A novel pathway for adrenergic stimulation of cAMP-response-element-binding protein (CREB) phosphorylation: mediation via alpha1-adrenoceptors and protein kinase C activation. (Q43001675)

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scientific article published in May 2002

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English	A novel pathway for adrenergic stimulation of cAMP-response-element-binding protein (CREB) phosphorylation: mediation via alpha1-adrenoceptors and protein kinase C activation.	scientific article published in May 2002

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scholarly article

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10 December 2019

A novel pathway for adrenergic stimulation of cAMP-response-element-binding protein (CREB) phosphorylation: mediation via alpha1-adrenoceptors and protein kinase C activation (English)

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10 December 2019

phosphorylation

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Håkan Thonberg

1

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10 December 2019

J Magnus Fredriksson

2

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10 December 2019

Jan Nedergaard

3

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10 December 2019

Barbara Cannon

4

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10 December 2019

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1 May 2002

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10 December 2019

Biochemical Journal

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10 December 2019

364

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10 December 2019

Pt 1

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10 December 2019

73-79

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10 December 2019

beta-Adrenergic activation of p38 MAP kinase in adipocytes: cAMP induction of the uncoupling protein 1 (UCP1) gene requires p38 MAP kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

MSK1 is required for CREB phosphorylation in response to mitogens in mouse embryonic stem cells

1 reference

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26 May 2018

Calcium and cAMP signals differentially regulate cAMP-responsive element-binding protein function via a Rap1-extracellular signal-regulated kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Transcriptional activation of the human ucp1 gene in a rodent cell line. Synergism of retinoids, isoproterenol, and thiazolidinedione is mediated by a multipartite response element

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Transcriptional responses to growth factor and G protein-coupled receptors in PC12 cells: comparison of alpha(1)-adrenergic receptor subtypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Norepinephrine induces vascular endothelial growth factor gene expression in brown adipocytes through a beta -adrenoreceptor/cAMP/protein kinase A pathway involving Src but independently of Erk1/2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Beta 3- and alpha1-adrenergic Erk1/2 activation is Src- but not Gi-mediated in Brown adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Alpha 1-adrenoceptors: subtypes, signaling, and roles in health and disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

CREB activation induces adipogenesis in 3T3-L1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

beta1 to beta3 switch in control of cyclic adenosine monophosphate during brown adipocyte development explains distinct beta-adrenoceptor subtype mediation of proliferation and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

CREB-mediated transcriptional control.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Phosphorylation of the cAMP response element-binding protein and activation of transcription by alpha1 adrenergic receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Dominant negative regulation by c-Jun of transcription of the uncoupling protein-1 gene through a proximal cAMP-regulatory element: a mechanism for repressing basal and norepinephrine-induced expression of the gene before brown adipocyte differentia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Desensitization of the beta-adrenergic response in human brown adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

3',5'-cyclic adenosine monophosphate-response sequences of the uncoupling protein gene are sequentially recruited during darglitazone-induced brown adipocyte differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Neurotransmitter- and growth factor-induced cAMP response element binding protein phosphorylation in glial cell progenitors: role of calcium ions, protein kinase C, and mitogen-activated protein kinase/ribosomal S6 kinase pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

CREB phosphorylation and dephosphorylation: a Ca(2+)- and stimulus duration-dependent switch for hippocampal gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Norepinephrine as a morphogen?: its unique interaction with brown adipose tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Signaling pathways for antigen receptor-mediated induction of transcription factor CREB in B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Adrenergically activated Ca2+ increases in brown fat cells: effects of Ca2+, K+, and K channel block

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Identification of tissue-specific protein binding domains in the 5'-proximal regulatory region of the rat mitochondrial brown fat uncoupling protein gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Insulin and growth factor effects on c-fos expression in normal and protein kinase C-deficient 3T3-L1 fibroblasts and adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Phorbol esters, protein kinase C, and thyroxine 5'-deiodinase in brown adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Multiple second messenger pathways of alpha-adrenergic receptor subtypes expressed in eukaryotic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Expression of four protein kinase C isoforms in rat fibroblasts. Distinct subcellular distribution and regulation by calcium and phorbol esters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

26 May 2018

Analysis of inhibition by H89 of UCP1 gene expression and thermogenesis indicates protein kinase A mediation of beta(3)-adrenergic signalling rather than beta(3)-adrenoceptor antagonism by H89.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

16 August 2018

An upstream enhancer regulating brown-fat-specific expression of the mitochondrial uncoupling protein gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1222547

16 August 2018

Activation of mitogen-activated protein kinase by norepinephrine in brown adipocytes from rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11988078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A dual component analysis explains the distinctive kinetics of cAMP accumulation in brown adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11988078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related changes in the control of hepatic cyclic AMP levels by alpha 1- and beta 2-adrenergic receptors in male rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11988078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of brown fat cells in monolayer culture. I. Morphological and biochemical distinction from white fat cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/11988078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha 1- and beta-adrenergic regulation of intracellular Ca2+ levels in brown adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11988078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-adrenergic, cAMP-mediated stimulation of proliferation of brown fat cells in primary culture. Mediation via beta 1 but not via beta 3 adrenoceptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11988078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coupling of expressed alpha 1B- and alpha 1D-adrenergic receptor to multiple signaling pathways is both G protein and cell type specific

1 reference

https://pubmed.ncbi.nlm.nih.gov/11988078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Norepinephrine utilizes alpha 1- and beta-adrenoreceptors synergistically to maximally induce c-fos expression in brown adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11988078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C mediates activation of nuclear cAMP response element-binding protein (CREB) in B lymphocytes stimulated through surface Ig

1 reference

https://pubmed.ncbi.nlm.nih.gov/11988078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A protein kinase C-, Ras-, and RSK2-dependent signal transduction pathway activates the cAMP-responsive element-binding protein transcription factor following T cell receptor engagement

1 reference

https://pubmed.ncbi.nlm.nih.gov/11988078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ambient temperature regulation of apoptosis in brown adipose tissue. Erk1/2 promotes norepinephrine-dependent cell survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/11988078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of functional responses by beta-adrenergic receptor subtypes in brown adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11988078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signal transduction in brown adipose tissue recruitment: noradrenaline and beyond

1 reference

https://pubmed.ncbi.nlm.nih.gov/11988078

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3640073

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11988078%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11988078%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11988078%20AND%20SRC:MED&resulttype=core&format=json

10 December 2019

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