Peroxisome proliferator-activated receptor delta agonists inhibit T helper type 1 (Th1) and Th17 responses in experimental allergic encephalomyelitis (Q43091964)

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scientific article published on 6 April 2010

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English	Peroxisome proliferator-activated receptor delta agonists inhibit T helper type 1 (Th1) and Th17 responses in experimental allergic encephalomyelitis	scientific article published on 6 April 2010

Statements

scholarly article

1 reference

Europe PubMed Central

13 November 2017

Peroxisome proliferator-activated receptor delta agonists inhibit T helper type 1 (Th1) and Th17 responses in experimental allergic encephalomyelitis (English)

1 reference

Europe PubMed Central

13 November 2017

author name string

Saravanan Kanakasabai

1

1 reference

Europe PubMed Central

13 November 2017

Wanida Chearwae

2

1 reference

Europe PubMed Central

13 November 2017

Crystal C Walline

3

1 reference

Europe PubMed Central

13 November 2017

Wade Iams

4

1 reference

Europe PubMed Central

13 November 2017

Suzanne M Adams

5

1 reference

Europe PubMed Central

13 November 2017

John J Bright

6

1 reference

Europe PubMed Central

13 November 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

6 April 2010

1 reference

Europe PubMed Central

13 November 2017

1 reference

Europe PubMed Central

13 November 2017

130

1 reference

Europe PubMed Central

13 November 2017

572-588

1 reference

Europe PubMed Central

13 November 2017

4

1 reference

Europe PubMed Central

13 November 2017

Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2010.03261.X

21 January 2018

IL-23 produced by CNS-resident cells controls T cell encephalitogenicity during the effector phase of experimental autoimmune encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2010.03261.X

21 January 2018

Peroxisome proliferator-activated receptor alpha agonists as therapy for autoimmune disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2010.03261.X

21 January 2018

Stat4 isoforms differentially regulate inflammation and demyelination in experimental allergic encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2010.03261.X

21 January 2018

Immunoregulation of encephalitogenic MBP-NAc1-11-reactive T cells by CD4+ TCR-specific T cells involves IL-4, IL-10 and IFN-gamma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2567.2010.03261.X

21 January 2018

The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Role of peroxisome-proliferator-activated receptor beta/delta (PPARbeta/delta) in gastrointestinal tract function and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Role of Th1 and Th17 cells in organ-specific autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

PPARdelta-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Protective effects of a peroxisome proliferator-activated receptor-beta/delta agonist in experimental autoimmune encephalomyelitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

PPARgamma antagonists exacerbate neural antigen-specific Th1 response and experimental allergic encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

The PPARdelta agonist GW0742X reduces atherosclerosis in LDLR(-/-) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Quercetin, a flavonoid phytoestrogen, ameliorates experimental allergic encephalomyelitis by blocking IL-12 signaling through JAK-STAT pathway in T lymphocyte

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

IL-4 is the key regulator in herpes simplex virus-based gene therapy of BALB/c experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

The IL-12 family of heterodimeric cytokines: new players in the regulation of T cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Localization of PPARdelta in murine central nervous system: expression in oligodendrocytes and neurons.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Amelioration of experimental autoimmune encephalomyelitis in C57BL/6 mice by an agonist of peroxisome proliferator-activated receptor-gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

PPAR delta agonists stimulate oligodendrocyte differentiation in tissue culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Growth, adipose, brain, and skin alterations resulting from targeted disruption of the mouse peroxisome proliferator-activated receptor beta(delta)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

A gender gap in autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Differential influence of interleukin-12 in the pathogenesis of autoimmune and virus-induced central nervous system demyelination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Expression of IL-12 in CNS and lymphoid organs of mice with experimental allergic encephalitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Interleukin-12 induces relapse in experimental allergic encephalomyelitis in the Lewis rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Interleukin 12 administration induces T helper type 1 cells and accelerates autoimmune diabetes in NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

The role of IL-12 in the induction of organ-specific autoimmune diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Prevention of experimental autoimmune encephalomyelitis by antibodies against interleukin 12.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2913268

3 November 2018

Peroxisome proliferator-activated receptor alpha, delta, gamma1 and gamma2 expressions are present in human monocyte-derived dendritic cells and modulate dendritic cell maturation by addition of subtype-specific ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/20406305

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1,25 dihydroxyvitamin-D3 modulates JAK–STAT pathway in IL-12/IFNγ axis leading to Th1 response in experimental allergic encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20406305

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-23 is critical in the induction but not in the effector phase of experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20406305

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-23-driven encephalo-tropism and Th17 polarization during CNS-inflammation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20406305

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-gamma-deficient heterozygous mice develop an exacerbated neural antigen-induced Th1 response and experimental allergic encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20406305

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20406305

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of Th1 development and treatment of chronic-relapsing experimental allergic encephalomyelitis by a non-hypercalcemic analogue of 1,25-dihydroxyvitamin D(3)

1 reference

https://pubmed.ncbi.nlm.nih.gov/20406305

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxisome proliferator-activated receptor-gamma agonist 15-deoxy-Delta(12,14)-prostaglandin J(2) ameliorates experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20406305

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated serum levels of interleukin-12 in chronic progressive multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20406305

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Member of the peroxisome proliferator-activated receptor family of transcription factors is differentially expressed by oligodendrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20406305

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lack of Th2 cytokine increase during spontaneous remission of experimental allergic encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20406305

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPARgamma antagonists reverse the inhibition of neural antigen-specific Th1 response and experimental allergic encephalomyelitis by Ciglitazone and 15-deoxy-Delta12,14-prostaglandin J2

1 reference

https://pubmed.ncbi.nlm.nih.gov/20406305

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2567.2010.03261.X

1 reference

Europe PubMed Central

13 November 2017

0 references

1 reference

Europe PubMed Central

13 November 2017

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