An evaluation of the genotoxic and cytotoxic effects of the anti-obesity drugs sibutramine and fenproporex (Q43201843)

16 November 2017

An evaluation of the genotoxic and cytotoxic effects of the anti-obesity drugs sibutramine and fenproporex (English)

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16 November 2017

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Catarina Satie Takahashi

object named as

Catarina Satie Takahashi

series ordinal

3

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author name string

Cristiano José da Silva

series ordinal

1

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PubMed ID

20051455

16 November 2017

José Ernesto dos Santos

series ordinal

2

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PubMed ID

20051455

16 November 2017

language of work or name

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5 January 2010

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Human & Experimental Toxicology

16 November 2017

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16 November 2017

29

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16 November 2017

3

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16 November 2017

187-197

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Pharmacotherapy for obesity.

16 November 2017

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

A review of the genotoxicity of marketed pharmaceuticals

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

In vivo micronucleus test in mice with 1-phenylethanol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

In vivo rodent micronucleus assay: protocol, conduct and data interpretation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

The in vitro micronucleus technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

The discovery and status of sibutramine as an anti-obesity drug

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Obesity and colorectal cancer: epidemiology, mechanisms and candidate genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Evaluation of the genotoxic potential of the natural neurotoxin Tetrodotoxin (TTX) in a battery of in vitro and in vivo genotoxicity assays.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Application of the micronucleus test to exfoliated cells of high cancer risk groups: tobacco chewers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Micronucleated cells in nasal mucosa of formaldehyde-exposed workers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

The contribution of cytotoxicity to DNA-effects in the single cell gel test (comet assay).

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

The kinetics of repair of oxidative DNA damage (strand breaks and oxidised pyrimidines) in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

The comet assay: topical issues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Measurement of micronucleated erythrocytes and DNA damage during chronic ingestion of phenolphthalein in transgenic female mice heterozygous for the p53 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

21 January 2018

Sibutramine in pregnancy

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Early first-trimester sibutramine exposure : pregnancy outcome and neonatal follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Effects of sibutramine and orlistat on mood in obese and overweight subjects: a randomised study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Serotonin and norepinephrine reuptake inhibition and eating behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Diabesity: are weight loss medications effective?

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Behavioral neurotoxicity in adolescent and adult mice exposed to fenproporex during pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Fenproporex N-dealkylation to amphetamine--enantioselective in vitro studies in human liver microsomes as well as enantioselective in vivo studies in Wistar and Dark Agouti rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Alternative mitochondrial functions in cell physiopathology: beyond ATP production

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Mitochondrial superoxide: production, biological effects, and activation of uncoupling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Internal hazards: baseline DNA damage by endogenous products of normal metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Towards a molecular understanding of adaptive thermogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

A selective human beta3 adrenergic receptor agonist increases metabolic rate in rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Mitochondrial uncoupling: role of uncoupling protein anion carriers and relationship to thermogenesis and weight control "the benefits of losing control".

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Role of UCP2 and UCP3 in nutrition and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Sample size for the estimation of polychromatic to normochromatic erythrocyte ratio in the bone marrow micronucleus test.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

The in vivo micronucleus assay in mammalian bone marrow and peripheral blood. A report of the U.S. Environmental Protection Agency Gene-Tox Program

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Methylphenidate is not clastogenic in cultured human lymphocytes and in the mouse bone-marrow micronucleus test

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

The use of the comet assay in the study of human nutrition and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Potential use of the comet assay in the clinical management of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

The comet assay in human biomonitoring: gene-environment interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Use of the alkaline comet assay for industrial genotoxicity screening: comparative investigation with the micronucleus test.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Dose translation from animal to human studies revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

Obesity in the new millennium

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F0960327109358732

21 January 2018

Identifiers

DOI

10.1177/0960327109358732

1 reference

16 November 2017

1 reference

PubMed ID

20051455