF-κB which differentially activate T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

26 May 2018

Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

16 August 2018

Expression of mitogen-activated protein kinase phosphatase 1, a negative regulator of the mitogen-activated protein kinases, in rheumatoid arthritis: up-regulation by interleukin-1beta and glucocorticoids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

16 August 2018

Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

16 August 2018

In vitro gene transfer to chondrocytes and synovial fibroblasts by adenoviral vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

16 August 2018

Accelerated nodulosis and vasculitis following etanercept therapy for rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

16 August 2018

Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

16 August 2018

The osteoprotegerin/receptor activator of nuclear factor kappaB/receptor activator of nuclear factor kappaB ligand system in cartilage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1794516

16 August 2018

Activation of the transcription factor nuclear factor-κB in human inflamed synovial tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/17105652

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ

1 reference

https://pubmed.ncbi.nlm.nih.gov/17105652

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of transcription factor Ets-1 in rheumatoid arthritis synovial membrane: regulation of expression and activation by interleukin-1 and tumor necrosis factor alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/17105652

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ETS-domain transcription factor family

1 reference

https://pubmed.ncbi.nlm.nih.gov/17105652

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of protein tyrosine kinase in IL-1 beta induced activation of mitogen-activated protein kinase in fibroblast-like synoviocytes of rheumatoid arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17105652

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of an Ets-1 dominant-negative mutant perturbs normal and tumor angiogenesis in a mouse ear model

1 reference

https://pubmed.ncbi.nlm.nih.gov/17105652

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-culture of synovial fibroblasts and differentiated U937 cells is sufficient for high interleukin-6 but not interleukin-1beta or tumour necrosis factor-alpha release

1 reference

https://pubmed.ncbi.nlm.nih.gov/17105652

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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Europe PubMed Central

11 November 2017

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Europe PubMed Central

11 November 2017

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Europe PubMed Central

11 November 2017

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