Deoxynucleoside salvage enzymes and tissue specific mitochondrial DNA depletion (Q43026538)

12 November 2017

Deoxynucleoside salvage enzymes and tissue specific mitochondrial DNA depletion (English)

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12 November 2017

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L Wang

1

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12 November 2017

1 June 2010

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Nucleosides, Nucleotides & Nucleic Acids

12 November 2017

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12 November 2017

29

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12 November 2017

4-6

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12 November 2017

370-381

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Molecular mechanisms of mitochondrial DNA depletion diseases caused by deficiencies in enzymes in purine and pyrimidine metabolism

12 November 2017

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Progressive loss of mitochondrial DNA in thymidine kinase 2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Thymidine kinase 2 (H126N) knockin mice show the essential role of balanced deoxynucleotide pools for mitochondrial DNA maintenance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

DNA replication and transcription in mammalian mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Twinkle helicase is essential for mtDNA maintenance and regulates mtDNA copy number

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Mouse models of mitochondrial DNA defects and their relevance for human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

The conserved Mec1/Rad53 nuclear checkpoint pathway regulates mitochondrial DNA copy number in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Regulation of mammalian ribonucleotide reduction and dNTP pools after DNA damage and in resting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Mutation of RRM2B, encoding p53-controlled ribonucleotide reductase (p53R2), causes severe mitochondrial DNA depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Loss of p53 causes mitochondrial DNA depletion and altered mitochondrial reactive oxygen species homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Rapid and random turnover of mitochondrial DNA in rat hepatocytes of primary culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Identification of the mitochondrial targeting signal of the human equilibrative nucleoside transporter 1 (hENT1): implications for interspecies differences in mitochondrial toxicity of fialuridine

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Altered gene transcription profiles in fibroblasts harboring either TK2 or DGUOK mutations indicate compensatory mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Facilitated mitochondrial import of antiviral and anticancer nucleoside drugs by human equilibrative nucleoside transporter-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Phosphorylation of thymidine and AZT in heart mitochondria: elucidation of a novel mechanism of AZT cardiotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Immunocytochemical detection of hENT1 and hCNT1 in normal tissues, lung cancer cell lines, and NSCLC patient samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Maintaining precursor pools for mitochondrial DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Mitochondrial deoxynucleotide pool sizes in mouse liver and evidence for a transport mechanism for thymidine monophosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Expression of deoxynucleoside kinases and 5'-nucleotidases in mouse tissues: implications for mitochondrial toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

DNA precursor asymmetries in mammalian tissue mitochondria and possible contribution to mutagenesis through reduced replication fidelity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Mitochondrial deoxyribonucleotide pools in deoxyguanosine kinase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Kinetic properties of mutant human thymidine kinase 2 suggest a mechanism for mitochondrial DNA depletion myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Origin of pyrimidine deoxyribonucleotide pools in perfused rat heart: implications for 3'-azido-3'-deoxythymidine-dependent cardiotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

Mitochondrial deoxynucleotide pools in quiescent fibroblasts: a possible model for mitochondrial neurogastrointestinal encephalomyopathy (MNGIE).

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F15257771003729732

10.1080/15257771003729732

21 January 2018

Identifiers

DOI

1 reference

12 November 2017

1 reference

PubMed ID

20544522