Insulin-stimulated phosphorylation of endothelial nitric oxide synthase at serine-615 contributes to nitric oxide synthesis. (Q43238697)

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12 February 2020

title

Insulin-stimulated phosphorylation of endothelial nitric oxide synthase at serine-615 contributes to nitric oxide synthesis (English)

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12 February 2020

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7

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12 February 2020

author name string

Stuart A Ritchie

1

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12 February 2020

Christine F Kohlhaas

2

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12 February 2020

Alasdair R Boyd

3

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12 February 2020

Krishna C Yalla

4

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12 February 2020

Kenneth Walsh

5

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12 February 2020

John M C Connell

6

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language of work or name

English

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publication date

27 January 2010

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12 February 2020

number of pages

6

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based on heuristic

inferred from page(s)

published in

Biochemical Journal

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volume

426

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issue

1

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page(s)

85-90

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Endothelial dysfunction in diabetes: from mechanisms to therapeutic targets.

12 February 2020

cites work

1 reference

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Vascular actions of insulin with implications for endothelial dysfunction

21 January 2018

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Insulin-mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release

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The vasodilating effect of insulin is dependent on local glucose uptake: a double blind, placebo-controlled study

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Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells

21 January 2018

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High glucose inhibits insulin-stimulated nitric oxide production without reducing endothelial nitric-oxide synthase Ser1177 phosphorylation in human aortic endothelial cells.

21 January 2018

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Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation

21 January 2018

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Compensatory phosphorylation and protein-protein interactions revealed by loss of function and gain of function mutants of multiple serine phosphorylation sites in endothelial nitric-oxide synthase

21 January 2018

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Identification of regulatory sites of phosphorylation of the bovine endothelial nitric-oxide synthase at serine 617 and serine 635.

21 January 2018

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Acute activation and phosphorylation of endothelial nitric oxide synthase by HMG-CoA reductase inhibitors

21 January 2018

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Rosiglitazone stimulates nitric oxide synthesis in human aortic endothelial cells via AMP-activated protein kinase.

21 January 2018

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AMP-activated protein kinase mediates VEGF-stimulated endothelial NO production

21 January 2018

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Acute modulation of endothelial Akt/PKB activity alters nitric oxide-dependent vasomotor activity in vivo

21 January 2018

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Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells

21 January 2018

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Endostatin induces acute endothelial nitric oxide and prostacyclin release

21 January 2018

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Effects of combined phosphorylation at Ser-617 and Ser-1179 in endothelial nitric-oxide synthase on EC50(Ca2+) values for calmodulin binding and enzyme activation

21 January 2018

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Role of eNOS phosphorylation at Ser-116 in regulation of eNOS activity in endothelial cells.

21 January 2018

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Differences in eNOS activity because of subcellular localization are dictated by phosphorylation state rather than the local calcium environment.

21 January 2018

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G972R IRS-1 variant impairs insulin regulation of endothelial nitric oxide synthase in cultured human endothelial cells

21 January 2018

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Interleukin-6 impairs the insulin signaling pathway, promoting production of nitric oxide in human umbilical vein endothelial cells

21 January 2018

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Dephosphorylation of endothelial nitric-oxide synthase by vascular endothelial growth factor. Implications for the vascular responses to cyclosporin A.

21 January 2018

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Synergistic activation of endothelial nitric-oxide synthase (eNOS) by HSP90 and Akt: calcium-independent eNOS activation involves formation of an HSP90-Akt-CaM-bound eNOS complex

21 January 2018

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Insulin and IGF-I phosphorylate eNOS in HUVECs by a caveolin-1 dependent mechanism

21 January 2018

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21 January 2018

Identifiers

DOI

10.1042/BJ20091580

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19925457%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

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