Interference with P-glycoprotein improves ivermectin activity against adult resistant nematodes in sheep (Q42982332)

12 November 2017

Interference with P-glycoprotein improves ivermectin activity against adult resistant nematodes in sheep (English)

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12 November 2017

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A Lifschitz

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12 November 2017

C Entrocasso

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12 November 2017

L Alvarez

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M Lloberas

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M Ballent

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G Manazza

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12 November 2017

G Virkel

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12 November 2017

B Borda

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12 November 2017

C Lanusse

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12 May 2010

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12 November 2017

Veterinary Parasitology

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12 November 2017

172

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3-4

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12 November 2017

291-298

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Drug transfer into target helminth parasites

12 November 2017

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Ketoconazole increases the plasma levels of ivermectin in sheep.

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Resistance to benzimidazole and macrocyclic lactone anthelmintics in cattle nematodes in Argentina

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Modulation of the P-glycoprotein-mediated intestinal secretion of ivermectin: in vitro and in vivo assessments.

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Involvement of P-glycoprotein on ivermectin kinetic behaviour in sheep: itraconazole-mediated changes on gastrointestinal disposition.

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The comparative serum disposition kinetics of subcutaneous administration of doramectin, ivermectin and moxidectin in the Australian Merino sheep.

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P-glycoprotein interfering agents potentiate ivermectin susceptibility in ivermectin sensitive and resistant isolates of Teladorsagia circumcincta and Haemonchus contortus.

7 January 2021

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Haemonchus contortus: selection at a glutamate-gated chloride channel gene in ivermectin- and moxidectin-selected strains

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World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) methods for the detection of anthelmintic resistance in nematodes of veterinary importance

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Satoshi Omura: in pursuit of nature's bounty

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Monitoring the efficacy of ivermectin and albendazole against gastro intestinal nematodes of cattle in Northern Europe

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Liquid chromatographic determination of ivermectin in animal plasma with trifluoroacetic anhydride and N-methylimidazole as the derivatization reagent

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Enhancement of moxidectin bioavailability in lamb by a natural flavonoid: quercetin.

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Comparative pharmacokinetics of ivermectin alone and a novel formulation of ivermectin and rafoxanide in calves and sheep

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Clinical efficacy assessment of the albendazole-ivermectin combination in lambs parasitized with resistant nematodes

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Ivermectin 20 years on: maturation of a wonder drug

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Comparative depletion of ivermectin and moxidectin milk residues in dairy sheep after oral and subcutaneous administration.

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Drug resistance in nematodes of veterinary importance: a status report.

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Analysis and partial reversal of multidrug resistance to anthelmintics due to P-glycoprotein in Haemonchus contortus eggs using Lens culinaris lectin

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Use of P-glycoprotein gene probes to investigate anthelmintic resistance in Haemonchus contortus and comparison with Onchocerca volvulus.

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Intestinal secretion is a major route for parent ivermectin elimination in the rat.

7 January 2021

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Interaction of macrocyclic lactones with P-glycoprotein: structure-affinity relationship

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Ivermectin disposition kinetics after subcutaneous and intramuscular administration of an oil-based formulation to cattle.

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Loperamide-induced enhancement of moxidectin availability in cattle

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Loperamide modifies the tissue disposition kinetics of ivermectin in rats

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Cattle nematodes resistant to macrocyclic lactones: comparative effects of P-glycoprotein modulation on the efficacy and disposition kinetics of ivermectin and moxidectin

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Drug-drug interaction mediated by inhibition and induction of P-glycoprotein.

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Reduced permeability in CHO cells as a mechanism of resistance to colchicine.

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Effects of the multidrug-resistance-reversing agents verapamil and CL 347,099 on the efficacy of ivermectin or moxidectin against unselected and drug-selected strains of Haemonchus contortus in jirds (Meriones unguiculatus).

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Influence of verapamil on the pharmacokinetics of the antiparasitic drugs ivermectin and moxidectin in sheep

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ABC transporters and beta-tubulin in macrocyclic lactone resistance: prospects for marker development

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Haemonchus contortus: sequence heterogeneity of internucleotide binding domains from P-glycoproteins.

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Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

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P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

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Ivermectin resistance in nematodes may be caused by alteration of P-glycoprotein homolog

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World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) second edition of guidelines for evaluating the efficacy of anthelmintics in ruminants (bovine, ovine, caprine)

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Drug resistance in veterinary helminths

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https://api.crossref.org/works/10.1016%2FJ.VETPAR.2010.04.039

10.1016/J.VETPAR.2010.04.039

7 January 2021

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12 November 2017

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