Profiling Protein Arginine Deiminase 4 (PAD4): a novel screen to identify PAD4 inhibitors (Q43076584)

13 November 2017

Profiling Protein Arginine Deiminase 4 (PAD4): a novel screen to identify PAD4 inhibitors (English)

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13 November 2017

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ChEBI release 2020-05-28

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13 November 2017

Yuan Luo

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13 November 2017

Paul R Thompson

series ordinal

3

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13 November 2017

language of work or name

English

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publication date

13 October 2007

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Bioorganic & Medicinal Chemistry

13 November 2017

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13 November 2017

16

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13 November 2017

2

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13 November 2017

739-745

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Protein arginine deiminase 4: evidence for a reverse protonation mechanism

13 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

Histone citrullination by protein arginine deiminase: is arginine methylation a green light or a roadblock?

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

Activity-based protein profiling reagents for protein arginine deiminase 4 (PAD4): synthesis and in vitro evaluation of a fluorescently labeled probe

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

Inhibitors and inactivators of protein arginine deiminase 4: functional and structural characterization.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

Minocycline inhibits poly(ADP-ribose) polymerase-1 at nanomolar concentrations.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

Association between PADI4 and rheumatoid arthritis: a meta-analysis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

A fluoroacetamidine-based inactivator of protein arginine deiminase 4: design, synthesis, and in vitro and in vivo evaluation

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

Kinetic characterization of protein arginine deiminase 4: a transcriptional corepressor implicated in the onset and progression of rheumatoid arthritis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

Citrullinated proteins have increased immunogenicity and arthritogenicity and their presence in arthritic joints correlates with disease severity

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

Newer approaches to the treatment of rheumatoid arthritis.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

Therapeutic strategies for rheumatoid arthritis

25 May 2018

1 reference

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Discovering potent and selective reversible inhibitors of enzymes in complex proteomes

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

Inhibition of trypsin-like cysteine proteinases (gingipains) from Porphyromonas gingivalis by tetracycline and its analogues

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

Antibiotic therapy for rheumatoid arthritis. Scientific and anecdotal appraisals

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

ABC of rheumatology. Rheumatoid arthritis--I: Clinical features and diagnosis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

A non-antibacterial chemically-modified tetracycline inhibits mammalian collagenase activity

25 May 2018

1 reference

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A functional proteomic strategy to discover inhibitors for uncharacterized hydrolases

25 May 2018

1 reference

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Single-blind randomized trial of combination antibiotic therapy in rheumatoid arthritis.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

A continuous spectrophotometric assay method for peptidylarginine deiminase type 4 activity

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

Discovery of an exceptionally potent and selective class of fatty acid amide hydrolase inhibitors enlisting proteome-wide selectivity screening: concurrent optimization of enzyme inhibitor potency and selectivity

15 August 2018

1 reference

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The diagnostic properties of rheumatoid arthritis antibodies recognizing a cyclic citrullinated peptide

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

The epitopes targeted by the rheumatoid arthritis-associated antifilaggrin autoantibodies are posttranslationally generated on various sites of (pro)filaggrin by deimination of arginine residues

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2267747

ABAP: antibody-based assay for peptidylarginine deiminase activity

15 August 2018

1 reference

12 December 2020

Effect of tetracycline on the phagocytic function of human leukocytes

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12 December 2020

Minocycline reduces gingival collagenolytic activity during diabetes. Preliminary observations and a proposed new mechanism of action

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12 December 2020

Tetracyclines inhibit human synovial collagenase in vivo and in vitro

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12 December 2020

Should tetracyclines be used in arthritis?

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12 December 2020

PADI4 polymorphisms and rheumatoid arthritis susceptibility: a meta-analysis

1 reference

12 December 2020

A colorimetric 96-well microtiter plate assay for the determination of enzymatically formed citrulline

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12 December 2020

10.1016/J.BMC.2007.10.021

Identifiers

DOI

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13 November 2017

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13 November 2017

PubMed publication ID

17964793

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