Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease. (Q43107476)

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scientific article published in April 2010

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English	Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease.	scientific article published in April 2010

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30 January 2020

Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease (English)

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30 January 2020

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metabolic dysfunction–associated steatotic liver disease

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30 January 2020

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30 January 2020

Raffaela Rametta

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30 January 2020

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30 January 2020

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Ahmad Al-Serri

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30 January 2020

Enrico Galmozzi

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30 January 2020

Paola Dongiovanni

6

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30 January 2020

Giancarlo Roviaro

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30 January 2020

Ester Vanni

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30 January 2020

Marco Maggioni

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30 January 2020

Anna Ludovica Fracanzani

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30 January 2020

Silvia Fargion

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30 January 2020

Christopher P Day

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30 January 2020

Elisabetta Bugianesi

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1 April 2010

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30 January 2020

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30 January 2020

51

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30 January 2020

1209-1217

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30 January 2020

4

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30 January 2020

Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity

1 reference

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Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent

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Characterization of the human patatin-like phospholipase family

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Adiponutrin, a transmembrane protein corresponding to a novel dietary- and obesity-linked mRNA specifically expressed in the adipose lineage

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21 January 2018

The expression level of non-alcoholic fatty liver disease-related gene PNPLA3 in hepatocytes is highly influenced by hepatic lipid status.

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A sequence variation (I148M) in PNPLA3 associated with nonalcoholic fatty liver disease disrupts triglyceride hydrolysis

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A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity.

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A common variant in PNPLA3, which encodes adiponutrin, is associated with liver fat content in humans

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Polymorphisms in the adiponutrin gene are associated with increased insulin secretion and obesity

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Inhibiting triglyceride synthesis improves hepatic steatosis but exacerbates liver damage and fibrosis in obese mice with nonalcoholic steatohepatitis.

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7 January 2021

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