Characterization of a novel intraocular drug-delivery system using crystalline lipid antiviral prodrugs of ganciclovir and cyclic cidofovir. (Q43149101)

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4 January 2020

title

Characterization of a novel intraocular drug-delivery system using crystalline lipid antiviral prodrugs of ganciclovir and cyclic cidofovir (English)

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4 January 2020

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2

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4 January 2020

author name string

Lingyun Cheng

1

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4 January 2020

Jeffery Lee

3

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4 January 2020

Hyoung Jun Koh

4

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4 January 2020

James R Beadle

5

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4 January 2020

Kenichiro Bessho

6

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4 January 2020

Mitsuko Toyoguchi

7

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4 January 2020

Kathy Aldern

8

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Jean-Marc Bovet

9

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4 January 2020

William R Freeman

10

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4 January 2020

language of work or name

English

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publication date

1 November 2004

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Investigative Ophthalmology Visual Science

4 January 2020

published in

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volume

45

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issue

11

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4 January 2020

page(s)

4138-4144

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Alkoxyalkyl esters of cidofovir and cyclic cidofovir exhibit multiple-log enhancement of antiviral activity against cytomegalovirus and herpesvirus replication in vitro

4 January 2020

cites work

1 reference

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Synthesis and anti-rhinovirus activity of 2-styrylchromones

25 May 2018

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Treatment of herpes retinitis in an animal model with a sustained delivery antiviral drug, liposomal 1-O-octadecyl-SN-glycerol-3-phosphonoformate

25 May 2018

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Intravitreal toxicology in rabbits of two preparations of 1-O-octadecyl-sn-glycerol-3-phosphonoformate, a sustained-delivery anti-CMV drug

25 May 2018

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1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl] cytosine, an intracellular prodrug for (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine with improved therapeutic index in vivo

25 May 2018

1 reference

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Factors affecting the intraocular penetration of antibiotics. The influence of route, inflammation, animal species and tissue pigmentation

25 May 2018

1 reference

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Ganciclovir release rates in vitreous from different formulations of 1-O-hexadecylpropanediol-3-phospho-ganciclovir

25 May 2018

1 reference

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Increased antiviral activity of 1-O-hexadecyloxypropyl-[2-(14)C]cidofovir in MRC-5 human lung fibroblasts is explained by unique cellular uptake and metabolism.

15 August 2018

1 reference

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Hypotony after intravenous cidofovir therapy for the treatment of cytomegalovirus retinitis

15 August 2018

1 reference

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Treatment or prevention of herpes simplex virus retinitis with intravitreally injectable crystalline 1-O-hexadecylpropanediol-3-phospho-ganciclovir.

15 August 2018

1 reference

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Intraocular pressure and aqueous humor dynamics in patients with AIDS treated with intravitreal cidofovir (HPMPC) for cytomegalovirus retinitis

15 August 2018

1 reference

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The role of gravity in gentamicin-induced toxic effects in a rabbit model.

15 August 2018

1 reference

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Distribution and metabolism of intravitreal cidofovir and cyclic HPMPC in rabbits

15 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15505067

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1167/IOVS.04-0064

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4 January 2020

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4 January 2020

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