ET(A) receptors are the primary mediators of myofilament calcium sensitization induced by ET-1 in rat pulmonary artery smooth muscle: a tyrosine kinase independent pathway. (Q43192104)

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scientific article published in May 1999

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English	ET(A) receptors are the primary mediators of myofilament calcium sensitization induced by ET-1 in rat pulmonary artery smooth muscle: a tyrosine kinase independent pathway.	scientific article published in May 1999

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8 December 2019

ET(A) receptors are the primary mediators of myofilament calcium sensitization induced by ET-1 in rat pulmonary artery smooth muscle: a tyrosine kinase independent pathway (English)

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8 December 2019

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8 December 2019

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A M Evans

1

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8 December 2019

H J Cobban

2

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8 December 2019

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1 May 1999

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8 December 2019

British Journal of Pharmacology

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8 December 2019

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8 December 2019

1

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8 December 2019

153-160

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8 December 2019

Endothelin receptors mediating contraction of rat and human pulmonary resistance arteries: effect of chronic hypoxia in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Regulation of the resting potential of rabbit pulmonary artery myocytes by a low threshold, O2-sensing potassium current

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Involvement of tyrosine phosphorylation in endothelin-1-induced calcium-sensitization in rat small mesenteric arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

EndothelinB receptor-mediated contraction in human pulmonary resistance arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Failure of BQ123, a more potent antagonist of sarafotoxin 6b than of endothelin-1, to distinguish between these agonists in binding experiments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Phosphorylation of caldesmon by mitogen-activated protein kinase with no effect on Ca2+ sensitivity in rabbit smooth muscle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

The role of the endothelium in hypoxic pulmonary vasoconstriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Endothelin-1 does not mediate hypoxic vasoconstriction in canine isolated blood vessels: effect of BQ-123.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Hypoxia reduces potassium currents in cultured rat pulmonary but not mesenteric arterial myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Hypoxic vasoconstriction in rat pulmonary and mesenteric arteries.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Vasoconstrictor and vasodilator effects of hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Introduction of high molecular weight (IgG) proteins into receptor coupled, permeabilized smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Long‐lasting activation of cation current by low concentration of endothelin‐1 in mouse fibroblasts and smooth muscle cells of rabbit aorta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Myosin light chain phosphorylation associated with contraction in arterial smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Endothelin activates the dihydropyridine-sensitive, voltage-dependent Ca2+ channel in vascular smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Receptor-coupled, permeabilized smooth muscle. Role of the phosphatidylinositol cascade, G-proteins, and modulation of the contractile response to Ca2+.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Cloning of a cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Cloning and expression of a cDNA encoding an endothelin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Biphasic contractile response of pulmonary artery to hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Cloning and functional expression of human cDNA for the ETB endothelin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

G-protein-mediated Ca2+ sensitization of smooth muscle contraction through myosin light chain phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Endothelin and calcium dynamics in vascular smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Normobaric hypoxia stimulates endothelin-1 gene expression in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Effects of hypoxia and other vasoactive agents on pulmonary and cerebral artery smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Pulmonary arterial hypoxic contraction: signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Endothelin increases myofilament Ca2+ sensitivity in alpha-toxin-permeabilized rabbit mesenteric artery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

BQ123, an ETA-receptor antagonist, attenuates hypoxic pulmonary hypertension in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

25 May 2018

Expression of endothelin-1 in the lungs of patients with pulmonary hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

15 August 2018

Acute hypoxia increases cytosolic calcium in fetal pulmonary artery smooth muscle cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1566012

15 August 2018

Mechanisms of vasoconstriction induced by endothelin-1 in smooth muscle of rabbit mesenteric artery

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelium-derived contracting and relaxing factors contribute to hypoxic responses of pulmonary arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelin-1 stimulates phosphatidylinositol hydrolysis and calcium uptake in isolated canine coronary arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoforms of the phosphorylatable myosin light chain in arterial smooth muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Some properties of the contractile system and sarcoplasmic reticulum of skinned slow fibres from Xenopus muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelin receptor subtypes in human versus rabbit pulmonary arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelin-1 induces vasoconstriction through two functionally distinct pathways in porcine coronary artery: contribution of phosphoinositide turnover

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ET(A) receptor blockade prevents increased tissue endothelin-1, vascular hypertrophy, and endothelial dysfunction in salt-sensitive hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The orally active ET(A) receptor antagonist (+)-(S)-2-(4,6-dimethoxy-pyrimidin-2-yloxy)-3-methoxy-3,3-diphe nyl-propionic acid (LU 135252) prevents the development of pulmonary hypertension and endothelial metabolic dysfunction in monocrotaline-trea

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desensitization to cytoplasmic Ca2+ and Ca2+ sensitivities of guinea-pig ileum and rabbit pulmonary artery smooth muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxic vasoconstriction and intracellular Ca2+ in pulmonary arteries: evidence for PKC-independent Ca2+ sensitization

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma endothelin concentrations in patients with pulmonary hypertension associated with congenital heart defects. Evidence for increased production of endothelin in pulmonary circulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Properties of a novel K+ current that is active at resting potential in rabbit pulmonary artery smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased endothelin receptor gene expression in hypoxic rat lung

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced endothelin-1 and endothelin receptor gene expression in chronic hypoxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of hypoxic pulmonary vasoconstriction by calcium antagonists in isolated rat lungs

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxic induction of Ca2+-dependent action potentials in small pulmonary arteries of the cat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute hypoxia increases cytosolic calcium in cultured pulmonary arterial myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The orally active nonpeptide endothelin A-receptor antagonist A-127722 prevents and reverses hypoxia-induced pulmonary hypertension and pulmonary vascular remodeling in Sprague-Dawley rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of hypoxia and norepinephrine on cytoplasmic free Ca2+ in pulmonary and cerebral arterial myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of hypoxia on endothelin-1 binding sites in neonatal porcine pulmonary vasculature

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relaxation of endothelin-1-induced pulmonary arterial constriction by niflumic acid and NPPB: mechanism(s) independent of chloride channel block

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelin-1 in acute lung injury and the adult respiratory distress syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxic pulmonary endothelial cells release a diffusible contractile factor distinct from endothelin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterisation of the endothelin receptor mediating contraction of human pulmonary artery using BQ123 and Ro 46-2005

1 reference

https://pubmed.ncbi.nlm.nih.gov/10369468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1038/SJ.BJP.0702548

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10369468%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10369468%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10369468%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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