The pro-urokinase plasminogen-activation system in the presence of serpin-type inhibitors and the urokinase receptor: rescue of activity through reciprocal pro-enzyme activation. (Q43002806)

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scientific article published in April 2003

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English	The pro-urokinase plasminogen-activation system in the presence of serpin-type inhibitors and the urokinase receptor: rescue of activity through reciprocal pro-enzyme activation.	scientific article published in April 2003

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scholarly article

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16 December 2019

The pro-urokinase plasminogen-activation system in the presence of serpin-type inhibitors and the urokinase receptor: rescue of activity through reciprocal pro-enzyme activation (English)

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16 December 2019

1

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16 December 2019

author name string

Karin List

2

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16 December 2019

Peter A Andreasen

3

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16 December 2019

Keld Danø

4

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16 December 2019

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publication date

1 April 2003

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16 December 2019

Biochemical Journal

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16 December 2019

371

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16 December 2019

Pt 2

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16 December 2019

277-287

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16 December 2019

Serpins and other covalent protease inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

Elements of the fibrinolytic system

1 reference

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26 May 2018

Structure of a serpin-protease complex shows inhibition by deformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

Urokinase-type plasminogen activator and its receptor synergize to promote pathogenic proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

The plasminogen activation system in tumor growth, invasion, and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

A urokinase receptor-associated protein with specific collagen binding properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

Cancer invasion and tissue remodeling--cooperation of protease systems and cell types.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

The urokinase-type plasminogen activator system in cancer metastasis: A review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

Domain interplay in the urokinase receptor. Requirement for the third domain in high affinity ligand binding and demonstration of ligand contact sites in distinct receptor domains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

Urokinase-type plasminogen activator is effective in fibrin clearance in the absence of its receptor or tissue-type plasminogen activator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

Single-chain urokinase-type plasminogen activator bound to its receptor is relatively resistant to plasminogen activator inhibitor type 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

Cellular receptor for urokinase-type plasminogen activator: function in cell-surface proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

Plasminogen Activator Released as Inactive Proenzyme from Murine Cells Transformed by Sarcoma Virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

Plasminogen activator inhibitor from human fibrosarcoma cells binds urokinase-type plasminogen activator, but not its proenzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

One-chain urokinase-type plasminogen activator from human sarcoma cells is a proenzyme with little or no intrinsic activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

Plasminogen activators, tissue degradation, and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

Plasminogen activation initiated by single-chain urokinase-type plasminogen activator. Potentiation by U937 monocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

Inhibition of receptor-bound urokinase by plasminogen-activator inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

Porcine pancreatic cationic pro-elastase. Studies on the activation, turnover and interaction with plasma proteinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

Plasminogen activation by receptor-bound urokinase. A kinetic study with both cell-associated and isolated receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

Plasminogen Activation by Receptor-Bound Urokinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

Formation of a stable complex between human proelastase 2 and human alpha 1-protease inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

The inhibition mechanism of serpins. Evidence that the mobile reactive center loop is cleaved in the native protease-inhibitor complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

26 May 2018

Purification of zymogen to plasminogen activator from human glioblastoma cells by affinity chromatography with monoclonal antibody.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

3 July 2018

Heterogeneity in serpin-protease complexes as demonstrated by differences in the mechanism of complex breakdown

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

16 August 2018

Localization of epitopes for monoclonal antibodies to urokinase-type plasminogen activator: relationship between epitope localization and effects of antibodies on molecular interactions of the enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

16 August 2018

An ester bond linking a fragment of a serine proteinase to its serpin inhibitor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

16 August 2018

Kinetics of reciprocal pro-urokinase/plasminogen activation--stimulation by a template formed by the urokinase receptor bound to poly(D-lysine).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

16 August 2018

Plasminogen-independent initiation of the pro-urokinase activation cascade in vivo. Activation of pro-urokinase by glandular kallikrein (mGK-6) in plasminogen-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1223308

1 December 2018

Characterization of the binding of urokinase-type plasminogen activator (u-PA) to plasminogen, to plasminogen-activator inhibitor-1 and to the u-PA receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of the enzymatic activity of single-chain urokinase plasminogen activator by soluble urokinase receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of single-chain urokinase and plasminogen activator inhibitor type 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serpin-protease complexes are trapped as stable acyl-enzyme intermediates

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional analysis of the cellular receptor for urokinase in plasminogen activation. Receptor binding has no influence on the zymogenic nature of pro-urokinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of purified, soluble urokinase receptor on the plasminogen-prourokinase activation system

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Commentary on: 'Effect of purified soluble urokinase receptor on the plasminogen prourokinase activation system' by N. Behrendt and K. Dano, FEBS Letters, 393 (1996) 31-36

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reply to comment on 'Effect of purified, soluble urokinase receptor on the plasminogen-prourokinase activation system' (A. A-R. Higazi)

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostatic kallikrein hK2, but not prostate-specific antigen (hK3), activates single-chain urokinase-type plasminogen activator

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Urokinase receptor-associated protein (uPARAP) is expressed in connection with malignant as well as benign lesions of the human breast and occurs in specific populations of stromal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transition of bovine trypsinogen to a trypsin-like state upon strong ligand binding. The refined crystal structures of the bovine trypsinogen-pancreatic trypsin inhibitor complex and of its ternary complex with Ile-Val at 1.9 A resolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction of chymotrypsinogens with alpha 1-protease inhibitor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The activation of pro-urokinase by plasma kallikrein and its inactivation by thrombin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibodies to human 54,000 molecular weight plasminogen activator inhibitor from fibrosarcoma cells--inhibitor neutralization and one-step affinity purification

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enzyme-linked immunosorbent assay for human urokinase-type plasminogen activator and its proenzyme using a combination of monoclonal and polyclonal antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The control of the urokinase-catalyzed activation of human glutamic acid 1-plasminogen by positive and negative effectors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cathepsin B efficiently activates the soluble and the tumor cell receptor-bound form of the proenzyme urokinase-type plasminogen activator (Pro-uPA)

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a tetrahedral intermediate complex during serpin-proteinase interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potentiation of plasminogen activation by an anti-urokinase monoclonal antibody due to ternary complex formation. A mechanistic model for receptor-mediated plasminogen activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human mast cell tryptase activates single-chain urinary-type plasminogen activator (pro-urokinase)

1 reference

https://pubmed.ncbi.nlm.nih.gov/12534347

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ20021508

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12534347%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

PMC publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12534347%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12534347%20AND%20SRC:MED&resulttype=core&format=json

16 December 2019

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