The serine protease domain of hepatitis C viral NS3 activates RNA helicase activity by promoting the binding of RNA substrate (Q43041225)

12 November 2017

The serine protease domain of hepatitis C viral NS3 activates RNA helicase activity by promoting the binding of RNA substrate (English)

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12 November 2017

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Rudolf K F Beran

1

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12 November 2017

Victor Serebrov

series ordinal

2

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12 November 2017

Anna Marie Pyle

series ordinal

3

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12 November 2017

language of work or name

English

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publication date

5 October 2007

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Journal of Biological Chemistry

12 November 2017

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12 November 2017

282

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12 November 2017

34913-34920

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12 November 2017

48

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Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase

12 November 2017

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

The nonstructural protein 3 protease/helicase requires an intact protease domain to unwind duplex RNA efficiently

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

A Brownian motor mechanism of translocation and strand separation by hepatitis C virus helicase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

Stimulation of hepatitis C virus (HCV) nonstructural protein 3 (NS3) helicase activity by the NS3 protease domain and by HCV RNA-dependent RNA polymerase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

Hepatitis C Virus NS3 ATPases/Helicases from Different Genotypes Exhibit Variations in Enzymatic Properties

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

Structure of the hepatitis C virus RNA helicase domain

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707165200

Modulation of the hepatitis C virus RNA-dependent RNA polymerase activity by the non-structural (NS) 3 helicase and the NS4B membrane protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707165200

Compensatory Mutations in E1, p7, NS2, and NS3 Enhance Yields of Cell Culture-Infectious Intergenotypic Chimeric Hepatitis C Virus

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

Role of Divalent Metal Cations in ATP Hydrolysis Catalyzed by the Hepatitis C Virus NS3 Helicase: Magnesium Provides a Bridge for ATP to Fuel Unwinding

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

Halogenated benzimidazoles and benzotriazoles as inhibitors of the NTPase/helicase activities of hepatitis C and related viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707165200

The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

Ribonuclease E organizes the protein interactions in the Escherichia coli RNA degradosome

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

Activation of the DExD/H-box protein Dbp5 by the nuclear-pore protein Gle1 and its coactivator InsP6 is required for mRNA export

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707165200

The nucleolar protein Esf2 interacts directly with the DExD/H box RNA helicase, Dbp8, to stimulate ATP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707165200

Ntr1 activates the Prp43 helicase to trigger release of lariat-intron from the spliceosome

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

Robust translocation along a molecular monorail: the NS3 helicase from hepatitis C virus traverses unusually large disruptions in its track

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707165200

Periodic cycles of RNA unwinding and pausing by hepatitis C virus NS3 helicase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

A double-filter method for nitrocellulose-filter binding: application to protein-nucleic acid interactions

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

A DEAD-box RNA helicase in the Escherichia coli RNA degradosome

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

Reconstitution of a minimal RNA degradosome demonstrates functional coordination between a 3' exonuclease and a DEAD-box RNA helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707165200

ExPASy: The proteomics server for in-depth protein knowledge and analysis

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

Mutational analysis of the Escherichia coli DEAD box protein CsdA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707165200

The DExH protein NPH-II is a processive and directional motor for unwinding RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707165200

Multiple full-length NS3 molecules are required for optimal unwinding of oligonucleotide DNA in vitro

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

Backbone tracking by the SF2 helicase NPH-II.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

In vitro studies of cross-resistance mutations against two hepatitis C virus serine protease inhibitors, VX-950 and BILN 2061.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707165200

Regulation of Interferon Regulatory Factor-3 by the Hepatitis C Virus Serine Protease

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

Hepatitis C virus subgenomic replicon requires an active NS3 RNA helicase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

The C Terminus of Hepatitis C Virus NS4A Encodes an Electrostatic Switch That Regulates NS5A Hyperphosphorylation and Viral Replication

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

Spring-loaded mechanism of DNA unwinding by hepatitis C virus NS3 helicase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M707165200

Structural basis for DNA duplex separation by a superfamily-2 helicase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707165200

Escherichia coli DbpA is an RNA helicase that requires hairpin 92 of 23S rRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707165200

Complex formation of NS5B with NS3 and NS4A proteins of hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707165200

Identification of Determinants Involved in Initiation of Hepatitis C Virus RNA Synthesis by Using Intergenotypic Replicase Chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707165200

21 January 2018

Identifiers

DOI

10.1074/JBC.M707165200

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12 November 2017

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