An intersubunit hydrogen bond in the nicotinic acetylcholine receptor that contributes to channel gating. (Q43227834)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18952603%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

An intersubunit hydrogen bond in the nicotinic acetylcholine receptor that contributes to channel gating (English)

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25 December 2019

3

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25 December 2019

author name string

Kristin Rule Gleitsman

series ordinal

1

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25 December 2019

Sean M A Kedrowski

series ordinal

2

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25 December 2019

Dennis A Dougherty

series ordinal

4

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25 December 2019

language of work or name

English

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publication date

24 October 2008

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Journal of Biological Chemistry

25 December 2019

published in

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25 December 2019

volume

283

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25 December 2019

issue

51

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25 December 2019

page(s)

35638-35643

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Chemical-scale studies on the role of a conserved aspartate in preorganizing the agonist binding site of the nicotinic acetylcholine receptor

25 December 2019

cites work

1 reference

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In vivo incorporation of multiple unnatural amino acids through nonsense and frameshift suppression.

25 May 2018

1 reference

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Ligand-induced conformational changes in the acetylcholine-binding protein analyzed by hydrogen-deuterium exchange mass spectrometry

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2602911

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2602911

Refined structure of the nicotinic acetylcholine receptor at 4A resolution

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2602911

Acetylcholine binding protein (AChBP): a secreted glial protein that provides a high-resolution model for the extracellular domain of pentameric ligand-gated ion channels.

25 May 2018

1 reference

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Coupling of agonist binding to channel gating in the GABA(A) receptor

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2602911

Naturally occurring mutations at the acetylcholine receptor binding site independently alter ACh binding and channel gating.

25 May 2018

1 reference

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Emerging structure of the nicotinic acetylcholine receptors

25 May 2018

1 reference

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Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2602911

Nicotinic receptors at the amino acid level

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2602911

Mapping the conformational wave of acetylcholine receptor channel gating

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2602911

A mutational analysis of the acetylcholine receptor channel transmitter binding site

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2602911

From ab initio quantum mechanics to molecular neurobiology: a cation-pi binding site in the nicotinic receptor

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2602911

In vivo incorporation of unnatural amino acids into ion channels in Xenopus oocyte expression system.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2602911

Negatively charged amino acid residues in the nicotinic receptor delta subunit that contribute to the binding of acetylcholine

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2602911

Channel gating governed symmetrically by conserved leucine residues in the M2 domain of nicotinic receptors

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2602911

Solvation energy in protein folding and binding

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2602911

Influence of agonists and antagonists on the segmental motion of residues near the agonist binding pocket of the acetylcholine-binding protein

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2602911

Nicotinic acetylcholine receptor at 4.6 A resolution: transverse tunnels in the channel wall.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2602911

Backbone mutations in transmembrane domains of a ligand-gated ion channel: implications for the mechanism of gating.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2602911

The role of conserved leucines in the M2 domain of the acetylcholine receptor in channel gating.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2602911

Rapid chromatographic technique for preparative separations with moderate resolution

15 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M807226200

Safe and Convenient Procedure for Solvent Purification

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M807226200

Functional effects on the acetylcholine receptor of multiple mutations of gamma Asp174 and delta Asp180

21 January 2018

1 reference

12 December 2020

Transducing agonist binding to channel gating involves different interactions in 5-HT3 and GABAC receptors

1 reference

12 December 2020

Nicotinic receptors in wonderland

1 reference

12 December 2020

Agonist binding site of Torpedo electric tissue nicotinic acetylcholine receptor. A negatively charged region of the delta subunit within 0.9 nm of the alpha subunit binding site disulfide

1 reference

12 December 2020

Structure of the nicotinic receptor acetylcholine-binding site. Identification of acidic residues in the delta subunit within 0.9 nm of the 5 alpha subunit-binding

1 reference

12 December 2020

The contributions of aspartyl residues in the acetylcholine receptor gamma and delta subunits to the binding of agonists and competitive antagonists

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M807226200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18952603%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18952603%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

PubMed publication ID

18952603

1 reference