Effects of statins on nitric oxide/cGMP signaling in human umbilical vein endothelial cells (Q43111572)

14 November 2017

Effects of statins on nitric oxide/cGMP signaling in human umbilical vein endothelial cells (English)

1 reference

14 November 2017

0 references

5

1 reference

14 November 2017

3

Olga Mykhaylyk

1 reference

14 November 2017

Claudia Meda

1

1 reference

14 November 2017

Christian Plank

series ordinal

2

1 reference

14 November 2017

Kurt Schmidt

series ordinal

4

1 reference

14 November 2017

Bernd Mayer

series ordinal

5

0 references

publication date

1 January 2010

1 reference

14 November 2017

January 2010

0 references

published in

Pharmacological Reports

1 reference

14 November 2017

62

1 reference

14 November 2017

100-112

1 reference

14 November 2017

1

1 reference

Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression

14 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Tetrahydrobiopterin, but not L-arginine, decreases NO synthase uncoupling in cells expressing high levels of endothelial NO synthase

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

3-Hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors, atorvastatin and simvastatin, induce apoptosis of vascular smooth muscle cells by downregulation of Bcl-2 expression and Rho A prenylation

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Endothelial dysfunction: a key to the pathophysiology and natural history of peripheral arterial disease?

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Endothelial dysfunction: from molecular mechanisms to measurement, clinical implications, and therapeutic opportunities

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Hsp90 and caveolin are key targets for the proangiogenic nitric oxide-mediated effects of statins.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

The intimate relation between nitric oxide and superoxide in apoptosis and cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Effects of statins on endothelium and signaling mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Beta4 integrin is involved in statin-induced endothelial cell death

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Hydroxy-methylglutaryl-coenzyme A reductase inhibition promotes endothelial nitric oxide synthase activation through a decrease in caveolin abundance

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Hypercholesterolemia decreases nitric oxide production by promoting the interaction of caveolin and endothelial nitric oxide synthase

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Caveolin mRNA levels are up-regulated by free cholesterol and down-regulated by oxysterols in fibroblast monolayers

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Janus-faced role of endothelial NO synthase in vascular disease: uncoupling of oxygen reduction from NO synthesis and its pharmacological reversal

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Withdrawal of cerivastatin from the world market

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Regulation of the mevalonate pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Interaction of endothelial and neuronal nitric-oxide synthases with the bradykinin B2 receptor. Binding of an inhibitory peptide to the oxygenase domain blocks uncoupled NADPH oxidation

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Caveolae and caveolins in the cardiovascular system

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

HMG-CoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetrahydrobiopterin in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

All hydrophobic HMG-CoA reductase inhibitors induce apoptotic death in rat pulmonary vein endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Supplementation with tetrahydrobiopterin prevents the cardiovascular effects of angiotensin II-induced oxidative and nitrosative stress

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Nitric oxide as a bifunctional regulator of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Determination of nitric oxide synthase cofactors: heme, FAD, FMN, and tetrahydrobiopterin

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Endothelial dysfunction, oxidative stress and inflammation in atherosclerosis: beneficial effects of statins.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Neuroprotection mediated by changes in the endothelial actin cytoskeleton.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Direct vascular effects of HMG-CoA reductase inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Characterization of Recombinant Human Endothelial Nitric-oxide Synthase Purified from the YeastPichia pastoris

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Nitric oxide in the pathogenesis of vascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Inhibition of protein geranylgeranylation and RhoA/RhoA kinase pathway induces apoptosis in human endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Posttranslational modification of proteins by isoprenoids in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Current perspectives on statins

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Molecular mechanisms of inhibition of porcine brain nitric oxide synthase by the antinociceptive drug 7-nitro-indazole

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Pathophysiology, diagnosis and prognostic implications of endothelial dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Magnetic nanoparticle formulations for DNA and siRNA delivery

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Caveolae as organizers of pharmacologically relevant signal transduction molecules

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Rosuvastatin decreases caveolin-1 and improves nitric oxide-dependent heart rate and blood pressure variability in apolipoprotein E-/- mice in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

The magnetofection method: using magnetic force to enhance gene delivery.

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Differential modulation of caveolin-1 expression in cells of the vasculature by statins

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Caveolin-1, a putative tumour suppressor gene

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Rho GTPases, statins, and nitric oxide

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Evaluation of ubiquinone concentration and mitochondrial function relative to cerivastatin-induced skeletal myopathy in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Endothelial dysfunction, impaired endogenous platelet inhibition and platelet activation in diabetes and atherosclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Lovastatin-stimulated superinduction of E-selectin, ICAM-1 and VCAM-1 in TNF-alpha activated human vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Effect of calcium on endothelium-derived relaxing factor formation and cGMP levels in endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Tetrahydrobiopterin-dependent formation of endothelium-derived relaxing factor (nitric oxide) in aortic endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Pitavastatin restores vascular dysfunction in insulin-resistant state by inhibiting NAD(P)H oxidase activity and uncoupled endothelial nitric oxide synthase-dependent superoxide production

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Novel approaches to improving endothelium-dependent nitric oxide-mediated vasodilatation

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Double-edged role of statins in angiogenesis signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Reaction of tetrahydrobiopterin with superoxide: EPR-kinetic analysis and characterization of the pteridine radical

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Cerivastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase, inhibits endothelial cell proliferation induced by angiogenic factors in vitro and angiogenesis in in vivo models

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Improvement of nitric oxide-dependent vasodilatation by HMG-CoA reductase inhibitors through attenuation of endothelial superoxide anion formation

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Effects of different statins on endothelial nitric oxide synthase and AKT phosphorylation in endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Statins have biphasic effects on angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

Defects in caveolin-1 cause dilated cardiomyopathy and pulmonary hypertension in knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS1734-1140%2810%2970247-4

7 January 2021

10.1016/S1734-1140(10)70247-4

Identifiers

DOI

0 references

1 reference