Identification of a unique subset of 2-methylene-19-nor analogs of vitamin D with comedolytic activity in the rhino mouse (Q43036697)

12 November 2017

Identification of a unique subset of 2-methylene-19-nor analogs of vitamin D with comedolytic activity in the rhino mouse (English)

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12 November 2017

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4

Hector F DeLuca

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12 November 2017

Nirca J Nieves

1

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12 November 2017

Jamie M Ahrens

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2

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12 November 2017

Lori A Plum

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3

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12 November 2017

Margaret Clagett-Dame

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5

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12 November 2017

language of work or name

English

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publication date

10 June 2010

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Journal of Investigative Dermatology

12 November 2017

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12 November 2017

130

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12 November 2017

10

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12 November 2017

2359-2367

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https://scigraph.springernature.com/pub.10.1038/jid.2010.142

12 November 2017

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Histologic changes in the skin of the rhino mouse (hrrhhrrh) induced by retinoids

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Removal of the 20-methyl group from 2-methylene-19-nor-(20S)-1alpha,25-dihydroxyvitamin D(3) (2MD) selectively eliminates bone calcium mobilization activity

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7 January 2021

Sequence of morphological events during topical application of retinoic acid on the rhino mouse skin

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The rhino mouse model: the effects of topically applied all-trans retinoic acid and CD271 on the fine structure of the epidermis and utricle wall of pseudocomedones

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Quantification of Epidermal Histological Changes Induced by Topical Retinoids and CD271 in the Rhino Mouse Model Using a Standardized Image Analysis Technique

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7 January 2021

Pharmacotherapy of acne

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7 January 2021

Evolution of our understanding of vitamin D.

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7 January 2021

Selective analogs of 1alpha,25-dihydroxyvitamin D3 for the study of specific functions of Vitamin D

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7 January 2021

Comedolytic effect of topical retinaldehyde in the rhino mouse model

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7 January 2021

Epidermal change can alter mechanical properties of hairless mouse skin topically treated with 1alpha, 25-dihydroxyvitamin D(3)

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7 January 2021

Stimulation versus inhibition of keratinocyte growth by 1,25-Dihydroxyvitamin D3: dependence on cell culture conditions

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The effects of KH 1060, a potent 20-epi analogue of the vitamin D3 hormone, on hairless mouse skin in vivo

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Stimulation of epidermal proliferation in mice with 1 alpha, 25-dihydroxyvitamin D3 and receptor-active 20-EPI analogues of 1 alpha, 25-dihydroxyvitamin D3

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Current concepts of the pathogenesis of acne: implications for drug treatment

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Vitamin D receptor: molecular signaling and actions of nutritional ligands in disease prevention

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7 January 2021

Comedolytic effect of topically applied active vitamin D3 analogue on pseudocomedones in the rhino mouse

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7 January 2021

McCollum Award Lecture, 1994: vitamin D--new horizons for the 21st century

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7 January 2021

Regulation of Terminal Differentiation of Cultured Mouse Epidermal Cells by lα,25-Dihydroxyvitamin D3*

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7 January 2021

Physical and functional interaction between the vitamin D receptor and hairless corepressor, two proteins required for hair cycling

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7 January 2021

Current understanding of the molecular actions of vitamin D.

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The Effect on Rhino Mouse Skin of Agents which Influence Keratinization and Exfoliation

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Characterization of the vitamin D endocrine system in human sebocytes in vitro

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Topical calcitriol in the treatment of chronic plaque psoriasis: a double-blind study

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Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia

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7 January 2021

Hair loss and cyst formation in hairless and rhino mutant mice

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7 January 2021

Topical and Systemic Effects of Retinoids on Horn-Filled Utriculus Size in the Rhino Mouse. A Model to Quantify “Antikeratinizing” Effects of Retinoids

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7 January 2021

Models in acnegenesis

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7 January 2021

Phase II trial of oral 1,25-dihydroxyvitamin D (calcitriol) in hormone refractory prostate cancer

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7 January 2021

Biologically active noncalcemic analogs of 1alpha,25-dihydroxyvitamin D with an abbreviated side chain containing no hydroxyl

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7 January 2021

Biologic effects of topical calcipotriol (MC 903) treatment in psoriatic skin

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7 January 2021

The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand

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7 January 2021

New 1alpha,25-dihydroxy-19-norvitamin D3 compounds of high biological activity: synthesis and biological evaluation of 2-hydroxymethyl, 2-methyl, and 2-methylene analogues

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7 January 2021

New highly calcemic 1 alpha,25-dihydroxy-19-norvitamin D(3) compounds with modified side chain: 26,27-dihomo- and 26,27-dimethylene analogs in 20S-series

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7 January 2021

Ligand-independent actions of the vitamin D receptor maintain hair follicle homeostasis

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7 January 2021

Target cells for 1,25-dihydroxyvitamin D3 in intestinal tract, stomach, kidney, skin, pituitary, and parathyroid

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https://api.crossref.org/works/10.1038%2FJID.2010.142

7 January 2021

Crystal structures of the vitamin D receptor complexed to superagonist 20-epi ligands

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7 January 2021

Molecular structure of the rat vitamin D receptor ligand binding domain complexed with 2-carbon-substituted vitamin D3 hormone analogues and a LXXLL-containing coactivator peptide

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.142

7 January 2021

New analogs of 2-methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 with conformationally restricted side chains: evaluation of biological activity and structural determination of VDR-bound conformations

1 reference

https://api.crossref.org/works/10.1038%2FJID.2010.142

7 January 2021

Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning

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https://api.crossref.org/works/10.1038%2FJID.2010.142

7 January 2021

The co-repressor hairless has a role in epithelial cell differentiation in the skin.

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https://api.crossref.org/works/10.1038%2FJID.2010.142

7 January 2021

Identifiers

DOI

10.1038/JID.2010.142

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12 November 2017

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