Systemic and local anti-C5 therapy reduces the disease severity in experimental autoimmune uveoretinitis. (Q43225419)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20002447%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

title

Systemic and local anti-C5 therapy reduces the disease severity in experimental autoimmune uveoretinitis (English)

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15 January 2020

6

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15 January 2020

Bryan Paul Morgan

5

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15 January 2020

author name string

D A Copland

1

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15 January 2020

K Hussain

2

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15 January 2020

S Baalasubramanian

3

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15 January 2020

T R Hughes

4

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15 January 2020

A D Dick

7

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15 January 2020

L B Nicholson

8

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15 January 2020

publication date

4 December 2009

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Clinical and Experimental Immunology

15 January 2020

published in

1 reference

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15 January 2020

volume

159

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15 January 2020

issue

3

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15 January 2020

page(s)

303-314

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Suppression of complement regulatory proteins (CRPs) exacerbates experimental autoimmune anterior uveitis (EAAU).

15 January 2020

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Immunomodulation of experimental autoimmune uveoretinitis: a model of tolerance induction with retinal antigens

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IFN-gamma and IL-17 production in experimental autoimmune encephalomyelitis depends on local APC-T cell complement production

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Complement component 5a (C5a)

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Analysis of retinal cellular infiltrate in experimental autoimmune uveoretinitis reveals multiple regulatory cell populations

29 September 2018

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The clinical time-course of experimental autoimmune uveoretinitis using topical endoscopic fundal imaging with histologic and cellular infiltrate correlation

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29 September 2018

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Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cells

29 September 2018

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29 September 2018

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29 September 2018

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Monoclonal antibody-mediated CD200 receptor signaling suppresses macrophage activation and tissue damage in experimental autoimmune uveoretinitis

29 September 2018

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29 September 2018

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The complement system plays a critical role in the development of experimental autoimmune anterior uveitis

29 September 2018

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Drusen complement components C3a and C5a promote choroidal neovascularization

29 September 2018

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Genetic deficiency of C3 as well as CNS-targeted expression of the complement inhibitor sCrry ameliorates experimental autoimmune uveoretinitis

29 September 2018

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Immunological factors in the pathogenesis and treatment of age-related macular degeneration

29 September 2018

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29 September 2018

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29 September 2018

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The role of tumour necrosis factor (TNF-alpha) in experimental autoimmune uveoretinitis (EAU).

29 September 2018

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29 September 2018

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29 September 2018

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Regulation, counter-regulation, and immunotherapy of autoimmune responses to immunologically privileged retinal antigens

29 September 2018

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29 September 2018

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29 September 2018

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29 September 2018

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29 September 2018

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29 September 2018

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29 September 2018

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29 September 2018

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29 September 2018

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Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease

29 September 2018

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29 September 2018

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Macrophage-derived nitric oxide inhibits the proliferation of activated T helper cells and is induced during antigenic stimulation of resting T cells

29 September 2018

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29 September 2018

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Neutralizing TNF-alpha activity modulates T-cell phenotype and function in experimental autoimmune uveoretinitis

29 September 2018

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Experimental approaches to specific immunotherapies in autoimmune disease: future treatment of endogenous posterior uveitis?

29 September 2018

1 reference

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Anti-C5 monoclonal antibody therapy prevents collagen-induced arthritis and ameliorates established disease

29 September 2018

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29 September 2018

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29 September 2018

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29 September 2018

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29 September 2018

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Inhibition of autoimmune uveitis by anti-CD4 antibody

29 September 2018

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The chemotactic receptor for human C5a anaphylatoxin

29 September 2018

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Proctor Lecture. Experimental allergic uveitis. Investigations of retinal autoimmunity and the immunopathologic responses evoked

29 September 2018

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Immunogenetic aspects of clinical and experimental uveitis

29 September 2018

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Oral tolerance in a murine model of relapsing experimental autoimmune uveoretinitis (EAU): induction of protective tolerance in primed animals

29 September 2018

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Recombinant C5a enhances interleukin 1 and tumor necrosis factor release by lipopolysaccharide-stimulated monocytes and macrophages

3 November 2018

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12 December 2020

Nitric oxide accelerates the onset and increases the severity of experimental autoimmune uveoretinitis through an IFN-gamma-dependent mechanism

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12 December 2020

Marrow-derived activated macrophages are required during the effector phase of experimental autoimmune uveoretinitis in rats

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12 December 2020

Blockade of the C5a receptor fails to protect against experimental autoimmune encephalomyelitis in rats

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12 December 2020

Dendritic cell synthesis of C3 is required for full T cell activation and development of a Th1 phenotype

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12 December 2020

TNFR1-dependent regulation of myeloid cell function in experimental autoimmune uveoretinitis

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12 December 2020

IFN-gamma and LPS-mediated IL-10-dependent suppression of retinal microglial activation

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12 December 2020

Targeted deletion of the CD59 gene causes spontaneous intravascular hemolysis and hemoglobinuria

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12 December 2020

Production of cyclooxygenase products and superoxide anion by macrophages in response to chemotactic factors

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12 December 2020

Generation of a monoclonal antibody to mouse C5 application in an ELISA assay for detection of anti-CS antibodies

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12 December 2020

10.1111/J.1365-2249.2009.04070.X

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20002447%20AND%20SRC:MED&resulttype=core&format=json

15 January 2020

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