Interplay of dissolution, solubility, and nonsink permeation determines the oral absorption of the Hedgehog pathway inhibitor GDC-0449 in dogs: an investigation using preclinical studies and physiologically based pharmacokinetic modeling (Q43091655)
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scientific article published on 20 April 2010
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English | Interplay of dissolution, solubility, and nonsink permeation determines the oral absorption of the Hedgehog pathway inhibitor GDC-0449 in dogs: an investigation using preclinical studies and physiologically based pharmacokinetic modeling |
scientific article published on 20 April 2010 |
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Interplay of dissolution, solubility, and nonsink permeation determines the oral absorption of the Hedgehog pathway inhibitor GDC-0449 in dogs: an investigation using preclinical studies and physiologically based pharmacokinetic modeling (English)
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Harvey Wong
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Frank-Peter Theil
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Yong Cui
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James C Marsters
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S Cyrus Khojasteh
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Laurent Vernillet
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Hank La
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Xiling Song
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Hong Wang
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Eric J Morinello
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Yuzhong Deng
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Cornelis E C A Hop
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20 April 2010
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38
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7
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1029-1038
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Identifiers
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