An NS3 serine protease inhibitor abrogates replication of subgenomic hepatitis C virus RNA. (Q43049197)

12 November 2017

An NS3 serine protease inhibitor abrogates replication of subgenomic hepatitis C virus RNA. (English)

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12 November 2017

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9

Martin Marquis

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12 November 2017

2

George Kukolj

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12 November 2017

10

Ginette McKercher

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12 November 2017

Arnim Pause

1

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12 November 2017

Murray Bailey

3

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12 November 2017

Martine Brault

4

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12 November 2017

Florence Dô

5

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12 November 2017

Ted Halmos

6

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12 November 2017

Lisette Lagacé

7

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12 November 2017

Roger Maurice

8

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12 November 2017

Charles Pellerin

11

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12 November 2017

Louise Pilote

12

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12 November 2017

Diane Thibeault

13

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12 November 2017

Daniel Lamarre

14

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12 November 2017

language of work or name

English

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publication date

19 March 2003

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Journal of Biological Chemistry

12 November 2017

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12 November 2017

278

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12 November 2017

22

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12 November 2017

20374-20380

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Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome

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Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

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The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site

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Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide

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Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase

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The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism

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Structural characterization of the interactions of optimized product inhibitors with the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein by NMR and modelling studies

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Solution structure of substrate-based ligands when bound to hepatitis C virus NS3 protease domain.

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Product inhibition of the hepatitis C virus NS3 protease

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Peptide-based inhibitors of the hepatitis C virus serine protease

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Highly potent and selective peptide-based inhibitors of the hepatitis C virus serine protease: towards smaller inhibitors.

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Solid-phase synthesis of peptidomimetic inhibitors for the hepatitis C virus NS3 protease

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A continuous assay of hepatitis C virus protease based on resonance energy transfer depsipeptide substrates

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In vitro characterization of a purified NS2/3 protease variant of hepatitis C virus

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Modulation of hepatitis C virus NS3 protease and helicase activities through the interaction with NS4A

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Efficient initiation of HCV RNA replication in cell culture

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Interferon-alpha inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway

21 January 2018

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Effect of alpha interferon on the hepatitis C virus replicon

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Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation

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Interferon inhibits dengue virus infection by preventing translation of viral RNA through a PKR-independent mechanism

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Activation and evasion of the antiviral 2'-5' oligoadenylate synthetase/ribonuclease L pathway by hepatitis C virus mRNA.

21 January 2018

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To interfere and to anti-interfere: the interplay between hepatitis C virus and interferon.

21 January 2018

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Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3' nontranslated region are essential for virus replication in vivo

21 January 2018

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Novel approaches to the treatment of hepatitis C virus infection

21 January 2018

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Prime site binding inhibitors of a serine protease: NS3/4A of hepatitis C virus

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Azapeptides as inhibitors of the hepatitis C virus NS3 serine protease

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Pyrrolidine-5,5-trans-lactams. 1. Synthesis and incorporation into inhibitors of hepatitis C virus NS3/4A protease

21 January 2018

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Isolation and characterization of RNA aptamers specific for the hepatitis C virus nonstructural protein 3 protease

21 January 2018

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Isolation of RNA aptamers specific to the NS3 protein of hepatitis C virus from a pool of completely random RNA.

21 January 2018

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Identification and biological characterization of heterocyclic inhibitors of the hepatitis C virus RNA-dependent RNA polymerase

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Persistent Replication of Hepatitis C Virus Replicons Expressing the -Lactamase Reporter in Subpopulations of Highly Permissive Huh7 Cells

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21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M210785200

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12 November 2017

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