High affinity interaction of mibefradil with voltage-gated calcium and sodium channels. (Q43167290)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10821797%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

title

High affinity interaction of mibefradil with voltage-gated calcium and sodium channels (English)

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6 November 2019

0 references

9

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6 November 2019

author name string

P Eller

1

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6 November 2019

S Berjukov

2

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6 November 2019

S Wanner

3

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6 November 2019

I Huber

4

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6 November 2019

S Hering

5

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6 November 2019

H G Knaus

6

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6 November 2019

G Toth

7

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6 November 2019

S D Kimball

8

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6 November 2019

language of work or name

English

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publication date

1 June 2000

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British Journal of Pharmacology

6 November 2019

published in

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6 November 2019

volume

130

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6 November 2019

issue

3

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6 November 2019

page(s)

669-677

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Protein measurement with the Folin phenol reagent

6 November 2019

cites work

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25 May 2018

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25 May 2018

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Mibefradil (Ro 40-5967) inhibits several Ca2+ and K+ currents in human fusion-competent myoblasts.

25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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Alternatively spliced IS6 segments of the alpha 1C gene determine the tissue-specific dihydropyridine sensitivity of cardiac and vascular smooth muscle L-type Ca2+ channels

25 May 2018

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Blockade of N-type Ca2+ current by cilnidipine (FRC-8653) in acutely dissociated rat sympathetic neurones.

25 May 2018

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Block of P/Q-type calcium channels by therapeutic concentrations of aminoglycoside antibiotics.

25 May 2018

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Riluzole. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in amyotrophic lateral sclerosis

25 May 2018

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Antiepileptic drug mechanisms of action

25 May 2018

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Ligand-induced accelerated dissociation of (+)-cis-diltiazem from L-type Ca2+ channels is simply explained by competition for individual attachment points

25 May 2018

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Extracellular localization of the benzothiazepine binding domain of L-type Ca2+ channels

25 May 2018

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Coordination of Ca2+ by the pore region glutamates is essential for high-affinity dihydropyridine binding to the cardiac Ca2+ channel alpha 1 subunit.

25 May 2018

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Actions of the novel neuroprotective agent, lifarizine (RS-87476), on voltage-dependent sodium currents in the neuroblastoma cell line, N1E-115.

25 May 2018

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25 May 2018

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Voltage-dependent blockade of diverse types of voltage-gated Ca2+ channels expressed in Xenopus oocytes by the Ca2+ channel antagonist mibefradil (Ro 40-5967)

25 May 2018

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Temperature‐dependent regulation of d‐cis‐[3H]diltiazem binding to Ca2+ channels by 1,4‐dihydropyridine channel agonists and antagonists

25 May 2018

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25 May 2018

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(-)-[3H]Desmethoxyverapamil, a novel Ca2+ channel probe. Binding characteristics and target size analysis of its receptor in skeletal muscle

25 May 2018

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25 May 2018

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Photoaffinity-labelling of the calcium-channel-associated 1,4-dihydropyridine and phenylalkylamine receptor in guinea-pig hippocampus. A 195 kDa polypeptide carries both drug receptors and has similarities to the alpha 1 subunit of the purified skel

25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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25 May 2018

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15 August 2018

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15 August 2018

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15 August 2018

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15 August 2018

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Target size analysis and molecular properties of Ca2+ channels labelled with [3H]verapamil.

15 August 2018

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15 August 2018

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15 August 2018

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12 December 2020

In vitro pharmacologic profile of Ro 40-5967, a novel Ca2+ channel blocker with potent vasodilator but weak inotropic action

1 reference

12 December 2020

Selective inhibition of T-type Ca2+ channels by Ro 40-5967

1 reference

12 December 2020

The naming of voltage-gated calcium channels

1 reference

12 December 2020

The Ca(++)-channel blocker Ro 40-5967 blocks differently T-type and L-type Ca++ channels

1 reference

12 December 2020

The binding interactions of Ro 40-5967 at the L-type Ca2+ channel in cardiac tissue

1 reference

12 December 2020

Comparison of binding of 3H-desmethoxyverapamil and 3H-mibefradil in vascular smooth muscle and heart membranes. Possible binding of mibefradil to a site distinct from the phenylalkylamine-binding site

1 reference

12 December 2020

Molecular determinants of high affinity phenylalkylamine block of L-type calcium channels in transmembrane segment IIIS6 and the pore region of the alpha1 subunit.

1 reference

12 December 2020

Structural basis of drug binding to L Ca2+ channels

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12 December 2020

Identifiers

DOI

10.1038/SJ.BJP.0703352

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10821797%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10821797%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10821797%20AND%20SRC:MED&resulttype=core&format=json