Pharmacodynamics of the antibacterial effect and emergence of resistance to tomopenem, formerly RO4908463/CS-023, in an in vitro pharmacokinetic model of Staphylococcus aureus infection (Q43111815)

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scientific article published on 28 January 2008

Language	Label	Description	Also known as
English	Pharmacodynamics of the antibacterial effect and emergence of resistance to tomopenem, formerly RO4908463/CS-023, in an in vitro pharmacokinetic model of Staphylococcus aureus infection	scientific article published on 28 January 2008

Statements

scholarly article

1 reference

Europe PubMed Central

14 November 2017

Pharmacodynamics of the antibacterial effect and emergence of resistance to tomopenem, formerly RO4908463/CS-023, in an in vitro pharmacokinetic model of Staphylococcus aureus infection (English)

1 reference

Europe PubMed Central

14 November 2017

Staphylococcus aureus

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

pharmacodynamics

1 reference

based on heuristic

inferred from title

author name string

Alasdair P MacGowan

1

1 reference

Europe PubMed Central

14 November 2017

Karen E Bowker

2

1 reference

Europe PubMed Central

14 November 2017

Alan R Noel

3

1 reference

Europe PubMed Central

14 November 2017

language of work or name

0 references

publication date

28 January 2008

1 reference

Europe PubMed Central

14 November 2017

Antimicrobial Agents and Chemotherapy

1 reference

Europe PubMed Central

14 November 2017

52

1 reference

Europe PubMed Central

14 November 2017

4

1 reference

Europe PubMed Central

14 November 2017

1401-1406

1 reference

Europe PubMed Central

14 November 2017

Pharmacokinetics and disposition of CS-023 (RO4908463), a novel parenteral carbapenem, in animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

25 May 2018

Pharmacokinetics of CS-023 (RO4908463), a novel parenteral carbapenem, in healthy male Caucasian volunteers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

25 May 2018

Pharmacodynamics of a new cephalosporin, PPI-0903 (TAK-599), active against methicillin-resistant Staphylococcus aureus in murine thigh and lung infection models: identification of an in vivo pharmacokinetic-pharmacodynamic target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

25 May 2018

In vitro and in vivo antibacterial activities of CS-023 (RO4908463), a novel parenteral carbapenem

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

25 May 2018

Synthesis and structure-activity relationships of novel parenteral carbapenems, CS-023 (R-115685) and related compounds containing an amidine moiety

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

25 May 2018

Activities of moxifloxacin against, and emergence of resistance in, Streptococcus pneumoniae and Pseudomonas aeruginosa in an in vitro pharmacokinetic model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

25 May 2018

Pharmacokinetic and pharmacodynamic models of the antistaphylococcal effects of meropenem and cloxacillin in vitro and in experimental infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

25 May 2018

The postantibiotic effect of imipenem: relationship with drug concentration, duration of exposure, and MIC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

25 May 2018

Relationships between antimicrobial effect and area under the concentration-time curve as a basis for comparison of modes of antibiotic administration: meropenem bolus injections versus continuous infusions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

25 May 2018

In vitro postantibiotic effect following repeated exposure to imipenem, temafloxacin, and tobramycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

25 May 2018

Comparative antibiotic dose-effect relations at several dosing intervals in murine pneumonitis and thigh-infection models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

25 May 2018

Vancomycin for Staphylococcus aureus endocarditis in intravenous drug users

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

25 May 2018

Integration of pharmacokinetics and pharmacodynamics of imipenem in a human-adapted mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

25 May 2018

Slow response to vancomycin or vancomycin plus rifampin in methicillin-resistant Staphylococcus aureus endocarditis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

25 May 2018

Bactericidal activity of meropenem and interactions with other antibiotics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

25 May 2018

Comparative activity of cloxacillin and vancomycin against methicillin-susceptible Staphylococcus aureus experimental endocarditis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

15 August 2018

CS-023 (R-115685), a novel carbapenem with enhanced in vitro activity against oxacillin-resistant staphylococci and Pseudomonas aeruginosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

15 August 2018

In vivo and in vitro study of several pharmacodynamic effects of meropenem

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

15 August 2018

Bactericidal activity of two different dosage regimens of imipenem in an in-vitro dynamic model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2292562

15 August 2018

Comparative pharmacodynamics of meropenem using an in-vitro model to simulate once, twice and three times daily dosing in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/18227179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bactericidal activity, post antibiotic effect and modified controlled effective regrowth time of meropenem at high concentrations

1 reference

https://pubmed.ncbi.nlm.nih.gov/18227179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamic effects of amikacin, ciprofloxacin and imipenem on growing and non-growing Escherichia coli and Pseudomonas aeruginosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/18227179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Classification of betalactam antibiotics according to their pharmacodynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/18227179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FCE 22101 and FCE 22891: in-vitro antibacterial activity at concentrations simulating human plasma levels following intravenous, intramuscular and oral administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/18227179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.01153-07

1 reference

Europe PubMed Central

14 November 2017

1 reference

Europe PubMed Central

14 November 2017

1 reference

Europe PubMed Central

14 November 2017

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0 references

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